The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets حسب Cenciarelli, Carlo

"…In the last decade Stat3 has gained attention as therapeutic target in cancer but there is not yet any approved Stat3-based glioma therapy. Herein, we report that exposure to a Stat3/5 inhibitor, induced apoptosis either in shHes1-CSC or control cells. …"
احصل على النص الكامل

Solar hydrogen production via a samarium oxide-based thermochemical water splitting cycle حسب Bhosale, Rahul

"…The computational thermodynamic analysis of a samarium oxide-based two-step solar thermochemical water splitting cycle is reported. …"
احصل على النص الكامل
احصل على النص الكامل

Hemoglobin Oxidation in Stored Blood Accelerates Hemolysis and Oxidative Injury to Red Blood Cells. حسب Mustafa, Ibrahim

"…There was 0.85% RBC lysis, an approximately 20% decrease in percentage oxyhemoglobin, and a 14% increase in methemoglobin formation, which shows hemoglobin oxidation on day 28.  …"
احصل على النص الكامل
احصل على النص الكامل

Flexible impedance and capacitive tensile load Sensor based on CNT composite حسب Ahmad, Zubair

"…The increase in impedance of the cells is observed to be 2.0 times while the decrease in the capacitance is found to be 2.1 times as applied force increases up to 0.3 N. …"
احصل على النص الكامل
احصل على النص الكامل

Influence of the heteroatom on the optoelectronic properties and transistor performance of soluble thiophene-, selenophene- and tellurophene-vinylene copolymers حسب Al-Hashimi, Mohammed

"…We report the first soluble poly(3-dodecyl tellurophenylene-vinylene) polymer (P3TeV) by Stille copolymerization and compare its properties to the analogous thiophene and selenophene containing polymers. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications حسب Souayeh, Basma

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents حسب Ayoub, Abeer J.

"…Their IC50 values ranged from 1.2 to 9.04 µM for interleukin-6; from 1.5 to 19.3 µM for Chemokine (C-C) Ligand 2; from 2.4 to 5.2 µM for nitric oxide; and from 1.1 to 20.5 µM for prostaglandin E2. …"
احصل على النص الكامل
احصل على النص الكامل

Techno-economic assessment of upfront nitrogen removal in a baseload LNG plant حسب Pal, Ajinkya

احصل على النص الكامل
احصل على النص الكامل

Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security حسب Moulahi, Tarek

"…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect Of The Apical Ectodermal Ridge On Mitotic Index In Hind Limb Bud Mesenchyme In Bufo Regularis حسب Abdel Karim, Ahmed E.

احصل على النص الكامل

Effect of hyperglycemia on EPCs function and regenerative ability حسب Hendawi, Hadeel Khalil

"…This research aims to test the EPC subtype blood outgrowth endothelial cells (BOECs) and their ability to survive and function under chronic hyperglycemic conditions. For that, we studied BOECs viability, response to shear stress, angiogenesis ability, and barrier function under normoglycemic (5.5mM) and hyperglycemic (25mM) conditions. …"
احصل على النص الكامل
احصل على النص الكامل

Tailoring optical absorption in silicon nanostructures from UV to visible light: A TDDFT study حسب Hassan, Walid M.I.

"…(ii) The exciton binding energy is seen to decrease by approximately 45% from 0.67 eV to about 0.3 eV with length increase, for a nanostructure with a cross-section diameter of approximately 12 Å. …"
احصل على النص الكامل
احصل على النص الكامل

Enhancement of mechanical and corrosion resistance properties of electrodeposited NiP-TiC composite coatings حسب Fayyaz O.

"…Various amounts of TiC particles (0, 0.5, 1.0, 1.5, and 2.0 g L−1) were co-electrodeposited in the Ni–P matrix under optimized conditions and then characterized by employing various techniques. …"
احصل على النص الكامل
احصل على النص الكامل

Study on adaptive thermal comfort in Japanese offices under various operation modes حسب Takasu, Marina

"…The lower and upper limits of the optimum comfort temperature is approximately 23.5C and 26.6C in mixed-mode. In addition, it is seen that the optimum comfort temperature tends to increase and decrease at very low and high outdoor air temperatures respectively. …"
احصل على النص الكامل
احصل على النص الكامل

Effects of soaking, acidity and temperature on cadmium and lead removal from rice حسب Al-Naimi M.

"…Different rice treatments were involved i.e. three soaking times (0, 15, and 30 min), three temperatures (20, 25, and 30 �C) and four concentrations of glacial acetic acid (0.5%, 1%, 2%, and 3%). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…We also performed a virtual screening analysis with 19 AKT inhibitors obtained from the Selleck Chemicals website those satisfied the Lipinski rule of 5. …"
احصل على النص الكامل
احصل على النص الكامل

A decision support system for automating document retrieval and citation screening حسب van Dinter, Raymon

"…The proposed DSS is effective and can substantially decrease the document retrieval and citation screening steps' workload and error rate. 2021 The Author(s)…"
احصل على النص الكامل
احصل على النص الكامل

Convection In A Rotating Fluid Over A Sloping Bottom, With Application To The Arabian Gulf حسب Al Hajri, Khalid R.

"…To resolve sub-mesoscale phenomena we find it necessary to employ a model basin which is smaller in its horizontal dimension than the Arabian Gulf. …"
احصل على النص الكامل

Structural, wear and thermal behaviour of Cu–Al2O3–graphite hybrid metal matrix composites حسب Mittal, P.

"…Copper matrix composites with Al2O3–graphite reinforcement (0.5-0.5, 1.0-1.0, 1.5-1.5 and 2.0-2.0 wt%) were prepared by stir casting process. …"
احصل على النص الكامل
احصل على النص الكامل

Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression حسب Bhatti S.A.

"…This study aimed to evaluate the effect of dietary ochratoxin A (OA), in the presence and absence of L-carnitine (LC) and vitamin E (VE), on the humoral immune responses of White Leghorn cockerels (WLC). One-day old white male Leghorn chicks were divided into 12 groups, having 20 birds each and were offered ration contaminated with OA (1.0 or 2.0 mg/kg feed) alone and concurrently with LC (1.0 g/kg) and/or VE (0.2 g/kg), for 42 days. …"
احصل على النص الكامل
احصل على النص الكامل