Table_1_Real-world impact of the introduction of chemo-immunotherapy in extended small cell lung cancer: a multicentric analysis.docx by Laura Bonanno (3524183)

“…Estimated PFS and OS were significantly longer in patients treated after May 2020 with hazard ratio (HR) for PFS and OS of 0.61 (95% CI: 0.46-0.81, p < 0.001) and 0.70 (95% CI: 0.52-0.93, p = 0.015), respectively. 6-month PFS rate increased from 27% to 40% (p = 0.04) while 12-months PFS raised from 1% to 11% (p = 0.003). 12-month and 18-month OS rate increased from 15% to 28% (p = 0.03) and from 2.1% to 12% (p = 0.009), respectively. After May 2020 the median number of hospitalization days per patient decreased significantly and the incidence of severe AEs was similar. …”

Image_1_Real-world impact of the introduction of chemo-immunotherapy in extended small cell lung cancer: a multicentric analysis.jpeg by Laura Bonanno (3524183)

“…Estimated PFS and OS were significantly longer in patients treated after May 2020 with hazard ratio (HR) for PFS and OS of 0.61 (95% CI: 0.46-0.81, p < 0.001) and 0.70 (95% CI: 0.52-0.93, p = 0.015), respectively. 6-month PFS rate increased from 27% to 40% (p = 0.04) while 12-months PFS raised from 1% to 11% (p = 0.003). 12-month and 18-month OS rate increased from 15% to 28% (p = 0.03) and from 2.1% to 12% (p = 0.009), respectively. After May 2020 the median number of hospitalization days per patient decreased significantly and the incidence of severe AEs was similar. …”

Network of the downregulated proteins present in _sEVs-IC and the miRs from WL-IC that might regulate them. by María-Angélica Calderón-Peláez (2851865)

RSK functions as a Ca²⁺ independent kinase to increase force and RLC₂₀ phosphorylation. by Mykhaylo Artamonov (389145)

DataSheet1_Lifestyle Modifies the Diabetes-Related Metabolic Risk, Conditional on Individual Genetic Differences.docx by Jisu Shin (4489474)

“…<p>Metabolic syndrome is a group of heritable metabolic traits that are highly associated with type 2 diabetes (T2DM). Classical interventions to T2DM include individual self-management of environmental risk factors, such as improving diet quality, increasing physical activity, and reducing smoking and alcohol consumption, which decreases the risk of developing metabolic syndrome. …”

Uncovering Direct Targets of MiR-19a Involved in Lung Cancer Progression by Kumiko Yamamoto (795440)

“…To evaluate these genes as direct miR-19a target genes, we performed luciferase, pull-down, and western blot assays. …”

The study population demographic characteristics. by Abubakr Abdalla Mohammed Alhaj (18536769)

“…Mycetoma was painful in 21%, and a family history of mycetoma was recorded in 11.5% of patients. …”

Patients characteristics raw data. by Abubakr Abdalla Mohammed Alhaj (18536769)

“…Mycetoma was painful in 21%, and a family history of mycetoma was recorded in 11.5% of patients. …”

Showing massive head and neck actinomycetoma. by Abubakr Abdalla Mohammed Alhaj (18536769)

“…Mycetoma was painful in 21%, and a family history of mycetoma was recorded in 11.5% of patients. …”

Ambient Temperature Activation of Haloporphyrinic-Enediynes:  Electronic Contributions to Bergman Cycloaromatization by Mahendra Nath (2695399)

“…We have synthesized the nickel(II) 2,3-bis(haloethynyl)-5,10,15,20-tetraphenylporphyrins with −Br (<b>2a</b>) or −I (<b>2b</b>) at the alkyne termini position from the corresponding 2,3-diethynyl analogue (<b>1</b>). …”

DataSheet2_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic resp... by Hui Jia (638620)

“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. …”

Deferiprone down-regulates Omniscan-induced CD163⁺ cells in NSF skin as shown by immunohistochemistry (Panel A). by Chhanda Bose (787135)

Williams et al. - Consumption of rodenticide baits by invertebrates as a potential route into the diet of insectivores - field data and pilot data by Emily Williams (17655642)

Nasopharyngeal Carriage of Pneumococci Four Years after Community-Wide Vaccination with PCV-7 in The Gambia: Long-Term Evaluation of a Cluster Randomized Trial by Anna Roca (118568)

“…<div><p>Background</p><p>A village-randomized trial of a seven-valent pneumococcal-conjugate-vaccine (PCV-7) conducted in rural Gambia showed a decrease of vaccine-type (VT) and a non-significant increase in non-vaccine-type (NVT) nasopharyngeal carriage of pneumococci two years after vaccination. …”

Supplementary Material for: Association between serum albumin to creatinine ratio and readmission in elderly heart failure patients: A Retrospective Cohort Study by Guo L. (3722611)

“…After adjusting for potential confounders, we found that for each unit increase in sACR, the 28-day readmission rate decreased by 48% (OR = 0.52, 95% CI: 0.29-0.95, P = 0.003). …”

Implementation of a behaviour change campaign to promote positive household water treatment behaviours in earthquake-affected areas of rural Nepal by Karen Joe (11580280)

Supplementary Material for: Body mass index and all-cause mortality in elderly patients with percutaneous coronary intervention: A meta-analysis by Wang Y. (2884271)

A Genetic Screen for Dihydropyridine (DHP)-Resistant Worms Reveals New Residues Required for DHP-Blockage of Mammalian Calcium Channels by Trevor C. Y. Kwok (46148)

“…Ca_v1 channels normally exist in three states: a resting closed state, an open state that is triggered by membrane depolarization, followed by a non-conducting inactivated state that is triggered by the influx of calcium ions, and a rapid change in voltage. …”

Supplementary Material for: Feasibility, efficacy and safety of peripheral venous access for chronic double-filtration plasmapheresis with regional citrate anticoagulation by Cardinale A. (16526823)

“…Results: Among the 22 patients included (64% men), 7 patients (32%) were classified as primary failures (2 patient refusals, 5 inadequate PVAs), 1 patient (5%) as a secondary failure (due to uncomfortable venipunctures), and 14 patients (64%) as successful. …”

Attitudes and Personal Attributes Regarding Patient Receptivity towards the Participation of Medical Students in Gynecological Consultations: A Cross-Sectional Study by Miriam da Silva Wanderley (5380001)

“…The comfort level with the presence of a student was strongly related to the number of students present during the consultation (Cramér V=0.671). …”