FLCN-deficiency leads to decreased Rho activity in sub-confluent cells and delays in wound closure. by Doug A. Medvetz (300145)

“…<b>B)</b> Rho activity was measured using a Rhotekin binding assay at 70% confluence. The FLCN-null UOK257 cells had a 2.5-fold decrease in active Rho levels (Rho GTP) compared to the FLCN re-expressing UOK257-2 cells (n = 3, p<0.05). …”

Expression of Egln3 decreases tumor aggression, increases survival and normalizes glioma vascular architecture. by Vicki A. Sciorra (312082)

Capzb2 coimmunoprecipitates with βIII-tubulin in brain lysates and decreases tubulin polymerization in vitro. by David A. Davis (239142)

“…(E) Capzb2 decreases the rate and the extent of tubulin polymerization in a concentration-dependent manner. …”

Decreased 11ß-HSD1 protein level by IGF-I overexpression <i>in vivo</i> and a direct treatment with IGF-I. by Subrata Chowdhury (787208)

“…<p><b>A</b>. IGF-I overexpression decreased the levels of 11ß-HSD1 in pancreatic islets, liver and visceral fat, shown in Western blots. …”

RNA integrity from rat PET blocks decrease depending on storage temperature. by Daniel Groelz (339304)

Increased accumulation of mutant huntingtin aggregates and decreased mobility of autophagosomes in the axon of AP-4 ε KO hippocampal neurons. by Raffaella De Pace (5147120)

Selective decrease in the frequency of miniature AMPAR-mediated EPSCs after application of AMPA. by Pontus Wasling (327604)

Increase of total proteinuria and decrease of renal function in mice lacking CD73. by Cornelia Blume (321209)

CNP decrease mitochondrial membrane potential and induce mitochondrial fragmentation in melanoma cells. by Elif Aplak (7430123)

“…<p>A, 300 μM CNP (4 h) significantly decreased mitochondrial membrane potential in A375 cells, but not in melanocytes, indicated by changes of TMRM dependent fluorescence in mitochondria. …”

Carbon monoxide (CO) decreases Nox4 activity and MMP-1 expression. by Francis Rousset (424375)

(A) Decreasing CaMKII activity by KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L) decreases spontaneous AP firing rate (n = 10 for each drug), cAMP (n = 4 for each drug) and ATP (n = 5 for each drug). by Yael Yaniv (162548)

Decreased Fhl1b activity augments induction of pancreatic endocrine cells. by Jin Xu (31283)

Reduction of IL-8 is associated with a relevant decrease of GBA2 expression in CF bronchial cells. by Nicoletta Loberto (2224150)

Decreased VLS and increased tumor regression in resveratrol-treated melanoma-bearing mice. by Hongbing Guan (248324)

Delayed viral clearance and decreased primary, memory and secondary responses in aged mice. by Tracy S. P. Heng (312700)

Neto1 Loss of Function Decreases tbLTP in CA1 Hippocampus by David Ng (266907)

Zinc accumulation upon ZnT2 overexpression decreases vesicular pH. by Yarden Golan (5924594)

Combined EGCG/As treatment increases ROS generation and decreases the activity of catalase but not SOD. by Jee-Youn Kim (796526)

The phagocytosis of polystyrene beads was most significantly decreased by anti-CD36 antibodies. by Refik Pul (292867)

“…<p>The MFI displays the amount of incorporated beads phagocytosed by 3×10⁵ cells. Data are expressed as means of the mean fluorescence intensities (MFI) ± SEM of three independent experiments. …”

CAK inhibition decreases gene transcription after UV-induced DNA damage. by Hany H. Arab (364331)