Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination by Tongchao Li (115391)

“…Mouse UBR3 poly-ubiquitinates Kif7, the mammalian homologue of Cos2. Finally, loss of UBR3 up-regulates Kif7 protein levels and decreases Hh signaling in cultured cells. …”

Pharmacodynamic and pharmacokinetic properties of BPN-14136 in cynomolgus monkey and beagle dog. by Boglarka Racz (1336803)

High SMAD7 and p-SMAD2,3 expression is associated with environmental enteropathy in children by Sana Syed (4591699)

“…Environmental enteropathy (EE) is an acquired inflammatory disease of the small intestine (SI), which is associated with linear growth disruption, cognitive deficits, and reduced oral vaccine responsiveness in children <5 y in resource-poor countries. We aimed to characterize EE inflammatory pathways by determining SMAD7 and p-SMAD2,3 levels (using Western blotting) in EE duodenal biopsies (N = 19 children, 7 from Pakistan, 12 from Zambia) and comparing these with healthy controls (Ctl) and celiac disease (CD) patients from Italy. …”

Table 5_Integrated analysis of microbiome and metabolome reveals insights into cervical neoplasia aggravation in a Chinese cohort.xlsx by Qingzhi Zhai (21265412)

“…Furthermore, we found a significant correlation between the cervical microbiota Porphyromonas and the metabolite PGE2, suggesting a potential role of key microbiota in inducing inflammation.…”

Table1_Photosynthetic Production Determines Bottom Water Oxygen Variations in the Upwelling Coastal South China Sea Over Recent Decades.docx by Xiaowei Zhu (24440)

“…The ratio records showed oscillations in varying degrees and exhibited no clear trends before ∼1980s, after which, however, there occurred a persistent decreasing trend or basically remained at lower values. …”

RT-qPCR evaluation of MYD88, NLRP3, and NFκβ in GA 18.5 pup brains. by Adrienne J. Bradley (20861948)

RSV infection in Nb<i>ATG3</i> and Nb<i>ATG5</i>-silenced <i>N</i>. <i>benthamiana</i>. by Xiangxiang Zhang (498122)

“…<p><b>(A)</b> Silencing of Nb<i>ATG3</i> and Nb<i>ATG5</i> individually did not cause obvious phenotypes in <i>N</i>. …”

ERK activity of lung epithelial cysts in Fig 2A. by Hisako Takigawa-Imamura (3175320)

Experimental tracings obtained during a breath from patient receiving PSV (pressure support 5 cmHO) by Andrea Aliverti (20592)

Table_1_Staff SARS-CoV-2 Seroprevalence and Mental Health as Key Factors in University Response to COVID-19 Pandemic.pdf by David G. Lopes (10977273)

“…<p>Background: In response to rapid global spread of the newly emerged coronavirus disease 2019 (COVID-19), universities transitioned to online learning and telework to decrease risks of inter-person contact. To help administrators respond to the COVID-19 pandemic and better understand its impacts, we surveyed SARS-CoV-2 seroprevalence among NOVA University employees and assessed community mental health.…”

Image1_High Expression of ATP6V1C2 Predicts Unfavorable Overall Survival in Patients With Colon Adenocarcinoma.TIF by Guanghua Li (1415437)

“…We also found that high expression of ATP6V1C2 could decrease pathway activity of CD8 T effector implicated in tumor microenvironment (TME). …”

<i>In Silico</i> Identification and <i>In Vitro</i> and <i>In Vivo</i> Validation of Anti-Psychotic Drug Fluspirilene as a Potential CDK2 Inhibitor and a Candidate Anti-Cancer Drug by Xi-Nan Shi (765399)

“…In this study, we utilized our free and open-source protein-ligand docking software, idock, prospectively to identify potential CDK2 inhibitors from 4,311 FDA-approved small molecule drugs using a repurposing strategy and an ensemble docking methodology. …”

Flow chart. by Luther Dogbla (21410142)

“…Age was associated with a decrease in the propension of consulting for the three lockdown periods (p < 0.001). …”

<i>CSN5</i> or <i>Nedd8</i> mutations have a diverse effect on dendritic branching. by Inna Djagaeva (369627)

“…(B) In <i>CSN5^N</i> mutants, ddaC neurons frequently show decreased dendritic branching. …”

Validation of hTERT mRNA as a direct target of miR-512-5p in CNE cells. by Jun Li (6494)

“…(B) MiR-512-5p resulted in a significant decrease in luciferase expression in hTERT-3’UTR transfected cells compared with the scramble, while MiR-512-5p caused no statistical change in luciferase expression in mut-hTERT-3’UTR compared with the scramble(C) miR-512-5p mimic led to down-regulation of hTERT and TRF2 in CNE cells. …”

Inhibition of myoblast differentiation by miR-451a. by Rachel Munk (344556)

Engorged or gravid female <i>Phlebotomus spp</i>. tested^a (N = 249) and infected (n = 25) with <i>Leishmania spp</i>. during the baseline survey and in the pre- and post... by Samer Sawalha (5890535)

Response of I_Ca,L to IBMX in WT and AMPKα2-/- mice AVMs. by Anne Garnier (130125)

Proportion of time spent in the Start Room or Avoidance Room or showing a behaviour (Stimulus Contact) presented across stimuli and separately for piglets and gilts. by Sara Hintze (3216885)

Fig 2 - by Daisuke Kume (14312076)