Table_1_Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2.docx by Hao Yang (328526)

“…</p>Results<p>Through a series of algorithmic filters, we identified PAK2 as a key gene promoting pancreatic cancer liver metastasis. …”

Image_1_Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2.tif by Hao Yang (328526)

“…</p>Results<p>Through a series of algorithmic filters, we identified PAK2 as a key gene promoting pancreatic cancer liver metastasis. …”

Atomoxetine Effects on Executive Function as Measured by the BRIEF-A in Young Adults with ADHD: A Randomized, Double-Blind, Placebo-Controlled Study by Lenard A. Adler (620169)

“…At endpoint, statistically significantly greater mean reductions were seen in the atomoxetine versus placebo group for the BRIEF-A Global Executive Composite (GEC), Behavioral Regulation Index (BRI), and Metacognitive Index (MI) scores, as well as the Inhibit, Self-Monitor, Working Memory, Plan/Organize and Task Monitor subscale scores (<i>p</i><.05), with decreases in scores signifying improvements in executive functioning. …”

Image_2_Vaginal Microbiota and Cytokine Levels Predict Preterm Delivery in Asian Women.tiff by Manoj Kumar (205700)

“…Using 16S ribosomal RNA gene sequencing we identified a predictive vaginal microbiota signature for PTB that was detectable as early as the first trimester of pregnancy, characterized by higher levels of Prevotella buccalis, and lower levels of Lactobacillus crispatus and Finegoldia, accompanied by decreased levels of cytokines including IFNγ, IL-4, and TNFα. …”

Image2_Butyrate suppresses experimental necrotizing enterocolitis–induced brain injury in mice.tif by Maribel Martinez (485567)

“…Background<p>Necrotizing enterocolitis (NEC) is a devastating disease in premature infants, and 50% of infants with surgical NEC develop neurodevelopmental defects. …”

Table2_Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia.DOCX by Song Yu (3073554)

“…<p>Introduction: High-altitude polycythemia (HAPC) is a common chronic high-altitude disease characterized by significantly increased erythrocyte, hemoglobin (Hb), and hematocrit values and decreased arterial oxygen saturation. …”

MST1/2 in PDGFR-α+ Cells negative feedback regulates TGF-β-induced Myofibroblasts Accumulation in Renal Fibrosis-Supplemental figures by Shuaiyu Wang (11511334)

“…Furthermore, we demonstrated that Hippo–MST as a negative feedback signal can decrease the renal fibrosis process by regulating the interaction between YAP and Smad2/3 in fibroblast. …”

Supplementary Material for: Dickkopf-Related Protein 2 is Epigenetically Inactivated and Suppresses Colorectal Cancer Growth and Tumor Metastasis by Antagonizing Wnt/β-Catenin Sign... by Wang C. (2954256)

“…<i>Results:</i> We show here that downregulation or silencing of <i>DKK2</i> was closely associated with the hypermethylation status of its promoter and that <i>DKK2</i> expression could be restored by demethylation treatment. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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Table_2_The effects of antioxidants on knee osteoarthritis: A systematic review and meta-analysis.docx by Mohammad Nejadhosseinian (14276618)

Image_2_Evolution of the S-Genomes in Triticum-Aegilops Alliance: Evidences From Chromosome Analysis.TIF by Alevtina S. Ruban (6039062)

“…To correlate the C-banding and FISH patterns we used the microsatellites (CTT)₁₀ and (GTT)₉, which are major components of the C-banding positive heterochromatin in wheat. …”

Table_2_Evolution of the S-Genomes in Triticum-Aegilops Alliance: Evidences From Chromosome Analysis.docx by Alevtina S. Ruban (6039062)

“…To correlate the C-banding and FISH patterns we used the microsatellites (CTT)₁₀ and (GTT)₉, which are major components of the C-banding positive heterochromatin in wheat. …”

Data_Sheet_1_Elevated CO2 Enhances Dynamic Photosynthesis in Rice and Wheat.docx by Huixing Kang (11510365)

“…We grew an Oryza sativa japonica cultivar and a Triticum aestivum cultivar under 400 μmol CO₂ mol⁻¹ air (ambient, A) and 600 μmol CO₂ mol⁻¹ air (elevated, E). …”

DataSheet_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx by Tom Houben (3185082)

“…<p>Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation. In this context, two-hydroxypropyl-β-cyclodextrin (CD) is increasingly considered as a novel pharmacological compound to decrease cellular cholesterol levels due to its ability to increase cholesterol solubility. …”

Table 1_Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice.xlsx by Xiaohang Wang (4862665)

“…After the cognition assessment, the mice were euthanized, and the inflammatory factors associated to the VaD were detected by immunofluorescence. We showed that the fluorescence intensities of IL-1β, IL-6, TNF-α, and TGF-β1 in hippocampus were decreased after the Pdpn knocking down in astrocytes of T2DM mice.…”

Doxorubicin efficacy as a function of intracellular pH. by Pawel Swietach (168173)

“…<p>Cell proliferation was measured using the CellTiter blue assay kit (quantified as a ratio of absorbance at 562 nm and 595 nm). Doxorubicin efficacy was determined from dose-response curves as the concentration which results in a 50% decrease in proliferation (EC₅₀). …”

Bioreductively Activatable Prodrug Conjugates of Combretastatin A‑1 and Combretastatin A‑4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia by Blake A. Winn (8604801)

“…The related CA1-<i>gem</i>-dimethylnitrothiophene BAPC <b>41</b> was also promising (HCR = 12.5) with complete cleavage (90 min) upon treatment with POR. In a preliminary in vivo dynamic bioluminescence imaging study, BAPC <b>45</b> (180 mg/kg, ip) induced a decrease (within 4 h) in light emission in a 4T1 syngeneic mouse breast tumor model, implying activation and vascular disruption.…”

Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter by Laura László (3221631)

“…Here we present a structural model of the ABCG2 homodimer based on this fold and detail the experimental results supporting this model. …”

Table_2_Asynchronous Accumulation of Organic Carbon and Nitrogen in the Atlantic Gateway to the Arctic Ocean.docx by Maria L. Paulsen (5600657)

“…While particulate organic carbon (POC), particulate organic nitrogen (PON), and dissolved organic carbon (DOC) accumulated in the surface waters from January to May, the dissolved organic nitrogen (DON)-pool decreased substantially (Δ – 50 μg N L^-1). …”

Image_2_Asynchronous Accumulation of Organic Carbon and Nitrogen in the Atlantic Gateway to the Arctic Ocean.TIFF by Maria L. Paulsen (5600657)

“…While particulate organic carbon (POC), particulate organic nitrogen (PON), and dissolved organic carbon (DOC) accumulated in the surface waters from January to May, the dissolved organic nitrogen (DON)-pool decreased substantially (Δ – 50 μg N L^-1). …”