Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

A Yoga Strengthening Program Designed to Minimize the Knee Adduction Moment for Women with Knee Osteoarthritis: A Proof-Of-Principle Cohort Study by Elora C. Brenneman (795723)

“…A secondary objective was to determine whether the program could improve mobility and fitness, and decrease peak KAM during gait. …”

Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy by Yong-Chul Kim (1637572)

“…We randomly assigned patients either to receive tacrolimus or placebo with stratification by using a renin angiotensin system blocker. …”

Reduced follicles, decreased ovulation and decreased fertilization of female Meox-2-cre/Separase S1121A mutant mice. by Juan Xu (225010)

Controlling the Temperature and Speed of the Phase Transition of VO₂ Microcrystals by Joonseok Yoon (1419355)

Subjects:

Non-Pneumatic Anti-Shock Garment (NASG), a First-Aid Device to Decrease Maternal Mortality from Obstetric Hemorrhage: A Cluster Randomized Trial by Suellen Miller (294598)

“…We hypothesized the NASG group would have a 50% reduction in adverse outcomes.…”

Here we speculate on the possible interactions between cell autonomous circadian and somite oscillator components during somite formation and differentiation. by Kristen L. Curran (95520)

Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

Subjects:

Unique Biofilm Signature, Drug Susceptibility and Decreased Virulence in <em>Drosophila</em> through the <em>Pseudomonas aeruginosa</em> Two-Component System PprAB by Sophie de Bentzmann (116508)

“…<em>Pseudomonas aeruginosa</em>, a Gram-negative bacterium causing severe infections in humans, forms biofilms and is a fantastic example for fine-tuning of the transition between planktonic and community lifestyles through two-component systems (TCS). Here we decipher the regulon of the <em>P. aeruginosa</em> response regulator PprB of the TCS PprAB. …”

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... by Shuhei Ikeda (2380180)

Subjects:

DMB treatment decreased neuronal apoptosis in cerebral ischemia. by Huinan Zhang (849524)

Screening Sheet: A sheet that contains the full screening process that we used to include or exclude any study. by Mohamed R. Abdelraouf (21501468)

Fixation becomes unlikely with decreasing fitness of mutant homozygotes, variance in allele frequency increases with migration rate. by Philipp M. Altrock (340203)

Image_1_Relative Diazotroph Abundance in Symbiotic Red Sea Corals Decreases With Water Depth.tif by Arjen Tilstra (6915227)

“…Consequently, coral-associated diazotroph communities may exhibit distinct activity patterns across a water depth gradient. We thus compared relative abundances of diazotrophs in the tissues of two common hard coral species, Podabacia sp. and Pachyserisspeciosa, along their water depth distribution (10–30 m and 30–50 m, respectively) in the Central Red Sea. …”

Increased GLB1 correlates with decreased proliferation and increased expression of HP1γ in benign tissue. by Jennifer Wagner (523883)

“…<p>The microarrays were immunostained for the proliferation protein Ki67, the heterochromatin protein HP1γ increased in senescence, and p27, a marker decreased in terminal senescence. Separating benign cores into high and low Ki67 and GLB1 staining, we found that the population of high GLB1-low Ki67 (box 4), representing the senescent population, expressed low p27 and high HP1γ as expected for senescent cells. …”