Pharmacologic blockade of 5LO modulates tau metabolism, ameliorates synaptic integrity and decreases neuroinflammation in the 3×Tg mice. by Jin Chu (358006)

Incorporating a social responsibility goal in the prompt causes overleverage in utilities (A) and decreases risk of low ESG rating (B) (Study 3). by Philipp Winder (21615570)

Impact of MK2-deficiency on adipose tissue inflammation. by Jan Freark de Boer (631340)

Subjects:

Stability parameters for SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

Kinetic parameters of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

M^pro confers a significant reduction in growth in yeast caused by decreases in a variety of cellular proteins. by Jin Ou (16914305)

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…^†These substitutions resulted in a k_d >4X that of WT-FVIII-C2 for BO2C11 or abrogated binding to BO2C11. …”

Altered energy expenditure and decreased respiratory exchange ratio in Y1Y5^−/− mice on chow. by Amy D. Nguyen (153830)

Decreased production of antiviral factors in patients infected with SARS-CoV-2 due to reduced TLR7 expression by Julia Cataldo Lima (22811497)

“…<p>The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic presents a major global health challenge. …”

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity-5 by Rodrigo A Fuentealba (77901)

“…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”

Decreased copper content and activity/expression of SOD1 in circulating erythrocytes from <i>ms/−</i> mice. by Małgorzata Lenartowicz (150659)

“…<p>(<b>A</b>) Decreased copper content in erythrocytes of <i>ms/−</i> mice. …”

Purified serum IgG from SPMS patients decreased the amount of claudin-5 protein, and IgG from all clinical subtypes of MS patients increased the amount of VCAM-1 protein in TY09 ce... by Fumitaka Shimizu (545145)

“…(G) The amount of VCAM-1 protein in the TY09 cells was significantly increased after exposure to the purified IgG fraction from patinets with all clinical subtypes of MS, whereas it was not changed by the IgG from healthy controls, as determined by a Western blot analysis. (H) The TEER value of the TY09 cells was significantly decreased after exposure to the purified IgG fraction from SPMS patients, although it was not changed by incubation with the purified serum IgG fractions from RRMS-R or RRMS-S patients, or from healthy controls (mean ± SEM, SPMS n = 6, RRMS-R n = 4, RRMS-S n = 6, Normal n = 5). …”

Lack of PD-L1 expression by host tissues increases numbers of activated donor T cells but decreases donor Tregs in spleen. by Mohammad S. Hossain (415643)

Decreased osteoclasts invasion into bony defects of <i>db-/db-</i> mice. by Christoph Wallner (699861)

“…<p>(A) TRAP stainings of <i>db</i>^-/<i>db</i>^- and WT mice 7dpO revealed that osteoclasts invasion is decreased in <i>db</i>^-/<i>db</i>^- mice (arrows indicate TRAP-positive pixels) which could be confirmed by quantification of TRAP-positive pixel in the defect area (B). …”

Three variants lower the rheobase and increase firing frequency of Ca_V3.3, while the A398V variant shows the opposite effect. by Yousra El Ghaleb (22075892)

Subjects:

IL-8 secretion decreased from TLR5 silenced (siRNA) Caco-2BBe cells exposed to flagellin. by Tonyia Eaves-Pyles (344135)

“…<p><b>A. </b><i>S. dublin</i> flagellin was added to the AP or BL surface of polarized Caco-2BBe cells where TLR5 was knocked down using siRNA. …”

Treatment with rVP1 decreases NF-κB activation that modulates CCL2 production. by Tai-An Chen (211390)

Inhibition of F/P tyrosine kinase by imatinib in CEL patients decreased phosphorylation of JAK2, Stat3 and Stat5 in a time-dependent manner. by Bin Li (39349)

Graphs of marginal mean values of the studied parameters for dolphin kick, flutter kick and breaststroke kick with and without diving gear (Parameters that were not statistically d... by Marek Rejman (9199616)

<i>Ubr5</i>^<i>mt</i> synovium exhibits markers of increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)