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Molecular dynamics, residue network analysis, and cross-correlation matrix to characterize the deleterious missense mutations in GALE causing galactosemia III.
منشور في 2021"…The three mutants were subjected to molecular dynamics simulation (MDS) with native protein for 200 ns using GROMACS. The MDS demonstrated that these mutations affected the beta-sheets and helical region that are responsible for the catalytic activity; subsequently, affects the stability and flexibility of the mutant proteins along with a decrease and more deviations in compactness when compared to that of a native. …"
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Improvement of both lipid and biomass productivities of Qatar Chlorocystis isolate for biodiesel production and food security
منشور في 2018"…Several strategies were developed to modulate and improve algae metabolites production to meet the requirements for biodiesel production. Most previous research evidenced that the increase of the lipid content is accompanied by a decrease of the biomass production, which increases the cost of the downstream processing. …"
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
منشور في 2025"…However, implementing interventions to decrease the T2D incidence, lower SBP, reduce the number of smokers, and improve the total cholesterol could yield gains of 200,408, 198,173, 194,725, and 113,462 PALYs, respectively. …"
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
منشور في 2023"…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …"
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A Multi-echelon Network Distribution Model For Emergency Resource Planning
منشور في 2014"…(Acknowledgement: Qatar/QNRF/NPRP Project: 5-200-5-027)…"
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Flight Scheduling in the Airspace
منشور في 2016"…This includes small (80 to 120 flights), medium (200 to 220 flights), and large (400 to 420 flights) instances. …"
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Economic-environmental analysis of combined heat and power-based reconfigurable microgrid integrated with multiple energy storage and demand response program
منشور في 2021"…The use of waste heat in combined heat and power (CHP)-based MG is more efficient to meet local load and decrease the emission pollution. …"
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Investigating the effect of polymer-modified graphene oxide coating on RO membrane fouling
منشور في 2022"…The membrane surface characterization showed a decrease in membrane surface roughness from 74.7 nm to 69.0 nm and an increase in membrane hydrophilicity as the contact angle decreased from 41.7 ± 4.50 to 22.0 ± 1.10. …"
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EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS
منشور في 2022"…We conducted random-effects meta-regressions to identify sources of heterogeneity and possible predictors of high prevalence. Results: The pooled-mean urogenital CT prevalence was 8.2% (95% CI: 7.5-9.1) for general populations, 14.0% (95%CI: 12.7-15.4) for female sex workers, 10.8% (95% CI: 8.4-13.4) for men who have sex with men, male sex workers, and transgenders, 16.1% (95% CI: 12.6-19.8) for symptomatic women, 25.4 (95% CI: 18.6-38.5) for symptomatic men, 9.7% (95%CI: 6.1-14) for HIV-positive individuals and individuals in HIV-discordant couples, and 11.9% (95 CI: 8.5-15.8) for STI clinic attendees. …"
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
منشور في 2017"…We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. …"
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
منشور في 2017"…We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. …"
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