Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem

“…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …”
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Changes in carbohydrate and nitrogen fractions during germination of fenugreek (Trigonellafoenum-graecum L.) seeds presoaked in GA3, growing under different osmotic potentials by Al Hadi, F.A.

“…The response of total nitrogen was variable; it increased considerably in -0.1 and -0.3 MPa osmotic potential, then dropped sharply at -0.5 and -0.8 MPa. …”
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway by Anwar, M. Akhtar

“…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …”
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Emerging clay-aryl-gold nanohybrids for efficient electrocatalytic proton reduction by Jlassi, Khouloud

“…Successful intercalation was confirmed by the detection of F1s peak in X-ray photoelectron spectroscopy (XPS) at ∼689 eV, in line with fluorine in CF bonds, and the reduction of gold (III) into metallic gold. …”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events by Raj, K. Diraviya

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Improving Concrete Durability by Using Optimized Aggregate Gradation and Reducing Cement Content by Chung, Hung-Wen

“…The main findings from this study are as follows: (1) The cementitious content of typical Florida pavement and structural concrete can be reduced by as much as 10 to 15% without loss in workability of the fresh concrete, and without decreasing the strength and durability of the hardened concrete. (2) Portlandlimestone cement (Type IL) can be used as a substitute for ordinary Portland cement (Type I/II). (3) The OAG technique can be used to efficiently reduce the cementitious content of the concrete mixes and to improve their performance."…”
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Bone benefits of fish oil supplementation depend on its EPA and DHA content by Abou-Saleh H.

“…Further, CFO supplementation was associated with an increase in the production of IL-10, IL-12, and IFN-γ and a decrease in the production of TNF-α and IL-6, and the activation of NF-κB, p38 MAPK, and JNK signaling pathways. …”
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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages by Al-Awad, Duha

“…We found that soluble uric acid enhanced autophagy flux in infected macrophages. We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …”
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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase by Abdulrahman N.

“…Cardiovascular diseases are the leading cause of death worldwide. One in three cases of heart failure is due to dilated cardiomyopathy. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Application of magnetic nanoparticles for the removal of oil from oil-in-water emulsion: Regeneration/reuse of spent particles by Elmobarak W.F.

“…The observed %Roil at a pH of 4 and Csur of 0.05 g/L was observed to be > 90 ± 0.1% and decreased by either rising the pH to 7 or increasing the Csur to 0.1 g/L. …”
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart by Akhtar, Saghir

“…Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …”
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Supramaximal-Exercise Training Improves Heart Rate Variability in Association With Reduced Catecholamine in Obese Adults by Jabbour, Georges

“…In this study, 19 OB [22.9 (8.4) years; body mass index (BMI) 33.4 (1.4) kg/m2] and 18 NW [23.2 (4.4) years; BMI 23.3 (1.2) kg/m2] adults completed a 6-week SET intervention. …”
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Morphology and property changes in PLA/PHBV blends as function of blend composition by Kanda G.S.

“…Both the tensile strength and Young?s modulus decreased with increasing PHBV content for the sequence of blends, and both parameters exhibited maximum values for 10?…”
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Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling by Alotaibi, Mohammed F.

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ELECTRODE SUSPENSION FOR AQUEOUS SODIUM FLOW BATTERY by MESLAM, MENTALLAH MOHAMED HASSANIN MOHAMED HASSANIN

“…In the current study, we attempt to formulate and characterize aqueous electrode suspensions (anolytes) composed of carbon black (KB) and sodium titanate (Na2Ti3O7; NTO) dispersed in branched micelle solution. …”
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A Model For A Narrow-Cut Fractionating Column by Farag, Hassan A.

“…The model was tested using different top pressures (5-30 psig), different feed temperatures (77-107T) and different reflux ratios (1:1 to 1:3). The most effective variable was found to be top pressure. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
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Seismic detection and characterization of a man-made karst analog - A feasibility study by Gritto, Roland

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A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge by Al Lahham, Salim

“…Distal necrosis of the patients in this study patients was compared with that in a control of 10 patients in whom we did the conventional FDMA flap. …”
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