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we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
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Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability.
Published 2015“…Results are the mean ± SD of two independent experiments containing 8 replicates for each condition. * = <i>p</i><0.05, ** = <i>p</i><0.01, *** = <i>p</i><0.001, significant decrease compared to untreated cells (TA) or to siRNA Control (Kruskal & Wallis followed by Tukey and Dunnet test).…”
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143
A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population
Published 2015“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”
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Capzb2 coimmunoprecipitates with βIII-tubulin in brain lysates and decreases tubulin polymerization in vitro.
Published 2009“…<p>(A) In order to avoid overlap of the heavy chain signal (∼50 kDa) with the βIII-tubulin signal (∼55 kDa) in the immunoprecipitation using the Capzb2 monoclonal antibody (mAb), the antibody was coupled to the protein G/A beads through cross-linking. βIII-tubulin and Capzb2 signals were each detected following immunoprecipitation from brain lysate with both βIII-tubulin rabbit antibody (rAb)-coupled beads and Capzb2 mAb-coupled beads. …”
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Effects of siRNA TMPRSS2-ERG on ERG protein expression and cell viability.
Published 2015“…<p>VCaP cells were transfected for 24h, 48h and 72h with 50 nM of siRNAs TMPRSS2-ERG III (1, 2, 3), siRNAs TMPRSS2-ERG IV (1, 2), siRNA against ERG wild type or siRNA Control. …”
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<i>Ext1</i> mutant lungs exhibit a decrease in SHH-FGF10 signaling.
Published 2017“…The staining intensity was decreased in mutant lungs, indicating a decreased <i>Gli1</i> expression. …”
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Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>.
Published 2021“…The experiments were repeated 3 times. Each column represents the mean ± SD. …”
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Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer
Published 2015“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”
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FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells.
Published 2019“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD<sub>50</sub> = 8.4 μM, p ≤ 0.05). …”
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TUT1 suppression yields broad decreases in miRNA expression.
Published 2013“…Boxplots depict miRNA expression relative to negative control cells, which are depicted by the horizontal line at 1. Three enzymes–TUT1, PAPD4, and MTPAP–showed a significant, broad decrease in miRNA abundance (t-test, p-value <1×10<sup>−10</sup>). …”
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Table_3_Two Strains of Lactobacilli Effectively Decrease the Colonization of VRE in a Mouse Model.xlsx
Published 2019“…Defense-related genes such as defensin α, Apoa1, and RegIII were down-regulated in both FMT and the two Lactobacilli treatment groups. …”
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Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf
Published 2023“…</p>Methods<p>Bronchoalveolar lavage fluid (BALF) was collected from 50 children with CF aged 1, 3 or 5 years. BALF cells were analyzed using flow cytometry. …”