Table_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.XLSX by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Loss of intestinal epithelial Shh signaling deregulates intestinal crypt epithelial proliferation. by Jessica Gagné-Sansfaçon (571087)

“…Proliferation assays were performed by PCNA immunostaining (G and H, green labeling), with Evans blue serving as counterstain (red staining). Mutants displayed a decrease in cell proliferation as shown by a decrease in the number of PCNA-labeled proliferating cells (H) when compared to controls (G). …”

Displacement of site marker ligands bound to HSA in presence of increasing PS concentrations. by Shevin R. Feroz (468333)

“…Spectra marked as ‘a’, ‘b’, ‘c’ and ‘d’ refer to 10 µM BR, 10 µM HSA, 50 µM PS and PS–HSA (5∶1) complex, respectively. …”

Date palm wood flour/glass fibre reinforced hybrid composites of recycled polypropylene: Mechanical and thermal properties by AlMaadeed, Mariam A.

“…Addition of as little 5wt% glass fibre to wood flour reinforced RPP increases the tensile strength by about 18% relative to the wood flour reinforcement alone. …”
Get full text
Get full text
Get full text

Ionic-Liquid-Based Printable Materials for Thermochromic and Thermoresistive Applications by Liliana C. Fernandes (6711500)

“…Smart materials exhibiting thermochromic and themoresistive properties based on the electroactive polymer poly­(vinylidene fluoride) (PVDF) and the ionic liquid (IL) bis­(1-butyl-3-methylimidazolium) tetrachloronickelate ([Bmim]₂[NiCl₄]) have been developed with different contents of [Bmim]₂[NiCl₄] (10, 20, and 40 wt %) within the polymer matrix. …”

LZP attenuates AMFR-dependent apoB degradation. by Jiao-Xiang Wu (6323045)

“…(E) Overexpressed LZP did not decrease the apoB ubiquitination level in the absence of AMFR in HepG2 cells. …”

Ionic-Liquid-Based Printable Materials for Thermochromic and Thermoresistive Applications by Liliana C. Fernandes (6711500)

“…Smart materials exhibiting thermochromic and themoresistive properties based on the electroactive polymer poly­(vinylidene fluoride) (PVDF) and the ionic liquid (IL) bis­(1-butyl-3-methylimidazolium) tetrachloronickelate ([Bmim]₂[NiCl₄]) have been developed with different contents of [Bmim]₂[NiCl₄] (10, 20, and 40 wt %) within the polymer matrix. …”

Shh signaling is required for proper production of goblet cell secretory products and Paneth cell maturation. by Jessica Gagné-Sansfaçon (571087)

“…Immunostaining with an anti-lysozyme antibody showed a decrease in positively-labeled lysozyme cells (green staining) in mutant mice (E) compared to control littermates (D). …”

Differences in mean scores of upper extremity performance in all five accelerometer-derived variables across four time points- pre-HABIT, post-HABIT, 3-month, and 6-month post-HABI... by Shailesh S. Gardas (20490020)

table_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

table_2_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

Remodeling of Purkinje dendrites in the third postnatal week. by Megumi Kaneko (219519)

“…<b>D</b>: Overpassing branches per cell peak at P18, sharply decrease by P22 and plateau thereafter. <b>E</b>: The mean length of each dendritic branch decreases between P7 and P9, constantly increases until P35 and then slightly decreased by P50. …”

image_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.EPS by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

Expression of calpastatin in rhodopsin transgenic rats. by Jasvir Kaur (123596)

“…<p>(<b>A</b>) Immunoblotting for calpastatin showed decreased levels in both, P23H and S334ter rats. …”

ToxCast™Phase I chemical activity across cytotoxicity and differentiation ES cell assay endpoints. by Kelly J. Chandler (218453)

“…Unsupervised, two-dimensional hierarchical clustering of 320 ToxCast chemicals across four ES cell assay endpoints (cytotoxicity increase, cytotoxicity decrease, differentiation increase, differentiation decrease) and 4 doses each using Euclidean distance for measure and Ward's method for linkage analysis (A). …”

The exocyst is required for cell cycle progression in trypanosomes. by Cordula M. Boehm (3689848)

“…Sec15::RNAi cells have a ∼50% decrease to Sec15::HA 48h post induction, whilst expression of Exo99 remains stable, and <i>vice versa</i>. …”