ANAC078 negatively regulates auxin synthesis by directly binding to the promoters of <i>YUC2</i>, <i>YUC4</i> and <i>GH3</i>.<i>5</i>. by Yong Tang (161879)

“…<p>A. qPCR analysis confirmed the expression of <i>ANAC078(-C)</i> in WT [<i>ANAC078(-C)ox</i>] (left), which results in the decreased IAA amount (right). …”

DataSheet_2_LncRNA xist regulates sepsis associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis.pdf by Huifang Wang (390338)

“…Furthermore, it was found that the expression of IL-1β and TNF-α were negatively correlated with the level of miR-122-5p. A high-throughput sequencing analysis showed that miR-122-5p expression was downregulated with 1.5-fold changes in the PWM of CLP rats compared with sham group. …”

DataSheet_1_LncRNA xist regulates sepsis associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis.zip by Huifang Wang (390338)

“…Furthermore, it was found that the expression of IL-1β and TNF-α were negatively correlated with the level of miR-122-5p. A high-throughput sequencing analysis showed that miR-122-5p expression was downregulated with 1.5-fold changes in the PWM of CLP rats compared with sham group. …”

DataSheet_1_Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients.doc by Isabel Castro (484905)

“…Levels of TNF-α mRNA, a direct target of hsa-miR-181d-5p, were significantly increased and negatively correlated with hsa-miR-181d-5p presence. …”

Translational Control through eIF2alpha Phosphorylation during the <em>Leishmania</em> Differentiation Process by Serge Cloutier (160605)

“…We find that exposure of promastigotes to a combined elevated temperature and acidic pH stress, a key signal triggering amastigote differentiation, leads to a marked decrease in global translation initiation, which is associated with eIF2α phosphorylation. …”

Imido Transfer from Bis(imido)ruthenium(VI) Porphyrins to Hydrocarbons:  Effect of Imido Substituents, C−H Bond Dissociation Energies, and Ru^VI/V Reduction Potentials... by Sarana Ka-Yan Leung (2661700)

“…The second-order rate constants (<i>k</i>₂) of the aziridination/amidation reactions at 298 K were determined to be (2.6 ± 0.1) × 10^-5 to 14.4 ± 0.6 dm³ mol^-1 s^-1, which generally increase with increasing Ru^VI/V reduction potential of the imido complexes and decreasing C−H bond dissociation energy (BDE) of the hydrocarbons. …”

Presentation_1_Astragaloside IV Protects 6-Hydroxydopamine-Induced SH-SY5Y Cell Model of Parkinson’s Disease via Activating the JAK2/STAT3 Pathway.PPTX by ZhengHu Xu (10347746)

“…AS-IV inhibited IL-1β, IL-6, and TNF-α level (all p < 0.05), reduced MDA and ROS content and increased SOD concentration, thereby reducing inflammation and oxidative stress (all p < 0.01) in 6-OHDA-treated SH-SY5Y cells. Moreover, AS-IV decreased apoptosis rate and Bax/Bcl-2 ratio induced by 6-OHDA (all p < 0.05). …”

Distribution of the Log₂ fold changes in proteins' expression in all groups. by Gwenael Pottiez (2216860)

“…<p>It is expected that proteins will be distributed around log2 of 0 ( = 1, no change between visits). We observed two additional peaks in Group 1 indicated by arrowheads; larger peak with log₂ of 1 corresponding to 2-fold increase and smaller peak with log₂ of approximately -2 corresponding to 7-fold decrease.…”

Systemic colonization of potato plants resulting from potato haulm inoculation with <i>Dickeya solani</i> or <i>Pectobacterium parmentieri</i> by P. Kastelein (9287217)

“…Nevertheless, infection of leaves could also occur at low densities of <i>D. solani</i> (10² cfu mL⁻¹). We further investigated the risks for translocation of the pathogens from infected haulms through soil into progeny tubers after haulm destruction. …”

DataSheet_1_Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.pdf by Yu Xiao (150812)

“…Significantly more EVs were found in the supernatant of SEN than of control (CON) cell cultures, and SEN EVs were enriched in miR-30b-5p, which directly target sirtuin1 (SIRT1). In vitro, we found that SEN EV treatment resulted in increased cellular levels of interleukin-1β (IL-1β) and IL-6 and decreased levels of SIRT1. …”

DataSheet_5_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.zip by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

Regional cerebral glucose metabolism after N-acetyl-L-leucine as compared to sham treatment following unilateral labyrinthectomy. by Lisa Günther (710539)

“…<p>The images depict group-wise comparisons of the regional cerebral glucose metabolism (rCGM) on days 1, 3, 7 and 15 after unilateral labyrinthectomy (UL). A) Compared to the sham treatment group, the N-acetyl-L-leucine group (24 mg i.v. per rat) showed on day 3 a significant decrease of rCGM in the ipsilesional, on day 7 in the ipsilesional>contralesional posterolateral thalamus and subthalamic region. …”

Video2_The impact of data sonification in virtual reality robot teleoperation.MP4 by Paul Bremner (2646193)

“…However, as the operational environment is hazardous, a sense of presence may not be desirable as it can lead to heightened operator stress. We conduct a study in which we compare the effects of diegetic sounds (literal and established sonifications) with abstract sounds (non-established sonifications). …”

DataSheet1_The Establishment of Quantitatively Regulating Expression Cassette with sgRNA Targeting BIRC5 to Elucidate the Synergistic Pathway of Survivin with P-Glycoprotein in Can... by Changping Deng (11894321)

“…In order to explore the specific functions of BIRC5 gene in multi-drug resistance (MDR), a CRISPR/Cas9-mediated knocking-in tetracycline (Tet)-off regulatory system cell line was established, which enabled us to regulate the expression levels of Survivin quantitatively (clone 8 named MCF-7/Survivin was selected for further studies). …”

A highly conserved RNA motif. by Claudia Steglich (53465)

“…The color code for shaded bases is as follows: red, all sequences have the same two nucleotides; ochre, two types of base pairs occur; green, three types of base pairs occur; turquoise, four types of base pairs occur. The saturation decreases with the number of sequences unable to form a base pair at this position. …”

SMRP is a biomarker of therapy response. by Elliot L. Servais (341149)

“…<p><i>A</i>, Nude athymic mice xenografted with human MPM tumors were treated with either: cisplatin (4 mg/kg IP weekly), isolated thoracic radiation (20Gy total in 5 fractions), combination chemoradiation, or no treatment. …”

Image_2_Synaptic Failure Differentially Affects Pattern Formation in Heterogenous Networks.JPEG by Maral Budak (6680351)

“…We found that the two structures have significantly different dynamical properties. …”

Image_2_Mitochondrial dynamics and metabolic regulation control T cell fate in the thymus.tif by Rima Elhage (17787302)

“…In addition, the glucose/IL-7R connection affects the TN3 to TN4 transition (also called β-selection transition), by enhancing the percentage of TN3, leading to a decrease in the total number of thymocytes. Thus, we identified additional components, essential during β-selection transition and playing a major role in thymic development.…”

Distribution of Tunel-positive cells in the hippocampus of rats submitted to anoxia and treated with 2-APB. by Juliane Midori Ikebara (3628970)

“…(O) Graph showing the number of Tunel-positive cells in DG of VA and 2-APB groups. We observed decrease in Tunel-positive cells in rats injected with 2-APB after neonatal anoxia. …”

Image5_Protective effects of YCHD on the autoimmune hepatitis mice model induced by Ad-CYP2D6 through modulating the Th1/Treg ratio and intestinal flora.tif by Jiawen Wu (63886)