Summary of the in vitro and in vivo characterization of PCNA mutants. by Yearit Fridman (240019)

“…Growth rates similar to that of cells expressing WT PCNA are denoted as 1. Increase and decrease in affinity detected by Y2H or SPR assays are marked in bold.…”

Functional analysis of a random mutant library. by Miriam Kaltenbach (3204093)

“…Mutations are classified as strongly deleterious (>2-fold activity decrease relative to <i>wt</i>PTE), weakly deleterious (2-fold—1.3-fold decrease), neutral (<1.3-fold change), and positive (>1.3-fold increase). …”

VCC-induced in vivo pro-inflammatory response and toxicity are TLR-dependent. by Shraddha Gandhi (21001590)

“…<p>(A) Decrease in serum IL-6 levels in TLR1^-/-, TLR2^-/-, C3H/HeJ and MyD88^-/- mice, in comparison to that in the wild type (WT) mice upon intra-peritoneal administration of VCC. …”

MD simulation analysis of the Q144R and wild type CYP1B1 structure. by Antara Banerjee (12508)

“…<b><i>Panel B</i></b> shows the altered flexibility pattern of the Q144R mutant as compared to WT. The log₂ ratio is calculated as . …”

Protein expression in ramp GCN mutants. by William A. Barr (9396098)

“…Nucleotides conforming to G and C at positions 1 and 2 of codons (G1 and C2) are underlined. The right column indicates the increase or decrease compared to WT in the frequency of G1 and C2 in codons 3 through 8. …”

Evolution of hnRNPA1 IDR. by Simon M. Lichtinger (11326846)

“…<p><b>(A)</b> Typical GA progression for hnRNPA1. The fitness function [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009328#pcbi.1009328.e005" target="_blank">Eq (2)</a>] was evaluated at , and increases by ∼20% over 20 rounds, while maintaining population diversity. …”

The effector functions of CHK-152 contribute to protection <i>in vivo</i>. by Pankaj Pal (404355)

“…<p><b>A</b>. Comparison of binding of ch-CHK-152 and agylocsyl ch-CHK-152 N297Q to pE2-E1, as measured by surface plasmon resonance. …”

Fig S1. by Leonardo Santos (477304)

“…Black arrows indicate the formation of heteroduplexes, which are absent in the controls of uninduced and untransfected cells, as well as in induced but untransfected cells (Ctrl and Ctrl2, respectively). A noticeable decrease in amplicon yield suggests significant modifications following Cas9 cleavage and DNA repair processes. …”

Dopaminergic differentiation deficit persists at later stages in <i>Dkk1</i> mutants. by Diogo Ribeiro (230483)

“…Scale bar = 100 µm. (B) A 30% decrease in the number of dopaminergic neurons was detected at this stage (mean ± s.e.m- <b><i>Wt</i></b><b>:</b> 10640±1301 N = 4; <b><i>Dkk1^<b>+/−</b></i></b><b>:</b> 7262±616.9 N = 3). …”

Data_Sheet_1_Organic-Inorganic Hybrid Planarization and Water Vapor Barrier Coatings on Cellulose Nanofibrils Substrates.docx by Feyza Karasu (1909087)

“…The WVTR and oxygen transmission rate values of the hybrid coated CNF laminates were in the range 5–10 g/m²/day (at 38°C and 50% RH) and 3–6 cm³/m²/day/bar (at 23°C and 70% RH), respectively, which matches food and pharmaceutical packaging requirements. …”

Table_1_The Effects of Acute Aerobic Exercise on Blood Pressure, Arterial Function, and Heart Rate Variability in Men Living With HIV.DOCX by Juliana Pereira Barros (11136588)

“…NES; p < 0.05) reductions occurred in controls for SBP (∼10 mmHg, 2 h), DBP (∼6 mmHg, 20, 30, and 70 min), cSBP (∼9 mmHg, 30 min), cDBP (∼7 mmHg, 30 and 70 min), augmentation index (∼10%, 30 min), and pNN50 (∼20%; up to 2 h), while in MLHIV only cSBP (∼6 mmHg, 70 min) and cDBP (∼4 mmHg, 30 min) decreased. …”

Glycine negatively influences THN migration. by Ulrike Theisen (4734555)

“…(H) The hyperpolarizing effect of glycine depends on the co-expression of the channel KCC2. This gene is very weakly expressed in developing neurons as reported previously [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2002226#pbio.2002226.ref045" target="_blank">45</a>,<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2002226#pbio.2002226.ref046" target="_blank">46</a>], but could be observed in the spinal cord and the hindbrain of a 30 hpf wt embryo (top panel, bottom panel: sense probe for control). …”

SAHA specifically down regulates <i>Hdac7</i> mRNA levels. by Caroline L. Benn (195214)

“…(D) Representative western immunoblot of 50 µg of cortical homogenate from 14 week old wild-type (WT), R6/2, <i>Hdac7</i>+/− and R6/2-<i>Hdac7</i>+/− mice. …”

The response gains of inner and outer retina are differentially affected in D1−/− mice. by Quanhua He (487017)

“…<b>D:</b> The OPs/b-wave ratios of D1−/− mice normalized to WT controls showing a significant decrease of the response gains at the light intensities of 0.025–0.08 cd*s/m². …”

Effect of TAC on left ventricular hypertrophy and function as measured by Echocardiography. by Eman A. Hamad (316682)

“…Data was expressed as mean±SE *p<0.01 vs WT, n = 10–17. The basal fibrosis is no difference between WT and A_2A-R TG. …”

<i>C6ST</i>-1 mRNA or 6-sulphated GAGs were not expressed in <i>C6ST</i>-1 KO mice. by Rachel Lin (215087)

“…Removal of 6-suphated moieties, by treatment with chondroitinase ABC and chondro-6-sulfatase (lanes marked with “+”) before the conjugation with 2-aminoacridone, showed that a sharp decrease in band intensity at ΔDi-4S or ΔDi-6S position in WT samples. …”

Role of the −5 bp in <i>sodB</i> regulation. by Beth M. Carpenter (373215)

“…<p>WT G27, WT 26695, and the “−5 bp swap” strain were grown as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005369#s2" target="_blank">Materials and Methods</a>, and RNA was isolated under iron replete and iron-depletion shock conditions. …”

NGF failed to induce persistent mechanical allodynia in Sp4+/- mice. SNI Sp4+/- mice developed mechanical hypersenstivity. by Kayla Sheehan (6406898)

“…Following NGF paw injection, both Sp4+/- and wt. mice developed a transient decrease in thermal paw withdrawal latency at 2, 6 and 24 hours that returned to baseline at 48 hours. …”

Recombination DNA repair was impaired in <i>BRIT1</i>-deficient spermatocytes. by Yulong Liang (241535)

“…BRCA2 foci were formed intensively on bivalents at zygotene in WT (a) but not in the <i>BRIT1</i>^−/− zygotene (b). …”

Short telomeres worsen diabetes severity in Akita mice and cause β-cell loss. by Nini Guo (227926)

“…<p><b>A</b>. Two hour glucose tolerance test of Ins2^C96Y/WT mTR^−/−iG₄ with short telomeres shows more severe impairments compared with Ins2^C96Y/WT mice. …”