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Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…MYBPC3 variants genotype–phenotype associations remain poorly understood. We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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242
Profiling of the Differentially Expressed Genes of Inflammation and Angiogenesis of Human Brain Microvascular Endothelial Cells Evoked by Cell Injury In-Vitro to Mimic Acute Ischem...
Published 2020“…Profiling of the gene expression revealed dysregulation of 20 genes (5 upregulated and 15 down regulated) of both inflammation and angiogenesis. …”
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A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
Published 2021“…Methods: This is a case series that includes 9 patients where we describe a technique that has the potential to enhance the survival of the first dorsal metacarpal artery (FDMA) flap and decreases the rate of distal necrosis via addition of a 5-mm skin bridge to the pedicle and by avoiding tunneling. …”
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245
Gender Prespecified Sampling for Cost Control
Published 2014“…The same question was asked among nonnationals and the split is almost the same: 54.5% of males prefer a male interviewer, whereas 5.2% of women prefer a male interviewer. …”
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Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar
Published 2014“…Results: Similar prevalence rates of HPV infection was identified in both Qatari and non-Qatari women at 6.2% and 5.9% respectively. HPV prevalence rate of 5.8% and 18.4% was identified in women with normal cytology and in women with abnormal cytology respectively. …”
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249
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…ResultsThe course included 18 participants (10 female, 8 males; average age 40.18 ± 8.46 years) categorized as novice (n = 10, <3 years’ experience), intermediate (n = 5, 3-5 years), and expert (n = 3, >5 years). Video evaluations did not reveal significant differences due to short-term training. …”
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Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
Published 2020“…BK altered the expression of 72 (4%) and 120 (6.5%) proteins, whereas leptin altered the expression of 189 (10.2%) and 127 (6.5%) proteins after 24 and 48 h, respectively, compared to control RASMC. …”
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The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio...
Published 2016“…The hemorrhage-induced vasodilation of the A3 and A4 arterioles was maintained during the post-resuscitation observation period in the CR (+55.3 ± 6.4%) and the vitasol groups (+39.5 ± 5.2%), but remarkably attenuated in the norepinephrine (+9.6 ± 5.8%) and vasopressin (+9.4 ± 8.8) groups. …”
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254
Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
Published 2016“…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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Urology Residents' Perspectives on the In-House On-Call Systems: A Study in an Accredited Academic Center
Published 2022“…Quality of life and education: We adopted a validated survey based on a 5-point Likert scale to assess the residents' perception of the transition to a 12-hour on-call system on their quality of life and education. …”
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Changes in air quality during the first-level response to the COVID-19 pandemic in Shanghai Municipality, China
Published 2020“…The results showed that air quality improved significantly During-FLR compared with Pre-FLR, with the concentrations of PM2.5, PM10, SO2, NO2, and CO all decreasing significantly. …”
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257
Regional Difference in the Association between the Trajectory of Selenium Intake and Hypertension: A 20-Year Cohort Study.
Published 2021“…The effect of selenium on hypertension is inconclusive. We aimed to study the relationship between selenium intake and incident hypertension. …”
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Energy recovery and nutrients recycling from municipal sewage sludge
Published 2020“…The maximum energy recovery (i.e., 59%) and maximum energy return on investment (i.e., 3.5) were obtained at 350 °C and 60 min of holding time. With the increase in HTL reaction time, the concentration of nitrogen in the APL increased (5.1 to 6.8 mg/L) while the concentration of phosphorus decreased (0.89 to 0.22 mg/L); the opposite was observed for the biochar. …”
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Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
Published 2024“…Results We found eight patients with unilateral acute cryptorchid TT with a prevalence of 8.9% (8/90) among all TT cases. …”
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Enhancement of Ethanol Production in Electrochemical Cell by Saccharomyces cerevisiae (CDBT2) and Wickerhamomyces anomalus (CDBT7)
Published 2019“…Local production and use of bioethanol supports local economies, decreases country's carbon footprint and promotes self-sufficiency. …”
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