Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

Carbohydrate metabolism during <i>Listeria monocytogenes</i> infection. by Adam Bajgar (730380)

In both figures, the mean reaction times to select an adult or an infant target are shown for both administration conditions (oxytocin or placebo) (± SEM). by Sarah K. C. Holtfrerich (3353693)

Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. by Takuro Iwao (14636741)

Carbohydrate metabolism during <i>Streptococcus pneumoniae</i> infection of flies with manipulated adenosine levels. by Adam Bajgar (730380)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Adult hemocytes quantification and phagocytosis capability. by Adam Bajgar (730380)

Host survival and pathogen loads during <i>Streptococcus pneumoniae</i> infection of flies with manipulated adenosine levels. by Adam Bajgar (730380)

DHA does not affect the expression of IFNγR1 & R2 but decreases STAT1 phosphorylation in non-infected J774A.1 cells primed with IFNγ. by Diana L. Bonilla (248104)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

Systemic metabolic switch and glycogen breakdown are required for effective resistance to <i>Streptococcus pneumoniae</i>. by Adam Bajgar (730380)

Host survival and pathogen load during <i>Listeria monocytogenes</i> infection. by Adam Bajgar (730380)

Image_2_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Influence of stabilized MetA protein on the <i>E.coli</i> WE strain growth under stressful conditions. by Elena A. Mordukhova (646403)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

“…JQ1 (50–400 nM) increases insulin secretion from INS-1 cells in a concentration dependent manner. …”

Linear decrease of delta power (1.1–5.0 Hz) across the first three sleep cycles in the cortical, hippocampal and scalp recordings. by Fabio Moroni (34208)

Old rat serum present higher levels of pro-inflammatory cytokine. by María Paz Saldías (4430032)

Mean (±95%CI) 24-hr post soreness measured using a numeric pain rating scale (1–10) for the Nordic hamstring exercise, Sprint, and control groups. by Nicholas J. Ripley (14709756)

Decrease in the mean age at onset of T2DM across different BMI categories in hypertensive and non-hypertensive patients. by Arshad Mohamed Channanath (553879)