Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7. by Taulant Bacaj (803415)

“…Recordings were performed in the presence of 1 μM tetrodotoxin, 20 μM CNQX, and 50 μM AP5 to isolate inhibitory currents. <b>B.</b> Simultaneous ablation of Syt1 and Syt7 decreases the RRP size of inhibitory synapses in a manner that is rescued by WT Syt7 (Syt1^WT) but not Syt7 with mutations in the top C2 domain sequences containing the Syt7 Ca²⁺ binding sites (Syt7^C2A*^B*). …”

NEMO knockout murine dermal fibroblasts show a decreased nuclear translocation of p65. by Patrick Meyer (3395285)

Oral UOX decreased SUA (A), BUN (B) and Cr (C) (mean ± SD, n = 10). by Yu Yun (4710340)

Rab7A decreases BST2 cell surface expression and is required for Vpu-induced BST2 cell surface downregulation. by Marina Caillet (198168)

“…<p>(<b>A</b>–<b>B</b>) Rab7A decreases BST2 cell surface expression. …”

Hepatic B1 cells increase whereas PC B1 cells decrease after <i>S</i>. <i>japonicum</i> infection. by Liang Yong (6836771)

Decreases in locomotor responses to a single METH injection in <i>Ptprz</i>-KO mice. by Akihiro Fujikawa (122649)

DOX decreases body mass gain over time in a sub-chronic toxicity model. by Gonçalo C. Pereira (156673)

(A) The temperature sensitive allele of <i>HEM1</i> leads to a significant decrease in the endogenous levels of Cia2 and Mms19. by Ifat Lev (469072)

Wnt5a expressing tumors demonstrate a decrease in markers of the basal tumor subtype. by Stephanie L. Easter (662168)

“…MMTV-Wnt1;MMTV-Wnt5a tumors demonstrated a significant decrease in K6-expressing cells as measured by T-test (* = p<0.05).…”

Mitochondrial dysfunction is driven by decreased mitochondrial dynamics. by Piero Dalle Pezze (622889)

“…<p>(A) Sensitivity analysis averaged along the time course for the mitochondrial species in the model by varying the mitochondrial-related kinetic rate constant parameters. …”

Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

Subjects:

Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation. by Arindam P. Ghosh (317870)

“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”

Mean ± SD values of unipedal stance parameters evaluated at the different time points of the postural training session. by Cristina Dolciotti (16317330)

OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

“…After 4 weeks, when the tumor size was approximately 100 mm³ (T₀) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”

The levels of soluble Rpb1 are decreased in <i>not5Δ</i>. by Zoltan Villanyi (650435)

The recruitment of MYD88 to TLR2 and IRAK-4 phosphorylation are decreased in β3-integrin–silenced cells. by Tatiana Gianni (499634)

Decreased FOXP3 Treg induction in LAG-3 KO T-cells in an <i>in vivo</i> self-tolerance. by Nicholas M. Durham (174371)

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)

Modifying pregnenolone to decrease its lipophilicity results in decreased cellular uptake. by Jeffrey M. McManus (7512926)

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The receptors were activated by EC₅₀ concentrations of glutamate with saturating concentration (100 μM) of glycine at holding potential of -40 mV. The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”