Table 4_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

-866G/A and Ins/Del polymorphisms in the UCP2 gene and diabetic kidney disease: case-control study and meta-analysis by Cristine Dieter (6830255)

“…<div><p>Abstract Uncoupling protein 2 (UCP2) decreases reactive oxygen species (ROS). …”

Table_1_Sphingolipids as a Culprit of Mitochondrial Dysfunction in Insulin Resistance and Type 2 Diabetes.docx by Kamila Roszczyc-Owsiejczuk (10322705)

“…Adverse effects of sphingolipid accumulation have recently been linked to the activation of protein kinase Cζ (PKCζ) and protein phosphatase 2A (PP2A), which, in turn, negatively affect phosphorylation of serine/threonine kinase Akt [also known as protein kinase B (PKB)], leading to decreased glucose uptake in skeletal muscles as well as increased gluconeogenesis and glycogenolysis in the liver. …”

The role of pioglitazone in antioxidant, anti-inflammatory, and insulin sensitivity in a high fat-carbohydrate diet-induced rat model of insulin resistance by H.M. Al-Muzafar (12728233)

“…<div><p>We explored the cascade effects of a high fat-carbohydrate diet (HFCD) and pioglitazone (an anti-diabetic therapy used to treat type 2 diabetes mellitus (T2DM)) on lipid profiles, oxidative stress/antioxidant, insulin, and inflammatory biomarkers in a rat model of insulin resistance. …”

Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…We studied the impact of 1, 3, or 6 months of canagliflozin (CANA), an SGLT2i treatment, on the skeleton of 6-month-old genetically heterogeneous UM-HET3 mice. …”

Image_2_Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis.tiff by Issa Beegun (11358306)

Image_2_Klebsiella pneumoniae ST258 Negatively Regulates the Oxidative Burst in Human Neutrophils.tif by Luis A. Castillo (6638081)

Data_Sheet_2_Microbial ecosystem responses to alkalinity enhancement in the North Atlantic Subtropical Gyre.CSV by Adam V. Subhas (13146195)

“…We conducted 4-day microcosm incubation experiments at sea, spiked with three increasing amounts of alkaline sodium salts and a ¹³C-bicarbonate tracer at constant pCO₂. …”

Table_2_Knockdown of NDUFC1 inhibits cell proliferation, migration, and invasion of hepatocellular carcinoma.xlsx by Fang Han (435237)

“…According to the detection of complex1 activity, we found that the activity of NDUFC1 silenced group decreased, whereas the content of ROS increased. …”

Data_Sheet_2_v1_Significance of Pseudomeningocele After Decompressive Surgery for Chiari I Malformation.pdf by Artur Balasa (12564976)

Data_Sheet_2_v1_Significance of Pseudomeningocele After Decompressive Surgery for Chiari I Malformation.pdf by Artur Balasa (12564976)

Table_2_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX by Enas Al-khlifeh (17286364)

“…Phylogenetic analysis supported the morphological identification of the rodents and revealed a marked genetic difference between the two heterospecific species. We found that bioclimatic zone had a significant effect on the gut microbiota composition while host phylogeny did not. …”

DataSheet_2_Statin Treatment as a Targeted Therapy for APC-Mutated Colorectal Cancer.pdf by Hannah Shailes (12698270)

Table3_UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival.XLSX by Ruth Nousiainen (11004780)

“…The silencing of UBE2C in two HB cell models resulted in decreased cell viability. …”

Image_2_Genetic and Molecular Evaluation of SQSTM1/p62 on the Neuropathologies of Alzheimer’s Disease.TIFF by Wei Dong (6479)

Table1_UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival.XLSX by Ruth Nousiainen (11004780)

“…The silencing of UBE2C in two HB cell models resulted in decreased cell viability. …”

Video_2_Force and Stepwise Movements of Gliding Motility in Human Pathogenic Bacterium Mycoplasma pneumoniae.AVI by Masaki Mizutani (11476414)

“…We detected stepwise movements, likely caused by a single leg under 0.2-0.3 mM free sialylated oligosaccharides. …”

Table_2_Genetic and Molecular Evaluation of SQSTM1/p62 on the Neuropathologies of Alzheimer’s Disease.DOCX by Wei Dong (6479)