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61
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate
Published 2020“…The lower reduction potential of copper ([Cu+(aq) + e− → Cu(s)], + 0.52 eV) compared to Ag ([Ag+(aq) + e− → Ag(s)], +0.80 eV) makes Cu(0) easily exchangeable by Ag+ ions via galvanic exchange without applying any external bias. …”
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Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity
Published 2023“…This is evidenced in the great ability of Pd/Ni-MOF-HNC to utterly oxidize CO at a lower complete conversion temperature (T100) of 114.5 °C compared with Pd/Ni-MOF-NC (153.8 °C) and Pd/C (201.5 °C) under atmospheric pressure. …”
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Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter...
Published 2022“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments
Published 2004“…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …”
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Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey.
Published 2020“…The association between egg consumption and diabetes is inconclusive. We aimed to examine the association between long-term egg consumption and its trajectory with diabetes in Chinese adults. …”
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67
Climatology and variability of wind speeds along the southwest coast of India derived from Climate Forecast System Reanalysis winds
Published 2022“…The study reveals significant decreasing trends in annual mean wind speeds, of the order of −2.0 to −2.5 cm·s−1·year−1, for the period 1979–2019. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…The incidence of overall bleeding and major bleeding were numerically higher for bridging group compared to non-bridging but did not reach statistical significance [(30.6% Vs 22.2%, p= 0.478) and (12.9% Vs 5.6%, p=0.375), respectively]. …”
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Socket Shield Technique to Improve the Outcomes of Immediate Implant: A Systematic Review and Meta-Analysis
Published 2023“…We used the GRADE approach to assess the certainty of evidence. …”
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Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor
Published 2013“…The TGA of the polymer blends reveals five-step degradation including four due to the pure polymer and one due to the blend formation. …”
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Osteoporosis in patients with stroke: A cross-sectional study
Published 2016“…However, the extent of decrease in bone mineral density (BMD) after stroke and all factors that influence such rapid bone loss are still not sufficiently explored. …”
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Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …”
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The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
Published 2021“…Random coefficient models determined relationships between Tc and COX/PGE2. Tc [mean (range)] increased in hot [+ 0.8 (0.4–1.2) °C; p < 0.0001; effect size (ES): 2.9], decreased in cold [− 0.5 (− 0.8 to − 0.2) °C; p < 0.0001; ES 2.6] and was unchanged in thermoneutral [+ 0.1 (− 0.2 to 0.4) °C; p = 0.3502]. …”
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Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat
Published 2011“…Normolipidemic and hyperlipidemic rats were administered a single intravenous dose of MDZ (5 mg/kg) with or without a single oral dose of racemic KTZ (40 mg/kg). …”
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
Published 2023“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan
Published 2020“…Over the past decade, the winter mean aerosol optical depth (AOD) values were in the range of 0.5–0.8, which is attributed to anthropogenic activities due to increase in urban development and economic growth in NE Pakistan. …”
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