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40201
Presentation 3_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi...
Published 2025“…Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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40202
Data Sheet 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi...
Published 2025“…Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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40203
Data Sheet 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi...
Published 2025“…Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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40204
Presentation 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi...
Published 2025“…Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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40205
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40206
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40207
New [ONOO]-Type Amine Bis(phenolate) Ytterbium(II) and -(III) Complexes: Synthesis, Structure, and Catalysis for Highly Heteroselective Polymerization of <i>rac</i>-Lactide
Published 2014“…Complex <b>5</b> is a THF-solvated monomer. Each six-coordinated Yb<sup>III</sup> ion in both complexes adopts a distorted octahedron. …”
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40208
Probability of establishing a sylvatic ZIKV transmission cycle.
Published 2016“…Contour lines show 0.25, 0.5, 0.75, and 0.95 probability of establishment. …”
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40209
Molecular interactions of agonist and inverse agonist ligands at serotonin 5-HT<sub>2C</sub> G protein-coupled receptors: computational ligand docking and molecular dynamics studie...
Published 2015“…<div><p>To understand molecular determinants for ligand activation of the serotonin 5-HT<sub>2C</sub> G protein-coupled receptor (GPCR), a drug target for obesity and neuropsychiatric disorders, a 5-HT<sub>2C</sub> homology model was built according to an adrenergic β<sub>2</sub> GPCR (β<sub>2</sub>AR) structure and validated using a 5-HT<sub>2B</sub> GPCR crystal structure. …”
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40210
Example entropy time series with a change of heart.
Published 2020“…There is a marked v shape to the curve as the decoder entropy increases after input starts to become incompatible with the original target <i>s</i><sub><i>a</i></sub>, and then decreases as sb is approached.…”
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40211
ELISA quantification of soluble and insoluble Aβ in frontal and temporal lobes.
Published 2013“…Frontal (<b>G</b>) and temporal (<b>H</b>) cortices GDFA/GHCl-soluble Aβ<sub>42</sub>. There was a mean decrease in Bapi-AD Aβ<sub>42</sub> relative to NI-AD more noticeable in the latter than in the former. …”
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40212
Numerical evaluation of the thermal performance of a near-surface earth-to-air heat exchanger with short-grass ground cover: A parametric study
Published 2021“…By increasing the soil thermal conductivity from 1 to 5 W m−1 K−1 the outlet temperature decreased by about 4.4 °C.…”
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40213
Changes in the structure of the phytoplankton community in a Nile tilapia fishpond
Published 2018“…Results In the fishpond, we registered a 1.5 times increase in nitrogen and total suspended solids and a 2 times increase in phosphorous compared to the inflow water. …”
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40214
Altered Serum MicroRNAs as Novel Diagnostic Biomarkers for Atypical Coronary Artery Disease
Published 2014“…</p><p>Results</p><p>The TaqMan low density array and RT-qPCR analysis identified four serum miRNAs including miR-487a, miR-502, miR-208 and miR-215 that were significantly increased, while one miRNA, miR-29b, that was significantly decreased in ACAD patients compared with normal controls (<i>P</i><0.05). …”
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40215
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40216
Mmp14a knockdown results in embryos with microphthalmic eyes.
Published 2013“…<p><b>A–D</b> Analysis of eye size (<b>A, C</b>) and total body length (<b>B, D</b>) reveals a dose-dependent decrease in eye size after knockdown of Mmp14a with the ATG- (<b>A, B</b>) or the splice MO (<b>C, D</b>) at 5 dpf. …”
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40217
Seroprevalence of fourteen human polyomaviruses determined in blood donors
Published 2018“…For most polyomaviruses the observed seroprevalence was high (60–100%), sometimes slightly increasing or decreasing with age. Seroreactivity increased with age for JCPyV, HPyV6 and HPyV7 and decreased for BKPyV and TSPyV. …”
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40218
Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
Published 2016“…Furthermore, there was a dose-dependent down modulation of one of the two signalling subunits of the IL-2 receptor, the β chain (CD122) (mean decrease = 58.0%, SE = 2.8%, range 9.8%–85.5%, <i>n</i> = 33), on Tregs and a reduction in their sensitivity to aldesleukin at 90 min and day 1 and 2 post-treatment. …”
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40219
Supplementary Material for: Pure red cell aplasia induced by atezolizumab in a patient with small cell lung cancer successfully treated with steroid therapy: a case report
Published 2023“…PRCA is characterized by normocytic-normochromic anemia, a marked decrease in reticulocytes, and a decrease in bone marrow erythroblasts. …”
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40220
Coiled to Diffuse: Brownian Motion of a Helical Bacterium
Published 2012“…Moreover, the translational diffusion coefficients would have decreased by a factor of ∼1.5, if LI were rectified. …”