Association and dissociation of BODIPY FL GTPγS with PfG from <i>Plasmodium</i>. by Annette Kaiser (386455)

“…<p>Part A Absolute Fluorescense of binding of 50 nmol BODIPY FL GTPγS to the plasmodial, PfG-protein (black line). …”

DataSheet_1_Integrative analysis of mitochondrial metabolic reprogramming in early-stage colon and liver cancer.pdf by Yeongmin Kim (4438870)

“…Using a genome-scale metabolic model, we demonstrated that HMGCS2 suppression increased glycolysis, lipid biosynthesis, and elongation while decreasing fatty acid oxidation in colon cancer cells. …”

Reported Figure Data. by Rhea Sullivan (18824253)

“…To optimize our model, we identified that a longer neural induction and regional patterning period increases expression of canonical opioid receptors mu and kappa in midbrain neural progenitors compared to a shorter protocol (<i>OPRM1</i>, two-tailed t-test, <i>p</i> =  0.004; <i>OPRK1</i>, <i>p</i> =  0.0003). …”

A stochastic model for microtubule-dependent movements of human adenovirus. by Mattia Gazzola (255327)

“…Equations <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Greber1" target="_blank">[1]</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Gross1" target="_blank">[6]</a> describe the dynamics of the model: <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Schliwa1" target="_blank">[3]</a>/<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Vale1" target="_blank">[4]</a> dynein binding/unbinding and decrease/increase of the number (ρ) of the available motor binding sites on the virus capsid with d_α/d_δ binding/unbinding rates, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Welte1" target="_blank">[5]</a>/<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Gross1" target="_blank">[6]</a> kinesin binding/unbinding and decrease/increase of the number(ρ) of the available motor binding sites on the virus capsid with k_α/k_δ binding/unbinding rates, and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Greber1" target="_blank">[1]</a>/<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000623#pcbi.1000623-Brandenburg1" target="_blank">[2]</a> dynein/kinesin motor stepping with d_μ/k_μ stepping rates. …”

Equine-IL10 Western blot. by Elizabeth Crabtree (5685311)

MOR activation inhibits glutamate release onto a subset of LHb neurons. by Elyssa B. Margolis (148265)

“…Scale bars 40 pA and 50 ms. The cumulative probability plots for this same neuron (D) show a shift to larger inter-event intervals (<i>i</i>) indicating a decrease in event frequency, but no change in event amplitude (<i>ii</i>), during DAMGO application. …”

Activity of the P_<i>comK</i> promoter in Rho⁺ cells. by Vladimir Bidnenko (4258573)

Table2_Targeted metabolomics analysis of nucleosides and the identification of biomarkers for colorectal adenomas and colorectal cancer.XLSX by Weifang Zheng (10228013)

“…The results showed that the concentrations of N⁶-methyladenosine (m⁶A), N¹-methyladenosine (m¹A), and 3-methyluridine (m³U) were increased in patients with CRC, whereas the concentrations of N²-methylguanosine (m²G), 2′-O-methyluridine (U_m), and 2′-O-methylguanosine (G_m) were decreased in patients with CRC, compared with the healthy controls and patients with colorectal adenomas. …”

Data_Sheet_2_Episodic Memory Impairment Mediates the Loss of Awareness in Mild Cognitive Impairment.CSV by Geoffroy Gagliardi (6280820)

Presentation_1_Human Beta Defensin 2 Ameliorated Alcohol-Associated Liver Disease in Mice.PPTX by Jeffrey B. Warner (5793881)

“…The gut-liver axis is a critical factor contributing to susceptibility to liver injury due to alcohol consumption. In the current study, we tested whether human beta defensin-2 (hBD-2), a small anti-microbial peptide, attenuates experimental chronic ALD. …”

Image_2_Safranal Alleviated OVA-Induced Asthma Model and Inhibits Mast Cell Activation.jpg by Peeraphong Lertnimitphun (8318799)

“…</p>Results<p>Safranal reduced the level of serum IgE, the number of mast cells in lung tissue were decreased and Th1/Th2 cytokine levels were normalized in OVA-induced asthma model. …”

Data_Sheet_2_Voluntary Saccade Training Protocol in Persons With Parkinson’s Disease and Healthy Adults.pdf by Paul B. Camacho (6557636)

