DataSheet_1_Remodeling of T Cell Dynamics During Long COVID Is Dependent on Severity of SARS-CoV-2 Infection.pdf by Milena Wiech (111682)

“…However, despite the number of studies on COVID-19, many of them addressed only the severe convalescents or the short-term responses. Here, we performed longitudinal studies of mild, moderate and severe COVID-19-convalescent patients, at two time points (3 and 6 months from the infection), to assess the dynamics of T cells immune landscape, integrated with patients-reported symptoms. …”

Image_5_MiR-451a and let-7i-5p loaded extracellular vesicles attenuate heme-induced inflammation in hiPSC-derived endothelial cells.jpeg by Justin J. Thomas (14292593)

“…This inflammatory response was attenuated by exposure with miR-451a or let-7i-5p-loaded EVs. We also found a decrease in transcription of ICAM1 and P-Selectin, as well as the secretion of key inflammatory cytokines (e.g., CXCL10, TNF-α, and IFN-γ). …”

Changes in net primary PM_2.5 emissions are impacted substantially more by changes in vehicle emissions in comparison to changes in emissions from electric generating uni... by Jaye Mejía-Duwan (15401425)

Downregulation of <i>TcPiezo1</i> expression decreases Ca²⁺ entry in <i>T. cruzi.</i> by Guozhong Huang (673424)

“…<p>Intracellular Ca²⁺ concentrations of 5 × 10⁷ <i>TcPiezo1 Tet-OFF</i> epimastigotes (A-C) or 2 x 10⁷ trypomastigotes (D) expressing jGCaMP7s were measured by jGCaMP7s signal fluorescence in arbitrary units of fluorescence (AU). …”

Sumoylation of Sp1 repressed <i>LEDGF/p75</i> gene transcription by decreasing the abundance of Sp1 to DNA. by Dhirendra P. Singh (164293)

Environmental swabs with Ct values below 38 yielded enough sequence reads to cover a substantial portion of the SARS-CoV-2 genome. by David A. Coil (7382090)

“…<p>The percent of the SARS-CoV-2 reference genome (isolate Wuhan-Hu-1) covered at ≥ 5X decreased steeply as a function of the mean Ct value (using CDC N1, N2, and Berlin RdRP primers). …”

Primary human KIR2DL5⁺ NK cells are inhibited by CD155-expressing target cells. by Pia Fittje (12936621)

Data_Sheet_2_Identification and Computational Analysis of Novel TYR and SLC45A2 Gene Mutations in Pakistani Families With Identical Non-syndromic Oculocutaneous Albinism.docx by Nousheen Bibi (446289)

“…Sequence analysis identified a novel insertion variant (NM_016180.5: c.1331_1332insA) in the SLC45A2. …”

Data_Sheet_2_Identification and Computational Analysis of Novel TYR and SLC45A2 Gene Mutations in Pakistani Families With Identical Non-syndromic Oculocutaneous Albinism.docx by Nousheen Bibi (446289)

“…Sequence analysis identified a novel insertion variant (NM_016180.5: c.1331_1332insA) in the SLC45A2. …”

ISA27 induces the stabilisation of p53 protein levels by decreasing the interaction of p53 with MDM2 in GBM cells. by Barbara Costa (447711)

Enhanced Nrf2 activity decreases fatty acid transport and results in increased fatty acids content in white adipose tissue. by Jialin Xu (40952)

Blockade of kinin B₁R in the chronic disease phase decreased the clinical symptoms and neuroinflammation in the EAE model. by Rafael C. Dutra (205755)

Fig3-5 by Yuki Iwachido (12079661)

Data Sheet 3_Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE.pdf by Mi-Ae Lyu (20413646)

“…</p>Results<p>In a dose-dependent manner, ruxolitinib addition synergizes with UCB-Tregs to suppress SLE-PBMC proliferation, inhibit CD8⁺ T cells, and reduce phosphorylation of STAT3/STAT5/AKT in CD8⁺ T cells. …”

Data Sheet 1_Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE.pdf by Mi-Ae Lyu (20413646)

“…</p>Results<p>In a dose-dependent manner, ruxolitinib addition synergizes with UCB-Tregs to suppress SLE-PBMC proliferation, inhibit CD8⁺ T cells, and reduce phosphorylation of STAT3/STAT5/AKT in CD8⁺ T cells. …”

Impaired glucose metabolism and decreased insulin sensitivity in isolated adipocytes of Nscl-2−/−, Nscl-2−/−×ob/ob mice and controls. by Karen Ruschke (372824)

<i>ogt-1; eel-1 +</i> Pan-neuronal OGT-1 have decreased sensitivity to electroshock and improved locomotion. by Nirthieca Suthakaran (11731101)

“…<p>Shown are each genotype ran through the electroconvulsive seizure assay for 3 seconds at 47V in saline control group. (A) Average time of recovery was significantly decreased in <i>ogt-1; eel-1</i> + Pan-neuronal OGT-1 worms, <i>Ogt-1(ok430) III; eel-1(bgg1) IV; bggSi2[Prab-3</i>::<i>ogt-1a] II</i> (n = 33), in comparison to <i>ogt-1;eel-1</i> double mutants (n = 30) but not significantly different from <i>eel-1</i> null mutants (n = 26). …”

Amino acids 605 and 606 of the PB2 ‘627’ domain are involved in interaction with NP. by Ho-Pan Hsia (4768638)

<i>Cin85</i>-Deficiency results in defective clearance of LCMV-c13 and is correlated with decreased neutralizing antibody titer. by Saravanan Raju (5181014)

Decreased Autophagy in Rat Heart Induced by Anti-β1-Adrenergic Receptor Autoantibodies Contributes to the Decline in Mitochondrial Membrane Potential by Li Wang (15202)

“…Male adult rats were randomized to receive a vehicle or peptide corresponding to the second extracellular loop of the β₁ adrenergic receptor (β₁-AAB group, 0.4 μg/g every two weeks for 12 weeks) and treated with rapamycin (RAPA, an autophagy agonist) at 5 mg/kg/day for two days before detection. …”