Image_2_Differential Regulation of Microglial Activation in Response to Different Degree of Ischemia.tif by Hao Gao (154820)

“…Multiple microglia-related genes such as Cxcl10, Tlr7, Cd86, Tnfrsf1a, Nfkbia, Tgfb1, Ccl2 and Il-6, were upregulated with prolonged ischemia. …”

Epigenetic Modulations in Activated Cells Early after HIV-1 Infection and Their Possible Functional Consequences by Juliana T. Maricato (295063)

“…In addition, activated cells infected by HIV-1 showed lower CD69 expression and a decrease of IL-2, IFN-γ and metabolism-related factors transcripts indicating a possible functional consequence towards global transcriptional repression found in HIV-1 infected cells. …”

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Additional examples—Boundary vector cells. by Lear Cohen (15353793)

rNMP incorporation frequency of Pol γ and the mtDNA replisome on long DNA templates. by Josefin M. E. Forslund (5043218)

Adaptation on a smooth Gaussian fitness landscape by Bjørn Østman (483796)

“…<p>Population of 2304 individuals evolving on a two-dimensional Gaussian fitness landscape. Mutation rate is 0.5 per generattion. …”

Table_2_The Phylosymbiosis Pattern Between the Fig Wasps of the Same Genus and Their Associated Microbiota.XLSX by Jiaxing Li (113609)

“…Moreover, we found that the endosymbiotic Wolbachia carried by fig wasps led to a decrease in bacterial diversity of host-associated microbial communities. …”

Table_2_cpubi4 Is Essential for Development and Virulence in Chestnut Blight Fungus.XLSX by Qi Chen (144168)

“…A total of 378 sites in 236 proteins were identified to be significantly decreased in ubiquitination in the absence of cpubi4. …”

Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics by Farah H. Bardai (6107924)

“…We find that either increasing or decreasing the level of fly Lrrk enhances tau neurotoxicity, which is further exacerbated by expressing Lrrk with dominantly acting Parkinson disease—associated mutations. …”

IGF-1 induces an increase in <i>PRNP</i> expression through the PI3K-Akt-FOXO3a pathway. by Ting Liu (45625)

“…(C) and (D) Western blotting showing the relationship between the phosphorylation of FOXO3a and <i>PRNP</i> expression. Treatment with 50 and 100 ng/ml IGF-1 remarkably increased the phosphorylation of FOXO3a in both the SH-SY5Y and HeLa cell lines but caused little variation in the total level of FOXO3a. …”

Assessment of a strategy combining ambulatory blood pressure, adherence monitoring and a standardised triple therapy in resistant hypertension by Erietta Polychronopoulou (11082142)

“…We evaluated the efficacy of an antihypertensive management strategy combining a standardised therapy with three long acting drugs and electronic monitoring of drug adherence in patients with apparent resistant hypertension.…”

Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs by Kevin J. Paik (3180762)

“…However, under normoxic conditions, HIF-1α is hydroxylated by prolyl hydroxylase 2, and subsequently degraded, with a biological half-life of less than five minutes. …”

DataSheet1_Individuals carrying the HLA-B*15 allele exhibit favorable responses to COVID-19 vaccines but are more susceptible to Omicron BA.5.2 and XBB.1.16 infection.pdf by Lingxin Meng (1647838)

“…</p>Methods<p>Sequential blood samples were continuously collected at different time points from 252 volunteers who were received the CanSino Ad5-nCoV (n= 183) vaccine or the Sinovac CoronaVac inactivated vaccine (n= 69). …”

Table_2_Are Cognitive Changes in Hereditary Spastic Paraplegias Restricted to Complicated Forms?.DOCX by Laís Alves Jacinto-Scudeiro (6730991)

“…</p><p>Results: Fifty four patients with genetically confirmed HSP diagnosis, 36 with spastic paraplegia type 4 (SPG4), 5 SPG11, 4 SPG5, 4 cerebrotendinous xanthomatosis (CTX), 3 SPG7 and 2 SPG3A, and 10 healthy, unrelated control subjects, with similar age, sex, and education participated in the study. …”

Time series of validations on buses using <i>smart-cards</i> during the COVID-19 pandemic period in 2020. by Jorge L. B. Araújo (20324246)

“…<p>The solid curve corresponds to the ratio (<i>V</i> − <i>V</i>₀)/<i>V</i>₀, where <i>V</i> is the number of weekly validations and <i>V</i>₀ is a baseline given by the time average in the period [01–03-2020, 01–13-2020]. …”

Image_2_Reduced Interhemispheric Coherence in Cerebellar Kainic Acid-Induced Lateralized Dystonia.EPS by Elena Laura Georgescu Margarint (9671384)

“…The results showed a progressive interhemispheric coherence decrease in low-frequency bands (delta, theta, beta) during the first 3 days. …”

Do changes in size class compositions influence American alligator spatial distributions? (pt. 2) by Abby Lawson (750688)

“…The decrease in juvenile size classes we detected may reflect reduced reproductive activity mediated by removal of adults through harvest programs. …”

No differences in apoptotic cell death in postnatal interneurons at P0 or P7 of Fgfr1 mutant mice. by Karen Müller Smith (613941)

OSM activates ERK-1/2, SAPK/JNK-1/2 MAP kinases, the PI3-kinase Akt and STAT1/3 in HCT116 cells and STAT3 activation is dependent of the LIFR. by Florian Beigel (174724)

“…<p>(A) Stimulation with OSM (100 ng/mL) resulted in increased phosphorylation of ERK-1/2, SAPK/JNK-1/2 kinases and induced PI3 kinase-dependent Akt phosphorylation. …”

Molecular mechanism underlying anticancer activity of CPGF NPs. by Kirtee D. Wani (636463)