(S)-2 induced growth arrest in LNCAP cells. by Anna Laurenzana (296271)

“…(<b>B</b>, middle) – Phase contrast pictures of companion cultures indicated that (S)-2 induced morphological changes and a marked decrease in cell density. (<b>B</b>, bottom) – Cells were treated with 2.5 µM drug for the indicated time points and p21 protein levels were monitored by immunoblotting; GAPDH was also examined to ensure equal loading of samples in each lane. …”

Differential selective pressure is acting on genes based on their centrality. by Nataša Puzović (7866440)

“…Genes with a selective pressure above 0.5 were categorized as responsive to selection. …”

DataSheet1_Using anti-Müllerian hormone to predict premature ovarian insufficiency: a retrospective cross-sectional study.docx by Yuanxin Huang (20286858)

“…At AMH level below 0.5ng/ml,basal FSH increased significantly with age. …”

Table1_The feasibility and safety of his-purkinje conduction system pacing in patients with heart failure with severely reduced ejection fraction.docx by Chengming Ma (15775178)

“…In addition, clinical and echocardiographic (≥5% improvement in LVEF or ≥15% decrease in LVESV) responses were assessed. …”

Presentation1_The feasibility and safety of his-purkinje conduction system pacing in patients with heart failure with severely reduced ejection fraction.pptx by Chengming Ma (15775178)

“…In addition, clinical and echocardiographic (≥5% improvement in LVEF or ≥15% decrease in LVESV) responses were assessed. …”

NK cells are affected differently by allogeneic grafts depending on the course of rejection. by Oliver Beetz (6786137)

“…The ratios of NK cells are presented as mean ± SEM of three (in D) and at least five (in B) recipients. …”

Image 1_Impact of strict IGF1 control on quality-of-life scores in patients with acromegaly.tif by Chaitanya Gandhi (20644727)

“…PASQ score decreased by 3.5 (p=0.02) and the ACRODAT^® overall status decreased by 50.5 (p=0.001); however, there was no difference in the AcroQoL score. …”

Neuronal migration defects in the cortex and hippocampus of <i>R402H/+; Emx1-cre</i> mice. by Ines Leca (9592316)

“…(F) Graph showing the distribution of BrdU+ cells in the different layers of the hippocampus of P10 mice (n = 5). <i>R402H/+; Emx1-cre</i> mutants show a significant accumulation of cells in the OL, accompanied by a decrease in BrdU+ cells in the PCL in comparison to controls. …”

Data_Sheet_1_Microgravity and Hypergravity Induced by Parabolic Flight Differently Affect Lumbar Spinal Stiffness.PDF by Jaap Swanenburg (4691752)

“…This was accomplished by measuring indicators of lumbar motor control, specifically lumbar spinal stiffness, activity of lumbar extensor and flexor muscles and lumbar curvature, in hypergravity and microgravity during parabolic flights. Three female and five male subjects participated in this study. The mean age was 35.5 years (standard deviation: 8.5 years). …”

Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma by Sigfus Gunnlaugsson (10358988)

“…A positive PSQ screen was associated with a 9.44 point (CI 5.54, 13.34, <i>p</i> < 0.001) lower ACT score for females and a 3.22 point (CI 0.56, 5.88, <i>p</i> = 0.02) lower score for males.…”

Data_Sheet_1_Immediate reduction in left ventricular ejection time following TAVI is associated with improved quality of life.docx by Jimmy Schenk (13807486)

“…Systolic, diastolic and mean arterial pressure, heart rate, and stroke volume increased immediately after TAVI (all p < 0.005), and left ventricular ejection time (LVET) immediately decreased with 10 ms (95%CI = −4 to −16, p < 0.001). …”

The combined effect of lifestyle intervention and antioxidant therapy on sperm DNA fragmentation and seminal oxidative stress in IVF patients: a pilot study by Peter Humaidan (454181)

“…The mean DFI decrease was 7.2% (95% CI: 4.8-9.5%; P <0.0001), whereas it was 0.42% (95%CI; -4.8 to 5.6%) in volunteers (P <0.00001). …”

Course of cerebral extracellular glucose and lactate/pyruvate ratio in insulin-treated SAH patients developing DIND by Florian Schlenk (46916)

DataSheet_1_Assessing risk from invasive alien plants in China: Reconstructing invasion history and estimating distribution patterns of Lolium temulentum and Aegilops tauschii.docx by Ming Yang (109148)

