Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity by Lauar de Brito Monteiro (12288661)

“…Leptin levels are increased in obesity. Here, we show that leptin enhances the effects of LPS in macrophages, intensifying the production of cytokines, glycolytic rates and morphological and functional changes in the mitochondria through an mTORC2-dependent, mTORC1-independent mechanism. …”

Table_2_TAZ is involved in breast cancer cell migration via regulating actin dynamics.docx by Hong Seok Choi (121525)

“…Furthermore, myosin light chain kinase (MLCK) and phosphorylated MLC2 were significantly decreased in MDA-MB-231 cells with TAZ knockdown, inhibiting the assembly of stress fibers and focal adhesions.…”

Data Sheet 2_Mepolizumab treatment alters the functional phenotype of eosinophils in severe eosinophilic asthma.pdf by Pablo Miguéns-Suárez (22695716)

Image 2_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif by Stefanie Wagner (743707)

“…Standard 16S rRNA gene amplicon sequencing of microbiota samples offers compositional data in relative, but not absolute abundancies, and the presence of multiple copies of 16S rRNA genes in bacterial genomes introduces bias into compositional data. We explored whether improved sequencing data analysis influences the significance of the effect exerted by antibiotics on the faecal microbiota of young pigs using two veterinary antibiotics. …”

Image_2_Mycobacterium tuberculosis Rv0309 Dampens the Inflammatory Response and Enhances Mycobacterial Survival.jpeg by Yongchong Peng (8583357)

Image_2_NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes.jpeg by Kathryn W. Juchem (11940605)

S1P1, S1P3, and PKCβII protein expression analysis of CMECs. by Zhiyong Yin (311496)

“…<p>Compared with control, we detected a significant decrease of S1P1 and increase of PKCβII in HG group. …”

Covalently Immobilized Nickel Nanoparticles Reinforce Augmentation of Mass Transfer in Millichannels for Two-Phase Flow Systems by Pooja Jaiswal (11831979)

Introduction to Ecology; A study on hair colour and gender by Jenna Braun (2888243)

Image 2_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.pdf by Bar Piscon (20906495)

“…Nevertheless, Gram-negative Enterobacteriaceae species inhabiting the intestinal tract of mammals are considered to be more bile-resistant compared to Gram-positive bacteria and are thought to tolerate high bile concentrations.</p>Results<p>Here, we show that 1-2% of GCA inhibit the growth of Enterobacteriaceae species, including E. coli, Salmonella enterica. …”

Table_2_Impact of oestrus synchronization devices on ewes vaginal microbiota and artificial insemination outcome.XLSX by Edgar L. Reinoso-Peláez (14829628)

“…</p>Methods<p>In this study, we analyzed the vaginal microbiome of 94 vaginal swabs collected from 47 ewes with alternative treatments applied to the progesterone-releasing intravaginal devices (probiotic, maltodextrin, antibiotic and control), in two sample periods (before placing and after removing the devices). …”

Participant characteristics. by Ronald Kusolo (13200268)

“…The risk factor prevalences that decreased significantly were: inadequate physical activity from 5.0% in 2014 to 3.6% in 2023 (p=0.003), and current smoke tobacco use from 9.6% in 2014, to 8.3% in 2023 (p= 0.046). …”

Image 2_The gut microbiota in liver transplantation recipients during the perioperative and postoperative recovery period.jpeg by Zhongyuan Bai (8859077)

“…Metagenomic sequencing, analyzed using the LEfSe method, identified a total of 50 genera that played significant roles in this process. …”

Imidazo[1,2-a]quinoxaline inhibits proliferation by Liyuan Luo (10997496)

“…Viabilities of LN229 and C6 cells was decreased to 24 and 29%, respectively on treatment with 50 μM IMQ. …”

Image_2_Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response.pdf by Fernanda Rosa (4801314)

“…To address this knowledge gap, 21-day-old germ-free mice (C57BI/6) were orally gavaged with 15 mg/day of pooled HMOs for 7 or 14 days and euthanized at day 28 or 35. A set of mice was maintained until day 50 to determine the persistent effects of HMOs. …”

Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome by Christopher S. Ward (405858)

“…Both male and female mice possessing <i>Mecp2</i> mutations show a decrease in urine output per micturition event. …”

Cilia disassembly proceeds at a faster rate in CCDC66-depleted cells, which is regulated by the AurkA-HDAC6 axis and rescued by microtubule stabilization. by Jovana Deretic (13113617)

“…Cilia length was quantified in 3D according to ARL13b signal (co-localizing with acetylated-tubulin). The mean cilia length in CCDC66-depleted cells decreased to 0.74-fold compared to the mean control length at 0 h. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

Data Sheet 2_To VR or not to VR: assessing cybersickness in navigational tasks at different levels of immersion.pdf by Luis Eudave (11939843)

“…Despite the growing use of VR in research, there is a lack of consensus on the most effective methods for measuring cybersickness across different experimental modalities and over time. Here, we compared two cybersickness assessment tools: the widely-used Simulator Sickness Questionnaire (SSQ) and the more recent Cybersickness in VR Questionnaire (CSQ-VR). …”