LC–MS/MS analysis of 5-, 8-, 11-, 12- and 15-HETE levels in WT and Tie2-CYP2J2 Tr mouse heart perfusates at baseline and post-ischemia. by Ahmad Hanif (3094800)

Subjects:

Mass Spectrometry Experiment 1: Comparison of Mito Matrix and Vpu WT and mutants. by Charlotte A. Stoneham (10819125)

Three Ca_V3.3 variants left-shift the window current, while the A398V completely abolishes the window current. by Yousra El Ghaleb (22075892)

Subjects:

Sensitizing the lungs with <i>Kdm5b</i>^f/f-CD11c-Cre⁺ DCs prior to infection results in decreased pathology following RSV challenge. by Catherine Ptaschinski (756139)

Impact of MK2-deficiency on adipose tissue inflammation. by Jan Freark de Boer (631340)

Subjects:

Stability parameters for SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

Kinetic parameters of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

M^pro confers a significant reduction in growth in yeast caused by decreases in a variety of cellular proteins. by Jin Ou (16914305)

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…^†These substitutions resulted in a k_d >4X that of WT-FVIII-C2 for BO2C11 or abrogated binding to BO2C11. …”

RNF5 loss decreases ERK and Akt activation, CDK1 and Smo expression and KSHV lytic replication in PEL cells. by Xiaojuan Li (351842)

Serotonin deficiency decreases calcium transporters expression in the mammary gland on d 10 of lactation. by Jimena Laporta (383836)

Lack of PD-L1 expression by host tissues increases numbers of activated donor T cells but decreases donor Tregs in spleen. by Mohammad S. Hossain (415643)

CXCL8 (2, 20, and 200 pg/ml) and CCL20 (5, 50, and 500 pg/ml) enhanced Ki-67 gene expression, but only 200 pg/ml of CXCL8 and 500 pg/ml of CCL20 enhanced early osteogenic marker ge... by Janak L. Pathak (759122)

AMPK phosphorylation and AC5 and AC6 gene expression in hearts from WT and AMPKα2-/- mice following TAC. by Anne Garnier (130125)

Subjects:

Decreased osteoclasts invasion into bony defects of <i>db-/db-</i> mice. by Christoph Wallner (699861)

“…<p>(A) TRAP stainings of <i>db</i>^-/<i>db</i>^- and WT mice 7dpO revealed that osteoclasts invasion is decreased in <i>db</i>^-/<i>db</i>^- mice (arrows indicate TRAP-positive pixels) which could be confirmed by quantification of TRAP-positive pixel in the defect area (B). …”

HSP90 inhibition by RGRN-305 and 17-AAG decreased proinflammatory protein secretion. by Hakim Ben Abdallah (14578241)

Three variants lower the rheobase and increase firing frequency of Ca_V3.3, while the A398V variant shows the opposite effect. by Yousra El Ghaleb (22075892)

Subjects:

Treatment with rVP1 decreases NF-κB activation that modulates CCL2 production. by Tai-An Chen (211390)

Allergic patient B cells exhibit increased ADAM10 and sCD23 but decreased ADAM17 and TNF. by Lauren Folgosa Cooley (733432)

Su(H) and RBPJ AOS variants decrease DNA binding. by Ellen K. Gagliani (11478756)