E2 induces increased chromosome conformation capture contact frequencies but decreased proximity between enhancers and promoters. by Luciana I. Gómez Acuña (18605719)

Differences in abundance of lipid molecules in liver of <i>Fmo5</i>^<i>-/-</i> and WT mice. by Ian R. Phillips (5074121)

“…<p>(A) Volcano plot representation of lipid molecules (log₂-fold change) of <i>Fmo5</i>^<i>-/-</i> vs WT mice. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Prdm5 loss results in decreased Collagen I and Decorin levels and leads to reduced bone formation <i>in vivo</i>. by Giorgio Giacomo Galli (165327)

The bioluminescent responses of the pILAnrsRS constructs in the two nrsRS promoter orientations in WT and NiCoZia strains. by Gábor Patyi (11846776)

Increased endodiastolic volume and decreased ejection fraction in GJB4-deficient zebrafish. by Ryuji Okamoto (614374)

Decreased remyelination initiation is observed in Scribble cKO mice following focal demyelination in corpus callosum. by Andrew A. Jarjour (343100)

“…In the contralateral (unlesioned) hemisphere (CL), no difference was seen in the proportion of axons in the corpus callosum that were myelinated in Scribble cKO compared to wild-type animals (A–C). Fewer remyelinated axons were observed in corpus callosum in the lesion area in Scribble cKO mice (E) relative to controls (D) as quantified in F; 0.4–0.5 μm: WT = 80.0% ± 9.8%, cKO = 41.3% ± 8.9% myelinated; 0.5–0.6 μm: WT = 79.4% ± 6.3%, cKO = 41.5% ± 9.5% myelinated; 0.6–0.7 μm: WT = 91.6% ± 3.0%, cKO = 44.3% ± 8.7% myelinated; >0.7 μm: WT = 92.7% ± 1.9%, cKO = 47.9% ± 2.5% myelinated. …”

A homozygous point mutation in the <i>Mrps34</i> gene causes a decrease in the MRPS34 protein. by Tara R. Richman (713532)

“…The 5′- and 3′-untranslated regions are shown as grey boxes and the predicted mitochondrial targeting sequence is shown as a black box (predicted using MitoProtII, [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005089#pgen.1005089.ref040" target="_blank">40</a>]). …”

CX3CR1-/- primary microglia show decreased antigen processing in <i>in vitro</i>. by Aaron D. Thome (813759)

“…<p>(A) Antigen processing of DQ Ovalbumin (red) is decreased in CX3CR1-/- primary microglia compared to WT primary microglia following a 30 minute treatment. …”

<i>Dmd^mdx</i> rats are characterized by muscle weakness and by a decrease in a spontaneous activity. by Thibaut Larcher (331981)

“…<i>Dmd^mdx</i> rats showed fatigue with a decreased force grip across the five pulls, and significant values are obtained for the two last trials that were reduced to ∼70% when compared to Trial 1. …”

Removal of <i>Mcs5c</i> TCE copies results in decreased <i>Pappa</i> expression <i>in vitro</i>. by Amanda N. Henning (3043851)

Impaired glucose metabolism and decreased insulin sensitivity in isolated adipocytes of Nscl-2−/−, Nscl-2−/−×ob/ob mice and controls. by Karen Ruschke (372824)

Gene expression analysis of T3-regulated genes <i>Dio1</i>, <i>Gsta2</i> and <i>Ucp2</i> in the liver and <i>Hcn2</i>, <i>Atp2a2</i>, <i>Myh6 and Myh7</i> in heart of vehicle treat... by Soledad Bárez-López (607514)

HIV-1 CA mutations selected during passage in rhTRIM5α-expressing cells decrease sensitivity to rhTRIM5α. by Steven J. Soll (270043)

The increased <i>in vitro</i> phagocytic activity of resKCs and recMφs against FITC-<i>E</i>. <i>coli</i> and the decreased TNF-α production by LPS-stimulated liver MNCs following... by Takuya Ishikiriyama (6735674)

Image 2_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Methods<p>Mice were inoculated with 10⁷ CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. On day ten, mice were inoculated with 10⁵ PFU WT HSV-2 333 and survival, pathology, and viral titers were assessed. …”

Motion of C1-GAP domain of WT and mutant RhoGAPs interacting with RhoA substrate. by Zen Kouchi (14898435)