E2 induces increased chromosome conformation capture contact frequencies but decreased proximity between enhancers and promoters. by Luciana I. Gómez Acuña (18605719)

Decreased RNA Polymerase II Occupancy at Promoters and Coding Regions of Genes Down-Regulated in SCA7 Mice by Dominique Helmlinger (72526)

“…<p>(A–F) ChIP assays were performed using formaldehyde-fixed chromatin extracts of retina from 2-mo-old control (WT or R7N; dark grey) and R7E (light grey) mice. …”

All Ca_V3.3 variants left-shift the voltage dependence of inactivation. by Yousra El Ghaleb (22075892)

Subjects:

A homozygous point mutation in the <i>Mrps34</i> gene causes a decrease in the MRPS34 protein. by Tara R. Richman (713532)

“…The 5′- and 3′-untranslated regions are shown as grey boxes and the predicted mitochondrial targeting sequence is shown as a black box (predicted using MitoProtII, [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005089#pgen.1005089.ref040" target="_blank">40</a>]). …”

Reduction of GCC signaling decreases membrane-associated TJPs in IEC monolayer. by Xiaonan Han (231176)

NBCe1 protein expression regulation by D₁-like (D₁R and D₅R) dopamine receptor agonist in hRPTCs carrying wild-type (WT) <i>SLC4A5</i>. by John J. Gildea (845025)

“…<p>NBCe1 protein expression is decreased following an increase in intracellular sodium (↑Na⁺) (10 μmol monensin/L, 24 h) (N = 4, *P<0.001 vs VEH, one-way ANOVA, Tukey’s test) in WT <i>SLC4A5</i> hRPTC. …”

<i>Dmd^mdx</i> rats are characterized by muscle weakness and by a decrease in a spontaneous activity. by Thibaut Larcher (331981)

“…<i>Dmd^mdx</i> rats showed fatigue with a decreased force grip across the five pulls, and significant values are obtained for the two last trials that were reduced to ∼70% when compared to Trial 1. …”

<i>shk-1</i> mutants display decreased glycogen storage. by Longjun Pu (20685717)

Decreased ATP sensitivity in both hetDel and hetT, del channels. by Yu-Wen Lin (410443)

Bone Formation and bone turnover is decreased in Ts65Dn Mice. by Tristan W. Fowler (143286)

Decreased Aβ42 halo overlaps with the decreased incidence of DNs in FO treated mice. by Milena Jović (6707702)

“…(E-H) In the FO-treated 5xFAD animals the decreased surface of the Aβ halo overlaps with the decreased incidence of swollen, dystrophic neurites.…”

Calpain protein expression level and enzyme activity are decreased in calpain mutants. by James B. Reinecke (346003)

Blocking C5L2 decreased MPO concentration in the supernatant of C5a-primed neutrophils. by Jian Hao (160736)

GluN2A(D731N) enhances sensitivity to endogenous proton and zinc ions. by Kai Gao (120150)

“…Di-heteromeric (h2A-D731N), one-copy and two-copy mutant tri-heteromeric (D731N/2A and D731N/D731N) receptors show a decreased current ratio, indicating enhanced proton sensitivity. …”

Anti-AT prophylaxis decreases lesion size in <i>S. aureus</i> dermonecrosis. by Christine Tkaczyk (465528)

Survivin deletion in beta cells leads to decreased beta-cell mass. by Xiaohong Wu (147036)

“…<p>(a) Male and female mutant mice exhibit decreased beta-cell mass at 2-month of age as compared to controls (n = 5 per genotype). …”

BBR decreased fasting blood glucose without improvement in insulin sensitivity. by Xuan Xia (356454)

Importance of HIF-1α and TET2/3 in CoCl₂-mediated induction of WT1 and WT1 lncRNA. by Gregory McCarty (708081)

Subjects:

GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

“…<p>(<b>A,B</b>) Representative TEVC recordings obtained from oocytes expressing WT GluN1/GluN2A (WT 2A) receptors (<b>A</b>) and GluN1/GluN2A(D731N) (2A-D731N) receptors (<b>B</b>) in which the currents were evoked by increasing concentrations (μM) of glutamate (in the presence of 100 μM glycine) at the holding potential of -40 mV. …”

Decreased renal fibrosis in the absence of IL-17 receptor on myeloid cells. by Shuwang Ge (470987)