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161
Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
Published 2020“…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …”
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162
Experimental and numerical investigation of the flexural behavior of one-way RC slabs strengthened with near-surface mounted and externally bonded systems
Published 2024“…In contrast, the slabs reinforced with EB experienced a decrease in ductility ranging from 38 % to 50 %. …”
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163
Thermodynamic analysis of solar-driven chemical looping steam methane reforming over Cr2O3/Cr redox pair
Published 2019“…The total solar energy required to drive the CS process (Q-solar-CS) rises by 1498.8 kW as the CH4/Cr2O3 molar ratio upsurges from 0.5 to 3. In case of the CSH process, when the TL increases from 500 to 1400 K, the Q solar CSH decreases by 54.5 kW and further surge in the TL from 1400 to 2050 K yields into upturn in the Q-solar-CSH by 108.5 kW. …”
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164
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165
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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166
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167
Application of Fe3O4 magnetite nanoparticles grafted in silica (SiO2) for oil recovery from oil in water emulsions
Published 2021“…Using an MDdose as low as 10 mg/L attained a %ηdem in the range of 93%–94.3% for O/W mixtures with Coil < 2000 mg/L, which slightly decreased to ∼90% for higher concentrations. …”
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168
Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Published 2018“…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …”
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169
Changes in carbohydrate and nitrogen fractions during germination of fenugreek (Trigonellafoenum-graecum L.) seeds presoaked in GA3, growing under different osmotic potentials
Published 1997“…The response of total nitrogen was variable; it increased considerably in -0.1 and -0.3 MPa osmotic potential, then dropped sharply at -0.5 and -0.8 MPa. …”
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170
Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
Published 2017“…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …”
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171
Emerging clay-aryl-gold nanohybrids for efficient electrocatalytic proton reduction
Published 2018“…Successful intercalation was confirmed by the detection of F1s peak in X-ray photoelectron spectroscopy (XPS) at ∼689 eV, in line with fluorine in CF bonds, and the reduction of gold (III) into metallic gold. …”
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172
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173
Improving Concrete Durability by Using Optimized Aggregate Gradation and Reducing Cement Content
Published 2020“…The main findings from this study are as follows: (1) The cementitious content of typical Florida pavement and structural concrete can be reduced by as much as 10 to 15% without loss in workability of the fresh concrete, and without decreasing the strength and durability of the hardened concrete. (2) Portlandlimestone cement (Type IL) can be used as a substitute for ordinary Portland cement (Type I/II). (3) The OAG technique can be used to efficiently reduce the cementitious content of the concrete mixes and to improve their performance."…”
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174
Bone benefits of fish oil supplementation depend on its EPA and DHA content
Published 2019“…Further, CFO supplementation was associated with an increase in the production of IL-10, IL-12, and IFN-γ and a decrease in the production of TNF-α and IL-6, and the activation of NF-κB, p38 MAPK, and JNK signaling pathways. …”
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175
The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
Published 2020“…We found that soluble uric acid enhanced autophagy flux in infected macrophages. We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …”
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176
Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
Published 2018“…Cardiovascular diseases are the leading cause of death worldwide. One in three cases of heart failure is due to dilated cardiomyopathy. …”
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177
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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178
Application of magnetic nanoparticles for the removal of oil from oil-in-water emulsion: Regeneration/reuse of spent particles
Published 2021“…The observed %Roil at a pH of 4 and Csur of 0.05 g/L was observed to be > 90 ± 0.1% and decreased by either rising the pH to 7 or increasing the Csur to 0.1 g/L. …”
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179
Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart
Published 2022“…Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …”
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180
Supramaximal-Exercise Training Improves Heart Rate Variability in Association With Reduced Catecholamine in Obese Adults
Published 2021“…In this study, 19 OB [22.9 (8.4) years; body mass index (BMI) 33.4 (1.4) kg/m2] and 18 NW [23.2 (4.4) years; BMI 23.3 (1.2) kg/m2] adults completed a 6-week SET intervention. …”
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