Image_2_Phosphorylation of Glutamine Synthetase on Threonine 301 Contributes to Its Inactivation During Epilepsy.TIF by Deborah Huyghe (6717023)

power-hop exponent <i>h</i> for two different types of the BA preferential attachment networks. by Evangelos Papalexakis (3180489)

The Heteromultimeric Debranching Enzyme Involved in Starch Synthesis in Arabidopsis Requires Both Isoamylase1 and Isoamylase2 Subunits for Complex Stability and Activity by Maria Sundberg (464836)

“…Here we use TAP (tandem affinity purification) tagging to provide direct evidence in Arabidopsis that ISA1 interacts with its homolog ISA2. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

Gonadal development and sex ratios as a function of TL. by Frederic H. Martini (481487)

“…</p> <p>(b) Sex ratios (female:male) as a function of TL. Data were sorted into 50 mm TL intervals. …”

High-Throughput Screening for Novel Inhibitors of <em>Neisseria gonorrhoeae</em> Penicillin-Binding Protein 2 by Alena Fedarovich (134557)

“…This assay was used to screen a 50,000 compound library for potential inhibitors of <em>N. gonorrhoeae</em> PBP 2, and 32 compounds were identified that exhibited >50% inhibition of Bocillin-FL binding to PBP 2. …”

DataSheet2_Comprehensive Transcriptome Sequencing Analysis of Hirudinaria manillensis in Different Growth Periods.docx by Huiquan Shan (12627700)

“…Moreover, in the adult stages, a significant increase in the expression of the Hirudin-HM (HIRM2) genes was detected. In addition, our comparative transcriptome profiling data from different growth stages of H. manillensis also identified a large number of DEGs and DElncRNAs which were tentatively found to be associated with the growth of H. manillensis; as it grew, the muscle-related gene expression increased, while the lipid metabolism and need for stimulation and nutrition-related genes decreased. …”

DataSheet_1_The isl2a transcription factor regulates pituitary development in zebrafish.xlsx by Chen-Yan Yan (14577641)

“…</p>Methods<p>We used the CRISPR/Cas9 system to successfully establish homozygous ISL2-orthologue (isl2a and isl2b) knockout zebrafish. …”

Raw images. by Dahae Lee (3125157)

“…PA significantly decreased lipid levels in HepG2 cells, which was prevented by PPD, Rg1, Rb2, and Rg3. …”

DataSheet_1_Novel HYDIN variants associated with male infertility in two Chinese families.docx by Hui Yu (27723)

“…ICSI was applied to assist the mutational patient to achieve offspring.</p>Result<p>We identified two HYDIN compound heterozygous variants. …”

image_2_The Increased Endogenous Sulfur Dioxide Acts as a Compensatory Mechanism for the Downregulated Endogenous Hydrogen Sulfide Pathway in the Endothelial Cell Inflammation.jpeg by Da Zhang (598052)

“…In our present study, we aimed to investigate the effect of endogenous H₂S on the SO₂ generation in the endothelial cells and explore its significance in the endothelial inflammation in vitro and in vivo. …”

image_1_The Increased Endogenous Sulfur Dioxide Acts as a Compensatory Mechanism for the Downregulated Endogenous Hydrogen Sulfide Pathway in the Endothelial Cell Inflammation.jpeg by Da Zhang (598052)

“…In our present study, we aimed to investigate the effect of endogenous H₂S on the SO₂ generation in the endothelial cells and explore its significance in the endothelial inflammation in vitro and in vivo. …”

Table_1_The global, regional and national burden of type 2 diabetes mellitus in the past, present and future: a systematic analysis of the Global Burden of Disease Study 2019.docx by Junjun Ye (13492591)

“…</p>Methods<p>The main data source was the Global Burden of Disease 2019 database. We assessed the changes in T2DM burden from 1990 to 2019 with joinpoint regression analysis. …”

Image_5_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.pdf by Mudit Chowdhary (6016496)

“…Median follow-up time was 62.2 months. On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Table_1_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.DOCX by Mudit Chowdhary (6016496)

“…Median follow-up time was 62.2 months. On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Image_4_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.pdf by Mudit Chowdhary (6016496)

“…Median follow-up time was 62.2 months. On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Image_3_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.pdf by Mudit Chowdhary (6016496)

“…Median follow-up time was 62.2 months. On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Image_1_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.pdf by Mudit Chowdhary (6016496)

“…Median follow-up time was 62.2 months. On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Table2_Regulation of feeding dynamics by the circadian clock, light and sex in an adult nocturnal insect.DOCX by Evan Force (17758557)