Table_1_Clinical and immunological features of an APLAID patient caused by a novel mutation in PLCG2.xls by Qi Peng (702503)

“…Background<p>The APLAID syndrome is a rare primary immunodeficiency caused by gain-of-function mutations in the PLCG2 gene. We present a 7-year-old APLAID patient who has recurrent blistering skin lesions, skin infections in the perineum, a rectal perineal fistula, and inflammatory bowel disease.…”

Splicing assays of wt and mutant pre-mRNA in the absence and presence of wild-type StpA and mutant G126V-StpA by Rupert Grossberger (9105)

“…The reactions were performed in the presence of 5 mM MgCl, 0.5 mM GTP, 50 mM Tris–HCl (pH 7.3) and 0.4 mM spermidine (see Materials and Methods). () Splicing of the wt intron pre-RNA without added protein (full circles), with the addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). () Splicing of the C865U pre-RNA intron mutant without protein (full circles), with addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). …”

Table_2_Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma.XLSX by Kshama Gupta (8799284)

“…To assess longevity of radiation effects, we compared survival with implantation occurring 2 months vs. 24 hrs following radiation, finding worse survival in animals implanted at 2 months. …”

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults by Carrie V. Breton (74382)

“…For example, a 2 SD increase in prenatal PM_2.5 was associated with CAS indices, including a 5% increase (β = 1.05, 95% CI 1.00–1.10) in carotid stiffness index beta, a 5% increase (β = 1.05, 95% CI 1.01–1.10) in Young’s elastic modulus and a 5% decrease (β = 0.95, 95% CI 0.91–0.99) in distensibility. …”

Table 3_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 4_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 6_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 5_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Image_2_Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia.TIF by Bárbara Guimaraes de Freitas (7408151)

“…Here, we showed that a single morphine subcutaneous injection induces analgesia followed by a long-lasting delayed hyperalgesia in uninjured and PGE2 sensitized rats. …”

Image_2_Abnormal Static and Dynamic Functional Connectivity in Left and Right Temporal Lobe Epilepsy.pdf by Xiaomin Pang (11921240)

Table_2_Multiple omics revealed the growth-promoting mechanism of Bacillus velezensis strains on ramie.xlsx by Xin Wang (91924)

Image_2_Antibiotic-Induced Disruption of Gut Microbiota Alters Local Metabolomes and Immune Responses.JPEG by Lin Sun (105539)

Image_2_Destination and Specific Impact of Different Bile Acids in the Intestinal Pathogen Clostridioides difficile.TIFF by Nicole G. Metzendorf (6371615)

“…However, the basis and the molecular action of bile acids (BAs) on the pathogen are not well understood. We stressed the pathogen with the four most abundant human bile acids: cholic acid (CA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA) and lithocholic acid (LCA). …”

Image 2_Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19.jpeg by Aurelie Guironnet-Paquet (15407171)

“…</p>Results<p>As expected, performing TPE decreased the amount of anti-type I IFN auto-antibodies and improved the elimination or limited the production of certain inflammatory mediators (IL-18, IL-7, CCL2, CCL3, etc.) circulating in the blood of COVID-19 patients, compared to ST controls. …”

Image_2_The effectiveness of a brief video-based intervention in reducing gender bias in Korea.pdf by Yejin Bae (17832138)

“…The findings highlight the possibility of utilizing short video intervention that enhances perspective taking on decreasing gender bias.</p>…”

Table_2_Photosynthesis in Ranunculus asiaticus L.: The Influence of the Hybrid and the Preparation Procedure of Tuberous Roots.docx by Petronia Carillo (4890955)

“…The quantum yield of PSII (ϕ_PSII), electron transport rate (ETR) and non-photochemical quenching (NPQ) did not differ between the two hybrids. The maximal photochemical efficiency (Fv/Fm) was higher in MBO than in MDR and showed a decrease in both hybrids after vernalization. …”

Image_2_Metagenomic analysis demonstrates distinct changes in the gut microbiome of Kawasaki diseases children.pdf by Linli Han (19186516)

DataSheet2_Estimation of the P Fertilizer Demand of China Using the LePA Model.docx by Wenjia Yu (9422059)

“…It is necessary to avoid excess P input in agriculture through estimating P demand. We used the legacy P assessment model (LePA) to estimate P demand based on soil P management at the county, regional, and country scales according to six P application rate scenarios: (1) rate in 2012 maintained; (2) current rate maintained in low-P counties and P input stopped in high-P counties until critical Olsen-P level (CP) is reached, after which rate equals P-removal; (3) rate decreased to 1–1.5 kg ha⁻¹ year⁻¹ in low-P counties after CP is reached and in high-P counties; (4) rate in each county decreased to 1–8 kg ha⁻¹ year⁻¹ after soil Olsen-P reached CP in low P counties; (5) rate in each county was kept at P-removal rate after reduction; (6) P input was kept at the rate lower than P-offtake rate after reduction. …”

Table_2_Pregnancy Complications and Outcomes Among Women With Congenital Heart Disease in Beijing, China.docx by Yang Liu (4829)