Prospective and longitudinal natural history study of patients with Type 2 and 3 spinal muscular atrophy: Baseline data NatHis-SMA study by Aurélie Chabanon (5562944)

“…As an approved treatment becomes available, untreated patients will soon become rare, further intensifying the need for a rapid, prospective and longitudinal study of the natural history of SMA Type 2 and 3. Here we present the baseline assessments of 81 patients aged 2 to 30 years of which 19 are non-sitter SMA Type 2, 34 are sitter SMA Type 2, 9 non-ambulant SMA Type 3 and 19 ambulant SMA Type 3. …”

Decrease in number of activated macrophages in demyelinated nerves subjected to 1hr ES. by Nikki A. McLean (643606)

“…Note: ES results in a significant decrease in the ED-1 IF 10d post-LPC (5d post-ES; K) and 12d post-LPC (7d post-ES; N) relative to LPC only in a pattern suggestive of movement toward lateral edges and egress (arrow). …”

Kato-Katz storing experiment: Absolute median fecal egg counts (FEC) change over time for (A) hookworm (n = 67 for room temperature, n = 62 for refrigerator), (B) <i>A</i>. <i>lumb... by Felix Bosch (10024550)

Generated dynamics for the fourth simulation ‘Cooling of HVC’: We simulated two cooling experiments, where the format is the same as in <b>Figure 5</b> with arbitrary units. by Izzet B. Yildiz (191749)

Quantitative imaging and analysis reveals that slow migrating cells increase in area while fast migrating cells decrease in area. by Jacob M. Kowalewski (780662)

“…(D) Scatter Plot: The net value of protrusion minus retraction areas (delta (Δ) Cell Area, μm²) is shown as a function of Cell Speed. …”

Loss of Slfn3 induces a gender-dependent repair vulnerability after 50% bowel resection by Emilie DeKrey (9389738)

“…</a>Differentiation markers sucrase isomaltase, Dpp4, Glut2, and SGLT1 were all decreased. This suggests that enterocytic differentiation effort is incompatible with a rapid proliferation shift in intestinal adaptation. …”

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes by David A. Griffith (1348392)

Adjustment for the individual conus medullaris (CM) length (60, 50, 40, and 30 mm for the displayed cases). by Silvan Büeler (18389510)

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand by David Hauton (341981)

“…Hearts of male offspring subjected to Maternal Hypoxia showed a 20% decrease in cardiac output (<i>P</i><0.05), despite recording a 2-fold increase in glucose oxidation (<i>P</i><0.01) and 2.5-fold increase (<i>P</i><0.01) in palmitate oxidation. …”

A-p50 affects A549 cell survival through inhibition of NF-κB-mediated transcriptional activation by Jing Mi (18654)

“…Ad-A-p50 virus-injected tumor tissues show a decrease in Ki67 protein expression compared with Ad-siNT-injected tumor tissues (×100 magnification, brownish red nuclear stain), consistent with a decrease in cell proliferation. …”

Decreased CCL2 levels protect A20^AEC-KO mice against influenza A infection by Jonathan Maelfait (181048)

Reduced skin lipid content in obese Japanese women mediated by decreased expression of rate-limiting lipogenic enzymes by Yoshiko Horie (4923043)

“…Both skin cholesterol and fatty acid levels exhibited an “inverted-U” relationship with BMI, suggesting that there is an optimal BMI for peak lipid content and barrier function. Decreased lipid levels at higher BMI were accompanied by downregulated expression of <i>PPARδ</i> and other genes related to lipid metabolism, including those encoding acetyl-CoA carboxylase and HMG-CoA reductase, the rate-limiting enzymes for fatty acid and cholesterol synthesis, respectively. …”

The ketogenic diet causes a significant decrease in insulin, but does not affect the PI3K pathway. by Mai T. Dang (772520)

Most acute brain lesions in the white matter (Aa, Ba) showed a decrease in size and/or faded. by Su-Hyun Kim (573826)

Demographic characteristics of 50 DENV-2 viremic feedings evaluated for infectiousness to <i>Aedes aegypti</i> mosquitoes. by Louis Lambrechts (241741)

DataSheet1.docx by Rui Hong Guo (4963240)

“…Interestingly, host contact increased the expression and secretion of V. vulnificus RtxA1 toxin, which was decreased and delayed by the rpoS mutation. …”

Analysing system robustness if the diffusion rate of the activator and inhibitor species is allowed to decrease as the concentration of PLK4 increases. by Zachary M. Wilmott (17419831)

“…Also, when these concentrations of PLK4 are increased further, they do not readily generate more than 2 to 3 PLK4 peaks. <b>(B)</b> The phase diagram shown here is the same as that shown in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002391#pbio.3002391.g003" target="_blank">Fig 3C</a>, where we adapted Model 1 to allow the diffusivity of the PLK4 species to decrease as the concentration of PLK4 increases. …”

Large amounts of ingested phenylpyruvate are required to decrease the survival of adult <i>A. gambiae</i> mosquitoes. by Silke Fuchs (506300)

Chronic Arachidonic Acid Administration Decreases Docosahexaenoic Acid- and Eicosapentaenoic Acid-Derived Metabolites in Kidneys of Aged Rats by Masanori Katakura (816112)

“…Levels of docosahexaenoic acid-derived protectin D1, eicosapentaenoic acid-derived 5-, and 18-hydroxyeicosapentaenoic acids, and resolvin E2 and E3 decreased in the ARA-administered group. …”

<i>Otx</i> knockdown causes a decrease in <i>dct</i> expression in the developing RPE. by Brandon M. Lane (123574)

“…<i>dct</i> expression was reduced only in the ventral most region of the optic cup in single morphants (B–D, white arrows) compared to controls (A). <i>dct</i> expression was significantly decreased in the ventral RPE of <i>otx1a</i>/<i>otx2</i> morphants and to an even greater degree in <i>otx1a</i>/<i>otx1b</i>/<i>otx2</i> morphants (E–F, white arrows). …”