“…</p><p>Objective: We report an experimental protocol that tests a training paradigm following the principle of specificity to improve voluntary saccade velocity and amplitude, while decreasing latency and the number of compensatory saccades.…”

Image2_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.tiff by Jiao Wang (47178)

“…The incidence rates of diarrhea (risk ratio = 0.21, 95% CI [0.06, 0.81], p = 0.02) were higher in the CHM formulas group than in the control group, whereas other adverse events were not significantly different between the two groups (p > 0.05). We evaluated the PASI score of mice on day 7 and found that SHI and DMA also alleviated psoriatic lesions (MD = -3.36, 95% CI [-4.67, -2.05], p < 0.00001, I² = 94%). …”

Image2_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.tiff by Jiao Wang (47178)

“…The incidence rates of diarrhea (risk ratio = 0.21, 95% CI [0.06, 0.81], p = 0.02) were higher in the CHM formulas group than in the control group, whereas other adverse events were not significantly different between the two groups (p > 0.05). We evaluated the PASI score of mice on day 7 and found that SHI and DMA also alleviated psoriatic lesions (MD = -3.36, 95% CI [-4.67, -2.05], p < 0.00001, I² = 94%). …”

Table2_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…The incidence rates of diarrhea (risk ratio = 0.21, 95% CI [0.06, 0.81], p = 0.02) were higher in the CHM formulas group than in the control group, whereas other adverse events were not significantly different between the two groups (p > 0.05). We evaluated the PASI score of mice on day 7 and found that SHI and DMA also alleviated psoriatic lesions (MD = -3.36, 95% CI [-4.67, -2.05], p < 0.00001, I² = 94%). …”

Table2_Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis.docx by Jiao Wang (47178)

“…The incidence rates of diarrhea (risk ratio = 0.21, 95% CI [0.06, 0.81], p = 0.02) were higher in the CHM formulas group than in the control group, whereas other adverse events were not significantly different between the two groups (p > 0.05). We evaluated the PASI score of mice on day 7 and found that SHI and DMA also alleviated psoriatic lesions (MD = -3.36, 95% CI [-4.67, -2.05], p < 0.00001, I² = 94%). …”

Data_Sheet_2_Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster.pdf by Stephen M. Shuster (629138)

“…We found that: (1) the average fitnesses of males and females within each population were identical when adjusted by the sex ratio; (2) the variance in fitness in male and female prairie voles was comparable to that of highly polygynous species; (3) The average fitnesses of male tactics, and of female tactics, were equivalent within and among years within each location; (4) consistent with negative frequency-dependent selection acting on mating phenotypes, the between-tactic variance in fitness for male and female mating tactics decreased with increasing study duration; (5) consistent with negative assortative mating, resident males, and wanderer females produced offspring primarily in monogamous partnerships, whereas wanderer males and resident females produced offspring primarily in polygamous partnerships. …”

MicroRNA 26a targets Ezh2 to regulate apoptosis in mouse ovarian granulosa cells by Shiwei Huo (10902387)

“…Dual-luciferase reporter assays confirmed Ezh2 as a miR-26a target. Exogenous expression in GCs of miR-26a mimics resulted in decreased Ezh2 expression, while miR-26a inhibition in GCs induced the opposite phenotype. …”

Table_2_Landscape Topography and Regional Drought Alters Dust Microbiomes in the Sierra Nevada of California.docx by Mia R. Maltz (4446295)

“…We sampled throughout two dry seasons and found that dust microbiomes differed by elevation across two summer dry seasons (2014 and 2015), which corresponded to competing droughts in dust source areas. …”

Image_2_Serum pro-inflammatory biomarkers associated with improvement in quality of life in pulmonary tuberculosis.tiff by Laura E. Carreto-Binaghi (16961523)

“…Although respiratory function tests objectively reflect lung disturbances in a specific moment, predictors of illness severity at the time of diagnosis are still lacking.</p>Methods<p>We measured serum pro-inflammatory cytokines (TNF-α and IL-8), eicosanoids (PGE2, LTB4, RvD1, Mar1, and LXA4), a marker of tissue damage (cell-free nucleosomes), and indicators of redox status (malonaldehyde, 8-isoprostane, total oxidants, and antioxidants), as well as a score of radiological abnormalities (SRA) and a QoL questionnaire, in 25 patients with pulmonary TB at the time of diagnosis (t0) and two months after the initiation of treatment (t2).…”