Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin by Yan Wang (15435)

Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma by Scott M. Thompson (231230)

CTSS inhibition-induced early ROS contributes to mitochondria-dependent apoptotic signaling. by Chien-Chang Huang (747832)

“…<p>(A) Allopurinol treatment reduced 6r-induced caspase-9/-3 activation. …”

DataSheet1_Synthesis and biological evaluation of novel benzothiazole derivatives as potential anticancer and antiinflammatory agents.pdf by Xuemei Xu (181089)

“…The active compound 6-chloro-N-(4-nitrobenzyl) benzo[d] thiazol-2-amine (compound B7) was screened through a series of bioactivity assessments, which significantly inhibited the proliferation of A431, A549 and H1299 cancer cells, decreased the activity of IL-6 and TNF-α, and hindered cell migration. …”

Multivariate analyses from plasma metabolome profile of G1 versus G2, G2 versus G3, and G3 versus G4 patients. by Ana Sofía Herrera-Van Oostdam (11355996)

“…The color boxes indicate whether metabolite concentration was increased (red) or decreased (blue). Figures were produced in MetaboAnalyst software v 4.0 (<a href="https://www.metaboanalyst.ca/" target="_blank">https://www.metaboanalyst.ca/</a>).…”

Table1_Molecular mechanism of the treatment of lung adenocarcinoma by Hedyotis Diffusa: an integrative study with real-world clinical data and experimental validation.XLSX by Sheng Wang (339979)

“…The transcription and expression level of CTNNB1 gene in the drug intervention group were significantly decreased.</p>Conclusion<p>H. diffusa inhibits the proliferation and promotes apoptosis of LUAD A549 cells, which may be related to the fact that H. diffusa can regulate the expression of CTNNB1.…”

DataSheet2_Molecular mechanism of the treatment of lung adenocarcinoma by Hedyotis Diffusa: an integrative study with real-world clinical data and experimental validation.ZIP by Sheng Wang (339979)

“…The transcription and expression level of CTNNB1 gene in the drug intervention group were significantly decreased.</p>Conclusion<p>H. diffusa inhibits the proliferation and promotes apoptosis of LUAD A549 cells, which may be related to the fact that H. diffusa can regulate the expression of CTNNB1.…”

Presentation_1_Acute Increase in O-GlcNAc Improves Survival in Mice With LPS-Induced Systemic Inflammatory Response Syndrome.PPTX by Josiane Fernandes Silva (8334927)

“…<p>Sepsis is a systemic inflammatory response syndrome (SIRS) resulting from a severe infection that is characterized by immune dysregulation, cardiovascular derangements, and end-organ dysfunction. …”

DataSheet1_Molecular mechanism of the treatment of lung adenocarcinoma by Hedyotis Diffusa: an integrative study with real-world clinical data and experimental validation.ZIP by Sheng Wang (339979)

“…The transcription and expression level of CTNNB1 gene in the drug intervention group were significantly decreased.</p>Conclusion<p>H. diffusa inhibits the proliferation and promotes apoptosis of LUAD A549 cells, which may be related to the fact that H. diffusa can regulate the expression of CTNNB1.…”

Data_Sheet_7_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Data_Sheet_1_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

S1 File - by Jinyan Feng (13016481)

“…The mRNA expression level of ATP6V1E1 was decreased in osteosarcoma. Compared with hFOB1.19, western blotting revealed that the expression of FDX1 was significantly elevated in osteosarcoma cells. …”

Table_1_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.DOCX by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Data_Sheet_4_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Data_Sheet_3_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Data_Sheet_6_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Data_Sheet_2_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Data_Sheet_8_Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses.PDF by Lisa Pointner (11264244)

“…BPE-primed BMDCs efficiently stimulated T cell activation, which was repressed by the TLR4 antagonist or PMB, and the addition of nLPS to Bet v 1 did not reproduce the effect of BPE. In vivo, immunization with BPE induced a significant Th2 polarization, whereas administration of BPE pre-incubated with PMB showed a decreased tendency. …”

Coordination Chemistry and Insulin-Enhancing Behavior of Vanadium Complexes with Maltol C₆H₆O₃ Structural Isomers by Katayoun Saatchi (2100859)

“…The in vivo efficacy of these compounds to lower the blood glucose levels of STZ-diabetic rats was tested; all but VO(en(ama)₂) produced significant decreases in plasma glucose levels. The results were compared to those of the benchmark compound BMOV [VO(ma)₂, bis(maltolato)oxovanadium(IV)], a known insulin-enhancing agent.…”

Coordination Chemistry and Insulin-Enhancing Behavior of Vanadium Complexes with Maltol C₆H₆O₃ Structural Isomers by Katayoun Saatchi (2100859)

“…The in vivo efficacy of these compounds to lower the blood glucose levels of STZ-diabetic rats was tested; all but VO(en(ama)₂) produced significant decreases in plasma glucose levels. The results were compared to those of the benchmark compound BMOV [VO(ma)₂, bis(maltolato)oxovanadium(IV)], a known insulin-enhancing agent.…”