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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
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c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
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HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model
Published 2017“…The ability of tumor cells to modulate TME and to escape immune-mediated attack by releasing immunosuppressive cytokines has become a hallmark of breast cancer. Our study shows the effect of IV formulation of HET0016 (HPßCD-HET0016) a selective inhibitor of 20-HETE synthesis, administered intravenously in immune-competent in vivo mouse model of murine breast cancer. 4T1 luciferase positive cells were implanted to the mammary fat pad in Balb/c mice. …”