GPI anchored proteins are required for neural differentiation. by Xuan Yuan (225365)

“…Neural induction and rosette formation upon neural induction was assessed in three cell lines using a serum-free EB generation method. On day 2 (left) of hiPSC-derived EBs from <i>PIGA</i>wt, <i>PIGA</i>c.1234C>T, and <i>PIGA</i>null after forced aggregation (20X magnification, scale bar is 50μm). …”

MMR components affect the silencing at both mating-type and telomere loci. by Qian Liu (135614)

“…<p><b>(A)</b> MMR deletion strains (WT(<i>his3Δ</i>), <i>pms1Δ</i>, <i>mlh1Δ</i>, and <i>msh2Δ</i>) showed decreased mating-type cassette silencing. …”

In vivo assessment of 5-HT_1A and 5-HT₂ post-synaptic receptor function using 8-OH-DPAT-induced change of corticosterone levels and DOI-induced head-twitches. by Thibault Renoir (348572)

DataSheet_1_Effectiveness, safety and pharmacokinetics of Polo-like kinase 1 inhibitors in tumor therapy: A systematic review and meta-analysis.docx by Xiao Wei (44054)

“…Rigosertib (ON 01910.Na) was associated with a decreased risk of AEs in digestive system (ES, 0.103; 95% CIs, 0.059-0.147), but BI 2536 and Volasertib (BI 6727) increased risk of AEs in blood system (ES, 0.399; 95% CIs, 0.294-0.504). …”

DataSheet1_Efficacy and Safety of DL-3-n-Butylphthalide in the Treatment of Poststroke Cognitive Impairment: A Systematic Review and Meta-Analysis.docx by Xueming Fan (11998772)

“…</p><p>Result: We identified 26 studies with a total sample size of 2,571 patients. The results of this study showed that NBP as monotherapy or combination therapy had better performance in increasing the MoCA (monotherapy: SMD_N = 1.05, 95% CI [0.69, 1.42], p < 0.00001; SMD_P = 1.06, 95% CI [0.59, 1.52], p < 0.00001. combination: SMD_O = 0.81, 95% CI [0.62, 1.01], p < 0.00001; SMD_N = 0.90, 95% CI [0.46, 1.33], p < 0.0001; SMD_D = 1.04, 95% CI [0.71, 1.38], p < 0.00001), MMSE (monotherapy: MD_N = 4.89, 95% CI [4.14, 5.63]), p < 0.00001). combination: SMD_O = 1.26, 95% CI [0.97, 1.56], p < 0.00001; SMD_C = 1.63, 95% CI [1.28, 1.98], p < 0.00001; SMD_N = 2.13, 95% CI [1.52, 2.75], p < 0.00001) and BI (monotherapy: MD_N = 13.53, HKSJ 95% CI [9.84, 17.22], p = 0.014. combination: SMD_O = 2.24, HKSJ 95%CI [0.37, 4.11], p = 0.032; SMD_C = 3.36, 95%CI [2.80, 3.93], p < 0.00001; SMD_D = 1.48, 95%CI [1.13, 1.83], p < 0.00001); and decreasing the NIHSS (monotherapy: MD_N = −3.86, 95% CI [−5.22, −2.50], p < 0.00001. combination: SMD_O = −1.15, 95% CI [−1.31, −0.98], p < 0.00001; SMD_C = −1.82, 95% CI [−2.25, −1.40], p < 0.00001) and CSS (combination: MD_O = −7.11, 95% CI [−8.42, −5.80], p < 0.00001), with no serious adverse reactions observed. …”

M-TUBE is a fabrication-free, microfluidics tubing-based bacterial electroporation device that is simple to assemble and exhibits higher electroporation efficiency than cuvettes. by Po-Hsun Huang (183737)

“…Transformation was dependent on the electric field. For M-TUBE devices, a voltage of ±2.50 kV (AC field) was applied, which results in an electric field of 8.33 kV/cm. …”

DataSheet_2_Effectiveness, safety and pharmacokinetics of Polo-like kinase 1 inhibitors in tumor therapy: A systematic review and meta-analysis.pdf by Xiao Wei (44054)

“…Rigosertib (ON 01910.Na) was associated with a decreased risk of AEs in digestive system (ES, 0.103; 95% CIs, 0.059-0.147), but BI 2536 and Volasertib (BI 6727) increased risk of AEs in blood system (ES, 0.399; 95% CIs, 0.294-0.504). …”

