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661
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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662
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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663
The investigation of treatment design parameters on carbon integration networks
Published 2023“…Furthermore, it was discovered that for net capture targets of 20% and 25%, no revenue from carbon storage could be generated beyond a solvent temperature of 25 °C. Additionally, the optimal diameter of the treatment column was more responsive to changes in solvent temperature for cases with low net capture targets (below 10%), while its sensitivity decreased for higher capture targets (above 10%). …”
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664
Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome
Published 2022“…Results: A total of 83 metabolites, mostly lipids, were significantly different (p < 0.05) between the two groups. Among lipids, 22 sphingomyelins were decreased in OBM compared to OBO. …”
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665
Repositioning of the global epicentre of non-optimal cholesterol
Published 2020“…These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. …”
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669
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Published 2017“…Study quality was assessed using a National Institutes of Health assessment tool. …”
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670
The influence of aeration scheme and aeration rate on the permeate flux for wastewater treatment using membrane bioreactors: Experimental and artificial neural network modeling
Published 2021“…Furthermore, a continuous and pulsed aeration scheme (5 min on and 5 min off) was tested. …”
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671
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Compressive SensingBased Remote Monitoring Systems for IoT applications
Published 2018“…The high energy consumption decreases the sensor's lifespan immensely, hence, a severe degradation in the overall performance of the REMS platform. …”
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674
Flight Scheduling in the Airspace
Published 2016“…The mathematical model has been solved using CPLEX 12.6 and the scatter search has been coded using C language under Microsoft Visual Studio v12 environment. The tests were conducted under a Windows 7 machine with an Intel Core i7 and 8 GB of RAM. …”
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675
INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS
Published 2015“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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676
Microstructure and compressive behavior of Al-Y2O3 nanocomposites prepared by microwave-assisted mechanical alloying
Published 2019“…The Al–1.5 vol. % Y2O3 nanocomposite exhibited the best ultimate compressive strength and yielded a strength of 359 ± 7 and 111 ± 5 MPa, respectively. …”
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677
Functionalization of silica-coated magnetic nanoparticles as powerful demulsifier to recover oil from oil-in-water emulsion
Published 2021“…The Fe–Si-MNP exhibited excellent %Soil, reliable stability, and high magnetization values ranging between 46.1 and 80.2 emu/g. adding a 5 nm silica layer on the surface of the Fe–Si-MNP (i.e., Fe–Si-1) protected them from oxidation conditions, extended their service life, and achieved a %Soil of ∼96.3%. …”
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680
Enhancing thermal and mechanical response of aluminum using nanolength scale TiC ceramic reinforcement
Published 2018“…the present work, nano-sized titanium carbide (0.5, 1.0 and 1.5 vol%) reinforced aluminum (Al) metal matrix composites were synthesized by powder metallurgy incorporating microwave sintering and hot extrusion. …”
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