Image_5_Schlafen family is a prognostic biomarker and corresponds with immune infiltration in gastric cancer.tif by Jiannan Xu (12282551)

“…Furthermore, Timer, TCGA, and TISIDB databases suggested that the SLFN5, SLFN11, SLFN12, SLFN12L, and SLFN14 expression in GC is highly linked with immune cell infiltration levels, immune checkpoint, and the many immune cell marker sets expression. We isolated three samples of peripheral blood mononuclear cell (PBMC) and activated T cells; the results showed the expression of SLFN family members decreased significantly when T cell active. …”

Data Sheet 1_Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice.pdf by Kaori Sakurai (1272567)

“…Additionally, we explored COX-2’s role in lipid metabolism.</p>Methods<p>Male A/J mice were exposed to sham air or mainstream cigarette smoke for 20 weeks. …”

Carbon stocks of three secondary coniferous forests along an altitudinal gradient on Loess Plateau in inland China by Ning Liu (168279)

“…Forest floor necromass decreased with increasing altitude across the three forests. …”

Beneficial Effects of Caloric Restriction on Chronic Kidney Disease in Rodent Models: A Meta-Analysis and Systematic Review by Xiao-meng Xu (840164)

“…Through the meta-analysis, we found that the parameter of blood urea nitrogen, serum creatinine and urinary protein levels of the AL group was significant higher than that of the CR group, which are 4.11 mg/dl, 0.08mg/dl and 33.20mg/kg/24h, respectively. …”

Anti-Obesity Effects of Granulocyte-Colony Stimulating Factor in Otsuka-Long-Evans-Tokushima Fatty Rats by Yonggu Lee (436856)

“…Given that leptin and CNTF play important roles in energy homeostasis and that obesity is an inflammatory condition in adipose tissue, we hypothesized that G-CSF could also play a role in energy homeostasis. …”

Table_8_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…We identify the temporal dynamics of the transcriptomic response to with more genes differentially expressed in the replicative and terminal phases than in the pre-replicative phase. …”

Data_Sheet_1_Temporal Bacterial Surveillance of Salmon Aquaculture Sites Indicates a Long Lasting Benthic Impact With Minimal Recovery.pdf by Joost T. P. Verhoeven (479712)

“…Samples within the high impact group were most often collected directly under cages, whereas those in the intermediate impact group were mainly sampled from 20 to 40 m from cages. Large scale phylum shifts (increases of Bacteroidetes, Firmicutes, Spirochaetes, and decreases in Proteobacteria and Epsilonbacteraeota) and a decline in bacterial diversity were observed in the high impact cluster, indicating significant ecological change. …”

Anticardiolipin (aCL) in sera from periodontitis subjects activate Toll-like receptor 4 (TLR4) by Harvey A. Schenkein (5728673)

“…<div><p>Anticardiolipin antibodies (aCL) have been reported to be present in 15–20% of sera from subjects with periodontitis at concentrations exceeding those found in 95% of the healthy adult population. …”

Data_Sheet_1_Analysis of COVID-19-Related RT-qPCR Test Results in Hungary: Epidemiology, Diagnostics, and Clinical Outcome.PDF by Katalin Gombos (10033505)

“…<p>Background: Effective testing is an essential tool for controlling COVID-19. We aimed to analyse the data from first-wave PCR test results in Hungary's Southern Transdanubian region to improve testing strategies.…”

Image_1_Risk of Developing Checkpoint Immune Pneumonitis and Its Effect on Overall Survival in Non-small Cell Lung Cancer Patients Previously Treated With Radiotherapy.PDF by Feliciano Barrón (6597104)

“…</p>Methods<p>In this retrospective trial, we included patients treated with second-line immunotherapy at the National Cancer Institute in Mexico City from February 2015 to February 2018. …”

Table_1_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…We identify the temporal dynamics of the transcriptomic response to with more genes differentially expressed in the replicative and terminal phases than in the pre-replicative phase. …”

Data_Sheet_1_Decadal Trends in the Migration Phenology of Diadromous Fishes Native to the Burrishoole Catchment, Ireland.PDF by Elvira de Eyto (410881)

“…The beginning of the upstream migration of trout to freshwater has advanced by 20 days, while the end of the run is more than one month later than in the 1970’s. …”

DataSheet_2_Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival.pdf by Eleanor R. Burgess (12300113)

“…In 37 samples (37 patients), median ascorbate content was 7.6 μg ascorbate/100 mg tissue, range 0.8 – 20.4 μg ascorbate/100 mg tissue. In tumours with above median ascorbate content, HIF-pathway activity as a whole was significantly suppressed (p = 0.005), and several members of the pathway showed decreased expression (carbonic anhydrase-9 and glucose transporter-1, both p < 0.01). …”

Table_2_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…We identify the temporal dynamics of the transcriptomic response to with more genes differentially expressed in the replicative and terminal phases than in the pre-replicative phase. …”

Image_1_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG by Hongmei Li-Byarlay (5227208)

“…We identify the temporal dynamics of the transcriptomic response to with more genes differentially expressed in the replicative and terminal phases than in the pre-replicative phase. …”

Rapid Anti-Inflammatory Effects of Gonadotropin-Releasing Hormone Antagonism in Rheumatoid Arthritis Patients with High Gonadotropin Levels in the AGRA Trial by Anita Kåss (812567)

“…</p><p>Methods</p><p>We report intention-to-treat post hoc analyses among patients with high gonadotropin levels (N = 53), i.e. gonadotropin levels>median, from our proof-of-concept, double-blind AGRA-study (N = 99). …”

Table1_Elevated methane alters dissolved organic matter composition in the Arctic Ocean cold seeps.DOCX by Muhammed Fatih Sert (9737762)

“…In contrast, the number of formulas decreased by 20% in samples not amended with methane, both from non-seep and seep locations. …”

Anemia prevalence in Georgian regions, 2019–2022. by Natia Skhvitaridze (17255812)

“…</p><p>Methods</p><p>We used data from the Georgian Birth Registry and included pregnant women who delivered between January 1, 2019, and August 31, 2022 (n = 158,668). …”

Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever by Liang Cui (446525)

“…Herein, untargeted liquid-chromatography mass spectrometry metabolomics of serum from patients with dengue fever (DF) and dengue hemorrhagic fever (DHF) in the febrile phase (<96 h) was used to globally probe the serum metabolome to uncover early prognostic biomarkers of DHF. We identified 20 metabolites that are differentially enriched (<i>p</i><0.05, fold change >1.5) in the serum, among which are two products of tryptophan metabolism–serotonin and kynurenine. …”

Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E by Maren Carstensen-Kirberg (726961)

“…We measured basal and glucose-stimulated insulin secretion at glucose concentrations of 2.5 and 20 mmol/l. …”