GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

(a) Dependence of δ on η with κ = 2.0 by Shu-Wei Song (557396)

“…<p><strong>Figure 3.</strong> (a) Dependence of δ on η with κ = 2.0. (b) Dependence of δ on κ with η = 0.0096. …”

Severe decreases of TECs and impaired TEC expansion in the absence of mTORC1/Raptor. by Hong-Xia Wang (288934)

“…Data shown are representative or calculated from at least three experiments except E20, which was calculated from two experiments. Each circle or square represents one WT or <i>Rpt</i>^<i>f/f</i><i>-Foxn1Cre</i> mouse, respectively. *, <i>p</i> < 0.05; **, <i>p</i> < 0.01; ***, <i>p</i> < 0.001 determined by two-tail Student’s <i>t</i> test.…”

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…However, how global land use changes impact soil N supply and potential N loss remains elusive. By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”

Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

“…D) Effects of H-1152 and Y-27632 on the phase 1 and phase 2 TEER decreases induced by TNF. Starting at T₀, HDMEC plated on ECIS 96-well arrays received a 1 hour pre-treatment with vehicle (top panel, n = 4, 4) or with a ROCK inhibitor, either H-1152 (at 1 or 10 μM, middle panel, n = 6, 6) or Y-27632 (at 1 or 10 μM, bottom panel, n = 6, 6). …”

200 WT nts but not WT UTRs at each terminus are sufficient for efficient recovery of replicating virus. by Debarpan Dhar (724473)

Mice lacking the type 4 melanocortin receptor have a normal muscle fiber type distribution with a decreased resting heart rate. by Theodore P. Braun (228920)

“…<p>Skeletal and cardiac muscle was examined in in 11-week old male WT (n = 5) and MC4RKO (n = 6) mice. (<b>A</b>) Resting heart rate was decreased in MC4RKO mice. …”

RGS5 deletion resulted in decreased peripheral insulin sensitivity and suppressed the Akt/GSK3β signaling pathway in mice fed an HF for 24 weeks. by Wei Deng (17330)

Top 20 genes with increased and decreased expression in <i>Sdl</i> leukemias. by Bruce N. Bagley (123614)

TRAIL Is Decreased Before 20 Weeks Gestation in Women with Hypertensive Disorders of Pregnancy by Cheng Zhou (307152)

Fullerol treatment decreased the accumulation of leukocytes in the liver at 20 days after transplant. by Priscila T. T. Bernardes (559311)

Change relations between the dynamic deformation modulus and accumulative impact times under a confining pressure of 20 MPa. by Chun Wang (337817)

Requirement of NF-κB activation for cytokine-mediated reductions in TEER. by Paul R. Clark (714064)

“…Note that IL-1β over a 12 hour time course was ineffective at decreasing TEER in SR-IκB-transduced HDMEC. The corrected basal TEER for this experiment was 64.5 ± 2.8 Ω·cm² for SR-IκB-transduced HDMEC and 59.6 ± 1.1 Ω·cm² for vector control-transduced HDMEC. n = 3,3. …”

Expression of genes encoding proteins involved in protein folding, quality control, trafficking and ER-associated degradation differentially expressed in liver of <i>Fmo5</i><sup><... by Ian R. Phillips (5074121)

Expression of AC5 and AC6 in WT and AMPKα2-/- mice. by Anne Garnier (130125)

Subjects:

Apoptosis inhibitor prevented the decrease of IIL ESP-induced TJs expression and alleviated barrier disruption of Caco-2 monolayer. by Qi Qi Lu (17721401)

“…<p><b>A:</b> Apoptosis inhibitor Z-VAD-FMK pretreatment increased the IIL ESP-decreased TEER. …”

Image 5_Using sodium glycodeoxycholate to develop a temporary infant-like gut barrier model, in vitro.pdf by Francesca Bietto (21511316)

“…</p>Results<p>Our research demonstrates that GDC decreases Caco-2/HT29-MTX Trans-Epithelial Electrical Resistance (TEER) and increases paracellular permeability, without inflammation or cytotoxicity. …”

Blocking VIP-signaling decreased inflammation and necrosis in the liver and lung of mCMV-infected mice. by Jian-Ming Li (319425)

Decreased STAT3 and increased AMPK protein levels in NLRP3^−/− hearts. by Coert J. Zuurbier (313731)

Decrease of endogenous WT1 abundance by overexpression of zinc finger domain in breast cancer cells by Youqi Han (84352)