Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

“…Endogenous Beclin 1 ubiquitination level is decreased in Nedd4 siRNA-transfected rats (t_1,6 = 5.78, <i>p</i> = 0.001). …”

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

miR-146a and miR-155 levels decrease at the convalescent stage in patients with <i>V</i>. <i>cholerae</i> O1 infection. by Aziz Bitar (257322)

Δ<i>gra72</i> parasites form bubble vacuoles with decreased PVM permeability to small molecules. by Tatiana C. Paredes-Santos (16699433)

Bortezomib (PS-341) Treatment Decreases Inflammation and Partially Rescues the Expression of the Dystrophin-Glycoprotein Complex in GRMD Dogs by Karla P. C. Araujo (400323)

Expression of a 65kDa isoform of eIF2Bε leads to a global decrease in protein synthesis. by Lauren K. Brady (4479244)

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD8⁺ T_EM as compared to WT septic mice. by Katherine T. Fay (2576998)

“…<p>B6 and CD43^-/- mice were subjected to CLP and spleens were harvested at 24h and frequencies of apoptotic cells were assessed by 7-AAD and Annexin V staining. A, C) Representative 7-AAD and Annexin V staining of CD44^HI CD62L^LO CD4⁺ and CD8⁺ T_EM. …”

Decreased plaque size in ORP8 KO BM recipients and increased plaque macrophage content after 9 weeks WTD feeding. by Erik van Kampen (649704)

“…(N = 13 * P<0.05, data was analyzed by two-way ANOVA with Bonferroni post-tests) C) Collagen was visualized by staining plaques from ORP8 BM and WT BM recipients with a Masson's Trichrome (MTC) kit, but no difference was found between the groups (N = 15, significance was assessed by Student T test). …”

Average changes in (A) spontaneous AP firing rate, (B) ATP and (C) cAMP by decreasing CaMKII activity with KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L). by Yael Yaniv (162548)

p35 siRNA knockdown decreased Cdk5 activity, diminished WT1 expression and viable cell numbers, but did not affect a cell apoptosis marker as detected by WB. by Ya-Li Zheng (454837)

“…C. p35 siRNA reduced Cdk5 activity. D. Western blotting analysis showed a decline of WT1 expression in p35 siRNA podocytes (upper panel, lane 2 compared to lane 1, p = 0,048), but did not affect cleaved caspase 3 expression (middle panel, lane 2 compare with lane 1). …”

A Yoga Strengthening Program Designed to Minimize the Knee Adduction Moment for Women with Knee Osteoarthritis: A Proof-Of-Principle Cohort Study by Elora C. Brenneman (795723)

“…A secondary objective was to determine whether the program could improve mobility and fitness, and decrease peak KAM during gait. …”

Acetaldehyde decrease/eliminates C/EBP alpha binding to CTSL promoter sequence. by Riyaz A. Mir (350175)

Absence of LFA-1 results in decreased numbers of NKT cells within the regenerating liver. by Ann-Kathrin Jörger (3559358)

Deficiency of Nmnat3 in mice does not decrease the NAD level in mitochondria. by Masashi Yamamoto (407190)

Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

Subjects:

Inhibition of Rab5 Activity Decreases Fluid-Phase Uptake by Carsten Schnatwinkel (48)

WT data of set A398E/V and set M1425V/I pooled for better comparison. by Yousra El Ghaleb (22075892)

Subjects:

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA_A-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”

Blocking VIP-signaling decreased inflammation and necrosis in the liver and lung of mCMV-infected mice. by Jian-Ming Li (319425)