Data Sheet 1_Morning cortisol as an indicator of arterial stiffness in patients with type 2 diabetes: prospective cohort study and Mendelian randomization study.docx Dahkki Zhuomeng Hu (16505950)

“…First, we used linear mixed-effects (LME) models and mediation analysis in a prospective cohort study (n=1,235; average follow-up of 3.5 years) in type 2 diabetes (T2D), featuring repeated brachial-ankle pulse wave velocity (baPWV) measurements (2–8 per participant; 4,143 total) to assess arterial stiffness. …”

Supplementary file 1_Towards standardizing mitral transcatheter edge-to-edge repair with deep-learning algorithm: a comprehensive multi-model strategy.docx Dahkki Silvia Corona (22678994)

“…</p>Conclusion<p>ECHO-PREP demonstrates the feasibility of an integrated AI-assisted workflow for MR assessment, combining quality control, dynamic 4D valve quantification, and scallop-level anatomy interpretation. …”

Supplementary file 1_Dynamic functional connectivity of the amygdala-hippocampal complex is associated with cognitive impairment in adolescents with Internet gaming disorder.docx Dahkki Tao Zhao (341704)

“…</p>Results<p>Three distinct connectivity states were identified, each characterized by unique network configurations. In State 2, dFNC strength between the AHC and both the attentional network (ATN) and visual network (VN) was positively correlated with T scores of the MATRICS Consensus Cognitive Battery (MCCB). …”

Table 5_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Table 2_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Image 3_Establishment and transcriptomic characterization of canine organoids from multiple tissues.jpg Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Table 1_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Image 2_Establishment and transcriptomic characterization of canine organoids from multiple tissues.jpg Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Table 7_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Table 3_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Table 6_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Image 1_Establishment and transcriptomic characterization of canine organoids from multiple tissues.jpeg Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Image 4_Establishment and transcriptomic characterization of canine organoids from multiple tissues.jpeg Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”

Table 4_Establishment and transcriptomic characterization of canine organoids from multiple tissues.xlsx Dahkki Christopher Zdyrski (11516168)

“…Introduction<p>Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved useful in biomedical research, rodent models often fail to adequately mimic human physiology and disease progression, resulting in poor preclinical prediction of therapeutic drug efficacy and toxicity. …”