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25 a » 2 a (Expand Search), 25 _ (Expand Search), 5 a (Expand Search)
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581
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582
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation-contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l-type Ca2+ (Cav1.2), sodium (NaV1.5) and potassium (KV7.1) channels. Many recent clinical and genetic studies have reported a series of CaM mutations in patients with life-threatening arrhythmogenic syndromes, such as long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). …”
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583
Carbon nanotube effect on the ductility, flexural strength, and permeability of concrete
Published 2019“…Concrete batches of 0, 0.03, 0.08, 0.15, and 0.25 wt.% CNTs were prepared using a mixing method that consisted of a 30-minute solution sonication and a 60-minute batch mixing. …”
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584
The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
Published 2017“…After 24 h of the administrations, inflammatory mediators such as interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-) and myeloperoxidase (MPO) enzyme as well as heme oxygenase (HO) activity were measured in both plasma and cardiac tissue, along with serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST). We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …”
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585
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586
Burden of disease attributable to suboptimal diet, metabolic risks and low physical activity in Ethiopia and comparison with Eastern sub-Saharan African countries, 1990-2015: findi...
Published 2018“…While the age-adjusted proportion of all-cause mortality attributable to CMU decreased significantly between 1990 and 2015, it increased from 10.8% [95% UI: 8.8-13.3] to 14.5% [95% UI: 11.7-18.0] for dietary risks and from 17.0% [95% UI: 15.4-18.7] to 24.2% [95% UI: 22.2-26.1] for metabolic risks. …”
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587
Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
Published 2015“…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …”
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588
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589
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590
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591
The investigation of treatment design parameters on carbon integration networks
Published 2023“…Furthermore, it was discovered that for net capture targets of 20% and 25%, no revenue from carbon storage could be generated beyond a solvent temperature of 25 °C. …”
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592
The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons
Published 2023“…In this study, a possible molecular mechanism of the 905 nm PBMT (0.25 W/cm2; 3, 6, 12, and 18 J/cm2, 5 Hz) analgesic effect was tested on 50B11 cells, by investigating its impact on mitochondria. …”
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593
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594
Prospects of Biocrude Production Potential from Local Diatom
Published 2020“…Next, Nitzchia reversa was harvested using a 25 m2 crossflow filtration membrane module. Crossflow harvested biomass slurry was centrifuged at 5000 RPM for 10 minutes to obtain a wet biomass paste containing 25 - 30% solid content. …”
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595
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596
Bryophyte cover and richness decline after 18 years of experimental warming in alpine Sweden.
Published 2020“…Deciduous shrub and litter cover had negative impact on bryophyte cover. We show that bryophyte species do not respond similarly to climate change. …”
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597
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598
Effect of the length of silicon nano-dot/wire on band gap
Published 2014“…We find that the band gap decreases with SNW length for the same diameter and approaches the band gap for an ideal infinitely long SNW. …”
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599
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600
Simulation and Optimization of an LNG Plant Cold Section
Published 2018“…Final LNG product comprised of 0.7 mol% nitrogen, 90.7 mol% methane, 5.6 mol% ethane, 2 mol% propane, 0.92 mol% butanes, at a temperature and gross heating value (GHV) of approximately − 161°C and 11.5 respectively. …”
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