Cooperation of Sumoylated Chromosomal Proteins in rDNA Maintenance by Yoshimitsu Takahashi (270156)

“…Upon characterization of sumoylated proteins involved in rDNA maintenance, we established that Top1p and Top2p, which are sumoylated by Siz1p/Siz2p, most likely collaborate with substrates of Mms21p to maintain rDNA integrity. …”

S1_Figure.pdf by George Brooks (21579206)

“…We observed no age-associated changes in coupling efficiency (ADP:O) of mitochondrial reticulum preparations, but respiratory control (RCR) was decreased in older mice. …”

Image1.PDF by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

Suitability of <i>Taxodium distichum</i> for Afforesting the Littoral Zone of the Three Gorges Reservoir by Bo Li (112195)

“…To explore an effective way to promote biodiversity and associated ecosystem services, we examined <i>Taxodium distichum</i> as a species for afforesting the littoral zone. …”

Table1.XLSX by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

Table3.XLSX by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

Table4.XLSX by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

KCNQ Channels Show Conserved Ethanol Block and Function in Ethanol Behaviour by Sonia Cavaliere (116850)

“…We show that the single KCNQ channel in <em>Drosophila</em> (dKCNQ) has similar electrophysiological properties to neuronal KCNQ2/3, including conserved acute sensitivity to ethanol block, with the fly channel (IC₅₀ = 19.8 mM) being more sensitive than its mammalian ortholog (IC₅₀ = 42.1 mM). …”

<em>C. elegans</em> Mutant Identification with a One-Step Whole-Genome-Sequencing and SNP Mapping Strategy by Maria Doitsidou (237951)

“…We find that the molecular lesion resides in the Pax-6/Eyeless ortholog <em>vab-3</em>. …”

Critical dynamics in <i>E. coli</i> using canalizing functions. by Enrique Balleza (271587)

“…Note that <i>M</i>(<i>x</i>) remains critical even for <i>f_c</i>≈0.66, but it starts to deviate from criticality towards the ordered region for <i>f_c</i>>0.7 (dotted dashed curves). (b) We decreased the value of <i>f_c</i> by removing canalizing functions from the 421 genes which originally are regulated by canalizing functions just by chance (most of them with <i>K</i> = 2 and <i>K</i> = 3). …”

The Impact of Phenotypic and Genetic Heterogeneity on Results of Genome Wide Association Studies of Complex Diseases by Mirko Manchia (423673)

“…Next, we analyzed the Wellcome Trust Case-Control Consortium (WTCCC) data for diabetes mellitus (DM) type 1 (T1D) and type 2 (T2D), using varying proportions of each type of diabetes in order to examine the impact of heterogeneity on the strength and statistical significance of association previously found in the WTCCC data. …”

Table_1_Modelling the Role of Temperature-Induced Environmental Noise on Phytoplankton Niche Dynamics.docx by Subrata Sarker (13148127)

“…Niche overlapping between species decreased significantly with the increase in environmental noise (R² = 0.95). …”

Optimizing Dietary Restriction for Genetic Epistasis Analysis and Gene Discovery in <em>C. elegans</em> by William Mair (9380)

“…In contrast to previous reports, we find that DR can robustly extend the lifespan of worms lacking the AMP-activated protein kinase catalytic subunit AAK2 or the histone deacetylase SIR-2.1, highlighting the importance of first optimizing DR to identify universal regulators of DR mediated longevity.…”

Supplementary Material for: Cerebral Blood Flow Measured by Phase-Contrast Magnetic Resonance Angiography in Preterm and Term Neonates by Wagenaar N. (5463431)

“…<b><i>Background:</i></b> Preterm infants show a decreased tortuosity in all proximal segments of the cerebral vasculature at term-equivalent age (TEA). …”

Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production by Jacob Hodge (2699521)

“…</p> <p>Bio-Block ASCs exhibited ~2-fold higher proliferation than spheroid and Matrigel groups, with senescence reduced 30–37% and apoptosis decreased 2–3-fold. …”

Specific Matrix Metalloproteinases Play Different Roles in Intraplaque Angiogenesis and Plaque Instability in Rabbits by Xiao Qiong Liu (631530)

“…From weeks 4 to 12, the expression of MMP-1, -2, -3, and -9 and vascular endothelial growth factor A (VEGF-A) increased with atherosclerotic plaque development in the abdominal aorta, while the expression of MMP-14 substantially decreased. …”

Verbal Swearing Attenuates the Effects of Social Pain by Michael Philipp (476797)

“…Given the considerable overlap between social and physical pain, it was expected that swearing would be similarly effective in reducing the physical and psychological effects of social pain. We used a 2 (exclusion-prime) x 2 (swearing) independent groups design, operationalising swearing and physical pain in a manner similar to Stephens and Umland (2012). …”

Data_Sheet_1_Short- and Long-Term Effectiveness of Coral Disease Treatments.PDF by Karen L. Neely (6716663)

“…In 2019, in-water disease intervention strategies were implemented to treat affected corals. Two treatment strategies were employed: (1) topical application of an amoxicillin paste directly to disease margins, and (2) application of a chlorinated epoxy to disease margins as well as an adjacent “disease break” trench. …”

Loss of neuronal βPix isoforms impairs neuronal morphology in the hippocampus and causes behavioral defects by Younghee Kwon (1823413)

“…Loss of the neuronal βPix isoforms leads to reduced activity of Rac1 and Cdc42, decreased dendritic complexity and spine density, and increased GluN2B and Ca²⁺/calmodulin-dependent protein kinase IIα expression in the hippocampus. …”

Supplementary Material for: High-Conductance Channel Formation in Yeast Mitochondria is Mediated by F-ATP Synthase e and g Subunits by Carraro M. (5957441)

“…In this study, we investigated the role of F-ATP synthase subunits e, g and b in PTP formation. …”