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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
Published 2024“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
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A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
Published 2019“…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …”
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Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability
Published 2021“…OPC paste and mortar with TWW were first prepared and compared with the permissible limits specified in ASTM C1602/C1602M ? 18 provisions. After that, ten concrete mixes were prepared with different ratios of TWW (0%, 25%, 50%, and 100%), FA (0%, 20%, and 35%), and CN (0% and 3%) and tested for fresh slump and density, compressive and flexural strengths, electrical resistivity, porosity, and chloride permeability. …”
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Temperature sensor based on composite film of vanadium complex (VO2(3-fl)) and CNT
Published 2015“…DC and AC (100 Hz) resistances of the temperature sensor decreased quasilinearly with increasing the temperature in the range of 25-80 °C. …”
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Silicon Enhances Morpho–Physio–Biochemical Responses in Arsenic Stressed Spinach (Spinacia oleracea L.) by Minimizing Its Uptake
Published 2022“…Although, the activities of enzymatic antioxidants such as superoxidase dismutase, peroxidase, catalase, ascorbate peroxidase in the roots and shoots of the plants and non-enzymatic such as phenolic, flavonoid, ascorbic acid, and anthocyanin contents were initially increased with the exposure of 50 µM As, but decreased by the increasing the As concentration 100 µM in the soil. …”
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The investigation of treatment design parameters on carbon integration networks
Published 2023“…Furthermore, it was discovered that for net capture targets of 20% and 25%, no revenue from carbon storage could be generated beyond a solvent temperature of 25 °C. …”
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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
Published 2024“…We observed that the disease-associated K72I genetic variant had no apparent effects on the spectroscopic and catalytic properties of the full-length enzyme. …”
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Cyclic voltammetry and XPS studies of poly (aniline-co-3-aminophenol)
Published 2022“…In the electrochemical study, the copolymers differ from PA in the single-electron oxidation and reduction, reversibly at various scan rates ranging from 20 to 50 mV. The current density decreases from PA-co-3-AP20 to PA-co-3-AP80 by increasing the loading weight percentage of 3-aminophenol in the polymeric backbone. …”
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
Published 2017“…Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …”
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