IIS balances anti-proliferating (tumor-suppressive) and pro-proliferating (oncogenic) activities across tissue boundaries. by Wenjing Qi (142213)

“…Signaling activities of at least two tissues contribute to IIS homeostasis and may explain, why DAF-16 hyperactivity (in the hypodermis) may cause germline tumors in <i>daf-2(+)</i> background, whereas <i>daf-2(-)</i> (or starvation) decreases DAF-16 oncogenic potential, although in a simplistic view, it is thought to activate DAF-16.…”

Data_Sheet_1_Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy.pdf by Chang Xiaoyu (18426012)

“…Conversely, the BITC treatment group, when compared to the EP group, showed enhanced transcription levels of Nrf2, HO-1, and NQO1, along with increased GSH-Px activity, and a decrease in MDA content.…”

Histological findings of the tibial articular cartilage at a high magnification. by Ikufumi Takahashi (5146823)

Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication by Jinghua Yu (279880)

“…<p>Numerous viruses manipulate host factors for viral production. We demonstrated that human enterovirus A71 (EVA71), a primary causative agent for hand, foot, and mouth disease (HFMD), increased the level of the DNA damage response (DDR) marker γ-H2AX. …”

Possible Increase in Serum FABP4 Level Despite Adiposity Reduction by Canagliflozin, an SGLT2 Inhibitor by Masato Furuhashi (85555)

“…Here we investigated whether canagliflozin, an SGLT2 inhibitor, modulates serum FABP4 level.…”

Image 2_Neutrophil proteins as potential biomarkers for a sputum-based tuberculosis screening test.tif by Mark Chambers (1845670)

Table_1_Long-Term Inhibition of Notch in A-375 Melanoma Cells Enhances Tumor Growth Through the Enhancement of AXIN1, CSNK2A3, and CEBPA2 as Intermediate Genes in Wnt and Notch Pat... by Faezeh Keyghobadi (9044234)

“…In A375 with B-raf mutation, DAPT decreased the level of NOTCH1, NOTH2, and HES1 as downstream genes of the Notch pathway. …”

Effects of improved water, sanitation, and hygiene and improved complementary feeding on environmental enteric dysfunction in children in rural Zimbabwe: A cluster-randomized contr... by Ethan K. Gough (8452386)

“…We measured EED biomarkers that reflect all domains of the hypothesized pathological pathway. …”

Treatment with a TRPV agonist reduces the ability of mf to establish infection in mosquitoes. by Nicolas J. Wheeler (8947214)

“…<p>(A) NAM added to blood at up to 50 mM increases the proportion of blood-fed mosquitoes when allowed to feed to repletion but reduces mosquito blood feeding at concentrations greater than 50 mM. …”

Low blue carbon storage in eelgrass (<i>Zostera marina</i>) meadows on the Pacific Coast of Canada by Victoria R. Postlethwaite (5391026)

“…Sediment carbon concentrations did not exceed 1.30%C_org, and carbon accumulation rates ranged from 2.90–39.61 g C_org m^-2 yr^-1, decreasing with depth and averaging 10.8 ± 5.2 g C_org m^-2 yr^-1. …”

Antitumor activities of a novel fluorinated small molecule (A1) in CT26 colorectal cancer cells: molecular docking and in vitro studies by Hossein Khorramdelazad (15317069)

“…Moreover, treatment with 60 μg/mL of <b>A1</b> and 100 ng/mL of CXCL12 for 72 h significantly decreased the number of cells expressing the CXCR4 receptor compared to the control group treated with CXCL12. …”

Image_1_Human Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Atopic Dermatitis by Regulating the Expression of MIP-2, miR-122a-SOCS1 Axis, and Th1/Th2 Responses.jpeg by Misun Kim (3089739)

“…The AdMSCs attenuated clinical symptoms associated with AD, decreased numbers of degranulated mast cells (MCs), IgE level, amount of histamine released, and prostaglandin E2 level. …”

Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor by Wenjuan Wang (31234)

“…Histopathological change, cell apoptosis and infarct area were respectively determined by hematoxylin–eosin staining, terminal deoxynucleotidyl transfer-mediated dUTP nick end labeling (TUNEL) analysis and 2,3,5-triphenyltetrazolium chloride staining. Tissue angiotensin II (Ang II) and ACE activity were detected by enzyme-linked immunosorbent assays. …”

STATc is a key regulator of the transcriptional response to hyperosmotic shock-0 by Jianbo Na (12352)

“…Cell volume was measured with a microcapillary. Values represent the mean of three independent experiments ± standard deviation (SD). …”

CSF N-Glycan Profiles to Investigate Biomarkers in Brain Developmental Disorders: Application to Leukodystrophies Related to eIF2B Mutations by Anne Fogli (138515)

“…In CSF, but not in plasma, of eIF2B-mutated patient samples, we found increased relative intensity of bi-antennary structures and decreased tri-antennary/bisecting structures in N-glycan profiles. …”

Tree cover limits occupancy of a declining game bird by Bradley Kubecka (7387181)

“…Only 2 of 144 sites were characterized by low-moderate canopy cover (<50%) with a moderate fire frequency (burned 5 and 7 times since 2010). …”

Table 1_Forewarned is forearmed: rice plants develop tolerance to post-anoxia during anoxic conditions by proteomic changes.xlsx by Anton E. Shikov (9433655)

“…</p>Methods<p>In this study, we analyzed the impact of anoxia and re-aeration on tolerant rice at a proteomic level using two-dimensional gel electrophoresis followed by mass spectrometry. …”

Data Sheet 1_Forewarned is forearmed: rice plants develop tolerance to post-anoxia during anoxic conditions by proteomic changes.pdf by Anton E. Shikov (9433655)

“…</p>Methods<p>In this study, we analyzed the impact of anoxia and re-aeration on tolerant rice at a proteomic level using two-dimensional gel electrophoresis followed by mass spectrometry. …”

Prevention of Premature Ovulation by Administration of Gonadotropin Releasing Hormone Antagonist the day After Ovulation Triggering in Diminished Ovarian Reserve Patients by Bulat Aytek Sik (12973066)

“…We randomized patients into two groups. The case group comprised patients who had single-dose GnRH antagonist injection the day after hCG triggering formed, and the patients who had the standard treatment regime formed the control group. …”

Altered mRNA Editing and Expression of Ionotropic Glutamate Receptors after Kainic Acid Exposure in Cyclooxygenase-2 Deficient Mice by Luca Caracciolo (221279)

“…Furthermore, we analyzed RNA editing levels and found that the level of GluR3 R/G editing site was selectively increased in the hippocampus and decreased in the cortex in COX-2^−/− compared with WT mice. …”