Table_5_lnc-REG3G-3-1/miR-215-3p Promotes Brain Metastasis of Lung Adenocarcinoma by Regulating Leptin and SLC2A5.XLS by Chunyang Jiang (3550025)

“…Nude mice xenograft tumors constructed with decreased lnc-REG3G-3-1 confirmed the influences on gene expression in vivo. lnc-REG3G-3-1 was highly expressed in BM tissues that originated from LADC compared with that in primary cancer tissues. lnc-REG3G-3-1 reduced miR-215-3p expression, thereby regulating the target genes leptin and SLC2A5 and the signaling pathways, taking part in the lnc-REG3G-3-1/miR-215-3p axis in the process of BM from LADC. lnc-REG3G-3-1, leptin, and SLC2A5 through regulating signaling pathways may be jointly involved in the regulation of the biological process of BM in patients with LADC.…”

Vasopressin decreased the population fEPSP evoked by stimulation of LIII entorhinal fibers (EC LIII) and recorded in the CA2 dendritic field. by Magda Chafai (295116)

“…C) Left: fEPSP recorded in the presence of the GABA_A antagonist SR 95531. AVP was effective to decrease the fEPSP during LTP (n = 14) but failed to affect the fEPSP in slices in which no LTP was evoked (Middle; n = 7). …”

2-AAPA decreases H/R induced apoptosis in mitoNEET-KD cells and increases mitoNEET-protein despite KD. by Anika Habener (3165984)

“…(B) siRNA transfection decreased mitoNEET-mRNA efficiently in the presence and absence of chemical GSR-inhibitor 2-AAPA (10 μM, n = 5) determined by real-time RT-PCR. …”

Fig 1 - by Marc S. Penn (16624541)

Fig 4 - by Marian Adan (16641634)

HGDP data show that T2D risk allele frequencies decrease from Sub-Saharan Africa through Europe to East Asia. by Rong Chen (29176)

“…A similar pattern was observed in the remaining five T2D risk alleles in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002621#pgen.1002621.s002" target="_blank">Figure S2</a>. …”

<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b> by Denise M. Drotar (21679539)

Decreased levels of NMDAR2B in the synaptic plasma membrane of spinal cord of CCI-mice treated with compound 30 at 56 dpi. by Xavier Xifró (719821)

Image_2_Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2... by Ivan Odak (8677092)

“…In this prospective study of a cohort of 46 SARS-CoV-2 patients infected with the Wuhan strain of SARS-CoV-2 we longitudinally analyzed changes in humoral and cellular immunity upon early and late convalescence. …”

BBX21 negatively regulates <i>ABI5</i> expression by interfering with HY5 binding to the <i>ABI5</i> promoter. by Dongqing Xu (528295)

“…(C) EMSAs showing that increasing amounts of His-BBX21 protein (lanes 2 to 6) decreased the binding of GST-HY5 to the <i>ABI</i>5 promoter.…”

TP compounds suppress tumor growth, decrease cell proliferation and induce caspase 3 cleavage in mouse xenograft models with no systemic toxicities. by Melissa Millard (275631)

“…<p>(A) Graph shows average tumor volumes amongst the treatment groups over the course of the experiment. …”

Decreased disease incubation times in RML prion infected PINK1^KO and Parkin^KO mice. by Anne Ward (334296)

DAT and NAT activity and the effects of MPP(+) on mitochondrial activity in SH-SY5Y cells. by Joanna A. Korecka (415952)

“…Mitochondrial membrane potential was measured with TMRM assay in RA (<b>D</b>) and noRA (<b>E</b>) treated cells under different MPP(+) concentrations. RA cells showed a decrease in membrane potential at 0.1 mM up to 1 mM MPP(+), whereas noRA cells first showed an increase in membrane potential at 0.01 mM MPP(+) followed by a decrease at 0.5 and 1 mM MPP(+). …”

<i>Brn3b</i> deletion reduces the number of Brn3b+ neurons in the superficial SC and decreases projections to LP. by Hyoseo Lee (17419987)

“…<b>(E–G)</b> No obvious differences in axonal projections to the central lateral nucleus of the thalamus (CL), adPBG, Pn, and CnF between control and cKO at P24 (<i>n</i> = 5 mice/group). Scale bars: 250 μm. The data underlying this figure can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002386#pbio.3002386.s015" target="_blank">S1 Data</a>. adPBG, adjacent parabigeminal nucleus; AP, alkaline phosphatase; CnF, cuneiform nucleus; LP, lateral posterior nucleus; Pn, pons; PRC, precommisural nucleus; SC, superior colliculus; vLGN, ventral lateral geniculate nucleus.…”

Presentation_1_Decreased Frequency of Intestinal CD39+ γδ+ T Cells With Tissue-Resident Memory Phenotype in Inflammatory Bowel Disease.PPTX by Jana Libera (7053824)

“…The frequency of CD39⁺ cells among tissue-resident memory LPL (Trm) was higher compared to non-Trm for all subsets, confirming that CD39 is a marker for the tissue-resident memory phenotype. γδ⁺ Trm also showed a distinct cytokine profile upon stimulation – the frequency of IFN-γ⁺ and IL-17A⁺ cells was significantly lower in γδ⁺ Trm compared to non-Trm. Interestingly, we observed a decreased frequency of CD39⁺ γδ⁺ T cells in IBD patients compared to healthy controls (p = 0.0049). …”

Video_3_Decreased anterograde transport coupled with sustained retrograde transport contributes to reduced axonal mitochondrial density in tauopathy neurons.AVI by Anusruti Sabui (13885827)

“…Consistently, axonal mitochondrial abundance is reduced in P301L neurons. We further studied the possible role of two opposing motor proteins on mitochondrial transport and found that mitochondrial association of kinesin is decreased significantly in P301L cells. …”

Video_1_Decreased anterograde transport coupled with sustained retrograde transport contributes to reduced axonal mitochondrial density in tauopathy neurons.AVI by Anusruti Sabui (13885827)

“…Consistently, axonal mitochondrial abundance is reduced in P301L neurons. We further studied the possible role of two opposing motor proteins on mitochondrial transport and found that mitochondrial association of kinesin is decreased significantly in P301L cells. …”

TGFβ1 decreases p27 phosphorylation at Thr187 in the gastric mucosa of 14-day-old rats during fasting. by Ana P. Z. P. Fiore (593811)

Periodic Trends for Transition Metal Dihydrides MH₂, Dihydride Dihydrogen Complexes MH₂·H₂, and Tetrahydrides MH₄ (M = Ti, V, and Cr) by Buyong Ma (31206)

“…Comparison between the present work and experimental IR spectra from the matrix isolation of the cocondesation of transition metal atoms (Ti, V, and Cr) with H₂ molecules confirmed the existence of CrH₂·H₂ by identifying a strong unique absorption at 1510 cm^-1. …”

DCB-3503 did not decrease mRNA levels of cyclin D1, survivin, β-catenin, p53, and p21. by Ying Wang (11406)