“…Using the optimal MaxEnt model, the geographical distributions of L. temulentum and A. tauschii were predicted based on screened species occurrences and environmental variables under the current and three future scenarios in the 2030s and 2050s (i.e., SSP1-2.6, SSP2-4.5, and SSP5-8.5).</p>Results<p>The mean AUC values were 0.867 and 0.931 for L. temulentum and A. tauschii, respectively. …”

Image_1_Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model.jpg by Xiali Zhong (8475186)

“…At therapeutic blood concentrations, which lie between 20 and 60 ng/ml, Paroxetine led to an 80% decrease in the expression of synaptic markers, a 60% decrease in neurite outgrowth and a 40–75% decrease in the overall oligodendrocyte cell population, compared to controls. …”

Image_3_Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model.JPEG by Xiali Zhong (8475186)

“…At therapeutic blood concentrations, which lie between 20 and 60 ng/ml, Paroxetine led to an 80% decrease in the expression of synaptic markers, a 60% decrease in neurite outgrowth and a 40–75% decrease in the overall oligodendrocyte cell population, compared to controls. …”

Image_2_Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model.JPEG by Xiali Zhong (8475186)

“…At therapeutic blood concentrations, which lie between 20 and 60 ng/ml, Paroxetine led to an 80% decrease in the expression of synaptic markers, a 60% decrease in neurite outgrowth and a 40–75% decrease in the overall oligodendrocyte cell population, compared to controls. …”

CM inhibits adhesion of U937s and adhesion molecule expression in PECs. by Shibani Pati (208746)

“…The cells were then collected and stained with fluorophore conjugated antibodies to I-CAM, V-CAM, E-selectin, and P-selectin. The cells treated with PEC/MSC conditioned media demonstrated decreased I-CAM and V-CAM expression compared to both those treated with PEC or MSC conditioned media(p<0.01, ANOVA). …”

Thyroid hormone (T₃) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy by Winifred W. Yau (5744939)

“…</p> <p><b>Abbreviations</b>: ACACA: acetyl-Coenzyme A carboxylase alpha; AMPK: AMP-activated protein kinase; <i>Acsl1</i>: acyl-CoA synthetase long-chain family member 1; ATG5: autophagy related 5; ATG7: autophagy related 7; ATP: adenosine triphosphate; BAT: brown adipose tissue; cKO: conditional knockout; COX4I1: cytochrome c oxidase subunit 4I1; <i>Cpt1b</i>: carnitine palmitoyltransferase 1b, muscle; CQ: chloroquine; DAPI: 4ʹ,6-diamidino-2-phenylindole; DIO2: deiodinase, iodothyronine, type 2; DMEM: Dulbecco’s modified Eagle’s medium; EIF4EBP1: eukaryotic translation initiation factor 4E binding protein 1; <i>Fabp4</i>: fatty acid binding protein 4, adipocyte; FBS: fetal bovine serum; FCCP: carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; FGF: fibroblast growth factor; FOXO1: forkhead box O1; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GFP: green fluorescent protein; <i>Gpx1</i>: glutathione peroxidase 1; <i>Lipe</i>: lipase, hormone sensitive; MAP1LC3B: microtubule-associated protein 1 light chain 3; mRNA: messenger RNA; MTORC1: mechanistic target of rapamycin kinase complex 1; NAD: nicotinamide adenine dinucleotide; <i>Nrf1</i>: nuclear respiratory factor 1; OCR: oxygen consumption rate; PBS: phosphate-buffered saline; PCR: polymerase chain reaction; PPARGC1A: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; <i>Pnpla2</i>: patatin-like phospholipase domain containing 2; <i>Prdm16</i>: PR domain containing 16; PRKA: protein kinase, AMP-activated; RPS6KB: ribosomal protein S6 kinase; RFP: red fluorescent protein; ROS: reactive oxygen species; SD: standard deviation; SEM: standard error of the mean; siRNA: small interfering RNA; SIRT1: sirtuin 1; <i>Sod1</i>: superoxide dismutase 1, soluble; <i>Sod2</i>: superoxide dismutase 2, mitochondrial; SQSTM1: sequestosome 1; T₃: 3,5,3ʹ-triiodothyronine; TFEB: transcription factor EB; TOMM20: translocase of outer mitochondrial membrane 20; UCP1: uncoupling protein 1 (mitochondrial, proton carrier); ULK1: unc-51 like kinase 1; VDAC1: voltage-dependent anion channel 1; WAT: white adipose tissue</p>…”

Table_1_Factors associated with initiation of pharmacological therapy and treatment changes in postural orthostatic tachycardia syndrome.docx by Samantha Jean Stallkamp Tidd (18854902)