Data_Sheet_1_Strict forest protection: A meaningful contribution to Climate-Smart Forestry? An evaluation of temporal trends in the carbon balance of unmanaged forests in Germany.d... by Rouven Nagel (7071380)

“…Carbon stocks in newly unmanaged forests increased almost linearly for approximately 50 years after cessation of management. Subsequently, a stabilization or medium-term decrease in carbon stock was observed, likely due to the initiating transition from even-aged to multi-aged structures. …”

<i>Ssdp</i> knockdown and overexpression cause autism-like behavioral deficits in <i>Drosophila</i>. by Safa Salim (9186786)

The Catalytic Subunit of the System L1 Amino Acid Transporter (<i>Slc7a5</i>) Facilitates Nutrient Signalling in Mouse Skeletal Muscle by Nadège Poncet (527942)

“…These changes were associated with >50% decrease in S6K Thr389 phosphorylation in muscles from MS-<i>Slc7a5</i>-KO mice, indicating reduced mTOR-S6K pathway activation, despite no significant differences in lean tissue mass between groups on the same diet. …”

Table_2_Dietary intervention improves metabolic levels in patients with type 2 diabetes through the gut microbiota: a systematic review and meta-analysis.XLSX by Xiaoyu Xu (356293)

“…In addition, the high-fat and low-carbohydrate diet resulted in a notable decrease in Bacteroides abundance while simultaneously increasing the relative abundance of Eubacterium. …”

Table_1_Dietary intervention improves metabolic levels in patients with type 2 diabetes through the gut microbiota: a systematic review and meta-analysis.DOCX by Xiaoyu Xu (356293)

“…In addition, the high-fat and low-carbohydrate diet resulted in a notable decrease in Bacteroides abundance while simultaneously increasing the relative abundance of Eubacterium. …”

Table_1_Dietary intervention improves metabolic levels in patients with type 2 diabetes through the gut microbiota: a systematic review and meta-analysis.DOCX by Xiaoyu Xu (356293)

“…In addition, the high-fat and low-carbohydrate diet resulted in a notable decrease in Bacteroides abundance while simultaneously increasing the relative abundance of Eubacterium. …”

Table_2_Dietary intervention improves metabolic levels in patients with type 2 diabetes through the gut microbiota: a systematic review and meta-analysis.XLSX by Xiaoyu Xu (356293)

“…In addition, the high-fat and low-carbohydrate diet resulted in a notable decrease in Bacteroides abundance while simultaneously increasing the relative abundance of Eubacterium. …”

Table_1_A Novel Natural Antimicrobial Can Reduce the in vitro and in vivo Pathogenicity of T6SS Positive Campylobacter jejuni and Campylobacter coli Chicken Isolates.DOCX by Filip Sima (5726201)

“…Furthermore, the reduced adhesion and invasion is associated with a significant decrease in bacterial motility of both isolates (p < 0.05–p < 0.001) in vitro. …”

Image_2_A Novel Natural Antimicrobial Can Reduce the in vitro and in vivo Pathogenicity of T6SS Positive Campylobacter jejuni and Campylobacter coli Chicken Isolates.JPEG by Filip Sima (5726201)

“…Furthermore, the reduced adhesion and invasion is associated with a significant decrease in bacterial motility of both isolates (p < 0.05–p < 0.001) in vitro. …”

Image_1_A Novel Natural Antimicrobial Can Reduce the in vitro and in vivo Pathogenicity of T6SS Positive Campylobacter jejuni and Campylobacter coli Chicken Isolates.JPEG by Filip Sima (5726201)

“…Furthermore, the reduced adhesion and invasion is associated with a significant decrease in bacterial motility of both isolates (p < 0.05–p < 0.001) in vitro. …”

<i>T</i>. <i>spiralis</i> IIL ESP induced Caco-2 cell apoptosis stained by DAPI, Hoechst 33258 and TUNEL staining. by Qi Qi Lu (17721401)

The impact of sublethal effects of fungal infection on mosquito feeding biology. by Penelope A. Hancock (223305)

“…Lines represent varying sublethal effects of fungal infection on mosquito feeding biology, including no sublethal effects (solid lines), a 25% decrease in the daily probability of finding a blood meal () and a 25% increase in the duration of the non-host-seeking stage () in fungal pathogen-infected mosquitoes (dashed lines), a 50% decrease in and a 50% increase in (dotted lines), and a 75% decrease in and a 75% increase in (dot-dashed lines). …”

Whole-body SB transposon mutagenesis drives a diverse tumor spectrum in <i>Trp53</i> wild type and mutant mice. by Aziz Aiderus (5618408)