HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

Mental distress (GHQ) on changes in economic activity since before the pandemic between April 2020 and July 2020 among UK young adults aged 16–34 in 2017–18. by Linruo Zhang (17200227)

Subjects:

Prolonged transforming growth factor (TGF)-βtreatment induced a decrease in total Smad2 and/or Smad3 in many cell strains by Kimberly A Brown (26546)

CXCL8 (2, 20, and 200 pg/ml) and CCL20 (5, 50, and 500 pg/ml) enhanced Ki-67 gene expression, but only 200 pg/ml of CXCL8 and 500 pg/ml of CCL20 enhanced early osteogenic marker ge... by Janak L. Pathak (759122)

HSP90 inhibition by RGRN-305 and 17-AAG decreased proinflammatory protein secretion. by Hakim Ben Abdallah (14578241)

Decrease in arginine and increase in citrulline after NEI-01 administration. by Jeremy P. H. Chow (8788208)

Telmisartan decreased NO production in LPS-stimulated BV2 and primary neonatal rat glial cells. by Nofar Torika (3169497)

CK2α decreases CLK transcription factor activity. by Áron Szabó (450885)

Exogenous FGF4 decreases osteogenic differentiation of mESCs. by Sung-Ho Kook (445098)

SLAP depletion decreases ubiquitination and degradation of Flt3 receptor. by Julhash U. Kazi (291273)

ngLVA degradation kinetics. by Nicole A. Grieshaber (11175417)

Exogenous activation of BMP signaling decreases apoptosis in POb cells. by Shuli Li (24534)

“…<p>(A) Histogram illustrating a time-course of Caspase-3 activity performed on FOb and POb cells undergoing osteogenic differentiation with or without exogenous BMP-2 (200 ng/ml). …”

LPS decreases only T cell proliferative response to OKT3. by Fanny Poujol (834338)

Sudachitin decreases osteoclastogenesis induced by RANKL in cultures of osteoclast precursors. by Yoko Ohyama (4775400)

Decreased CSF cytokine levels in α7 KO mice. by Feng Chi (170688)

Poly (I:C) decreases HIV-1 replication in PBMCs. by Christiane Rollenhage (762318)

Normal TLR4 and MD2 expression and decreased IL10 secretion and A20 expression by <i>cpdm</i> BMDC. by Zhe Wang (41178)

ATXN3 depletion decreases PNKP’s 3’-phosphatase activity. by Arpita Chatterjee (529752)

Cilostazol decreases OC formation and bone resorption induced by RANKL. by Ke Ke (583325)