Diurnal Cycle of Human Thermal Comfort in Maceió-AL by Helen da Silva Mendonça (10393432)

Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway by Stéphanie Duhamel (2699008)

“…Reduction of Aurora A levels by RNA interference or pharmacological inhibition of MEK1/2 reverts the defect in cytokinesis and decreases the frequency of abnormal cell divisions induced by oncogenic H-Ras^V12. …”

The E2F pathway is activated in 5FU-treated Δ40p53:WTp53 cells. by Cecilia B. Levandowski (11238230)

“…<p><b>(A)</b> RNA-seq data (GSEA) shows that differential E2F2 TF activity characterizes the Δ40p53:WTp53 transcriptional response to 5FU in comparison to WTp53 and WTp53:WTp53. …”

Long-lived acceptor dark states can produce bimodal FRET efficiency distributions, multi-exponential donor excited-state decays, and a decrease in measured average FRET efficiency... by Steven S. Vogel (299330)

Data_Sheet_5_Exploring the active ingredients and pharmacological mechanisms of the oral intake formula Huoxiang Suling Shuanghua Decoction on influenza virus type A based on netwo... by Ruying Tang (14036640)

Effects of linagliptin on cardiovascular and kidney outcomes in people with normal and reduced kidney function: secondary analysis of the CARMELINA randomized trial by Vlado Perkovic (141532)

“…We performed secondary analyses of cardiovascular and kidney outcomes across baseline eGFR categories (≥ 60, 45-<60, 30-<45 and < 30 ml/min/1.73 m²) in CARMELINA, a cardio-renal placebo-controlled outcome trial of the DPP-4 inhibitor linagliptin (NCT01897532).…”

DRLE had a cardioprotective effect. by Lung-Shuo Wang (3391244)

Ca²⁺ supplementation <i>in vitro</i> has no impact on the expression of CD69 by expanded Vγ2⁺ T cells and on the production of some cytokines by expanded huma... by Yusuf Cem Eskiocak (10789281)

Bar chart and logistic regression curve of combined gastrointestinal parasite (GIP) infection prevalence in Nepalese Gurkha recruits who migrated to the UK by year, 2012–2020. by William D. Nevin (17854751)

Image3_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Image1_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Table1_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.DOCX by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Image2_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Bar chart and logistic regression curve of yearly positive <i>S</i>. <i>stercoralis</i> results (both charcoal culture and IgG ELISA), in Nepalese Gurkha recruits who migrated to t... by William D. Nevin (17854751)

Cumulative percentage of positive diagnoses made by light microscopy following FEA concentration, depending on whether one, two or three stool samples were analysed, in Nepalese Gu... by William D. Nevin (17854751)

Data Sheet 1_The GPR4 antagonist NE-52-QQ57 increases survival, mitigates the hyperinflammatory response and reduces viral load in SARS-CoV-2-infected K18-hACE2 transgenic mice.pdf by Xin-Jun Wu (21684740)

“…In this study, we evaluated the effects of a GPR4 antagonist, NE-52-QQ57, in the SARS-CoV-2-infected K18-hACE2 transgenic mouse model. …”

General laboratory tests and specific coagulation test in PCR SARS-CoV-2 positive patients with and without thrombosis. by B. de Laat (12475632)

Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies by Stije J. Leopold (3615638)

“…Lower in-hospital mortality was associated with moderate anaemia (OR 0.87 for a decrease of 10 percentage points in haematocrit [95% CI 0.80–0.95]). …”

Bar chart and logistic regression curve of yearly prevalence of hookworm infection in Nepalese Gurkha recruits who migrated to the UK 2012–2020. by William D. Nevin (17854751)

Bar chart and logistic regression curve of yearly prevalence of <i>T</i>. <i>trichiura</i> ova detection in Nepalese Gurkha recruits who have migrated to the UK 2012–2021. by William D. Nevin (17854751)