Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Hamad, Anas

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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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Silicon Enhances Morpho–Physio–Biochemical Responses in Arsenic Stressed Spinach (Spinacia oleracea L.) by Minimizing Its Uptake حسب Saleem, Muhammad Hamzah

"…Fifteen days old seedlings of S. oleracea were subjected to the different concentrations of As, i.e., 0 (no As), 50, and 100 µM in the soil which were also supplied with the different exogenous levels of Si, i.e., 0 (no Si), 1.5, and 3 mM. Results from the present study revealed that the As toxicity induced a substantial decreased in shoot length, root length, number of leaves, leaf area, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, chlorophyll-a, chlorophyll-b, total chlorophyll, carotenoid content, net photosynthesis, stomatal conductance, transpiration rate, soluble sugar, reducing sugar, non-reducing sugar contents, calcium (Ca2+), magnesium (Mg2+), iron (Fe2+), and phosphorus (P) contents in the roots and shoots of the plants. …"
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Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment. حسب Kashir, Junaid

"…Male recruitment criteria required a minimum sperm count of 5 × 10 spermatozoa/mL, while all female patients included in this study yielded at least five oocytes for treatment. …"
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Investigating algal CO2 capture through screening of Qatari desert microalgae & cyanobacteria strains حسب Al Muraikhi, Mariam

"…A number of different trends in CO2 tolerance could be identified from the results; a number of strains showed a clear inhibition of growth with CO2 concentrations of 5% and higher, whilst others showed increasing growth rates for increasing CO2 concentrations up to 30%. …"
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The Association between Zinc and Copper and Cardiometabolic Risk Factors in Adults حسب Al Kudsi, Dana Samir

"…High Zn/Cu ratio increased the prevalence of low HDL (4.508; p?0.001) and MetS (5.570; p?0.01). These findings suggest that high Cu levels are associated with a protective effect on DBP, HDL, and MetS and that high plasma Zn/Cu ratio is associated with the risk of low HDL and MetS. …"
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Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability حسب Abushanab, Abdelrahman

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Bryophyte cover and richness decline after 18 years of experimental warming in alpine Sweden. حسب Alatalo, Juha M

"…Experimental warming with open-top chambers (OTCs) was applied for 18 years to a mesic meadow and a dry heath alpine plant community. …"
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Climate, trends and variability of extreme winds along the southwest coast of India حسب Abdulla, Cheriyeri Poyil

"…The 99th percentile wind speeds during premonsoon, SW monsoon and postmonsoon are 8.8, 12.3 and 8.9 m·s−1, respectively. A significant decreasing trend is observed in the 99th percentile wind speeds during 1979–2021, ranging from 3 to 6 cm·s−1·year−1 off Kerala coast. …"
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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function حسب Da'as, Sahar I.

"…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation-contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l-type Ca2+ (Cav1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …"
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STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJ... حسب El Gamal, Heba

"…Normal rat kidney (NRK-52E) cells were exposed to high glucose (30 mM) or normal glucose (5 mM) media for 24 to 72 hours, and then assessed for changes in cell viability using MTT assay. …"
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Impact of COVID-19 lockdown on smoking (waterpipe and cigarette) and participants' BMI across various sociodemographic groups in Arab countries in the Mediterranean Region حسب Al Sabbah, Haleama

"…RESULTS: Overall, the prevalence rate of smoking decreased significantly during the lockdown from 29.8% to 23.5% (p<0.05). …"
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Utilization of Two Microalgae Species, Synechococcus sp. and Cheatoceros sp., for Aquatic Toxicity Assessments in the Qatari Marine Environmen حسب Bacha, Sarah

"…The lowest growth rates were observed at the lowest temperatures, while a decreased rate was also observed at the highest temperature. …"
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Hot and Hypoxic environments inhibit simulated soccer performance and exacerbate performance decrements when combined حسب Aldous, Jeffrey

"…Sprint distance covered was unchanged (p>0.05) in HOT and HYP and only decreased in HH (−8%) compared with CON. Body mass (−2%), temperatures (+2–5%), and TS (+18%) were altered in HOT. …"
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The Effect of Experimental Recuperative and Appetitive Post-lunch Nap Opportunities, With or Without Caffeine, on Mood and Reaction Time in Highly Trained Athletes حسب Romdhani, Mohamed

"…Purpose: To investigate the effects of placebo (PLA), 20 min nap opportunity (N20), 5mg·kg−1 of caffeine (CAF), and their combination (CAF+N20) on sleepiness, mood and reaction-time after partial sleep deprivation (PSD; 04h30 of time in bed; study 1) or after normal sleep night (NSN; 08h30 of time in bed; study 2). …"
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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. حسب Al-Jaber, Hend

"…These factors included 2.5nM tumor necrosis factor-alpha (TNFα), 20 ng/ml interleukin-6 (IL-6), 10 micromole 4-hydroxynonenal (4HNE), and high insulin (HI) at a concentration of 100nM. …"
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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane حسب Rizk, Nasser M

"…Sulforaphane (SFN) has been suggested as a new potential anti-diabetic compound acting by reducing blood glucose levels through mechanisms not fully understood (1). …"
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Molecular and Peritoneal Microvascular Changes Cause Peritoneal Membrane Dysfunction by Uremia-Related Mechanisms حسب Zakaria, El-Rasheid

"…A subset of uremic animals exhibited very high net ultrafiltration which seems to correlate with a phenotype of extensive angiogenesis and uremia-induced hypertension. …"
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Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 حسب Comfort, Haley

"…The estimated number of stillbirths occurring at 20 weeks' gestation or longer decreased from 5·08 million (95% UI 4·07–6·35) in 1990 to 3·04 million (2·61–3·62) in 2021, corresponding to a 39·8% (31·8–48·0) reduction, which lagged behind a global improvement in neonatal deaths of 45·6% (36·3–53·1) for the same period (down from 4·03 million [3·86–4·22] neonatal deaths in 1990). …"
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