Knockdown of FOXO3a expression decreases Akt phosphorylation and PIK3CA mRNA expression. by Jie Chen (5892)

Subjects:

E₅₀ values. by Junxia Zhou (14381598)

“…The research results indicate that: (1) As the rock bridge angle increases, the secant modulus gradually decreases, following a power function relationship. (2) As the rock size increases, the secant modulus shows a trend of first decreasing and then stabilizing, following a power function relationship. (3) As the rock bridge angle increases, the characteristic tangent modulus and characteristic size gradually decrease, following a power function relationship. …”

JNK inhibitor AS601245 decreased levels of Bim and CC3 proteins and reduced neuronal apoptosis and brain infarct volume in P7 rat after HI. by Deyuan Li (769599)

“…<p>Samples were obtained from the cortex. Bim and CC3 protein levels were significantly reduced at 48 h in the AS601245-treated cortex compared with the DMSO-treated cortex (A). …”

Unilateral decrease of tracer-positive neurons after prion inoculation in the sciatic nerve. by Vladimir Ermolayev (260670)

Decrease in Vitamin D Status in the Greenlandic Adult Population from 1987–2010 by Nina O. Nielsen (490187)

“…<div><p>Background</p><p>Low vitamin D status may be pronounced in Arctic populations due to limited sun exposure and decreasing intake of traditional food.</p><p>Objective</p><p>To investigate serum 25(OH)D3 as a measure of vitamin D status among adult Inuit in Greenland, predictors of low serum 25(OH)D3 concentrations and the trend from 1987 to 2005–2010.…”

Developmental regulation of the decrease in adhesion. by Marco Tarantola (102609)

Subjects:

Factors associated with abnormal left ventricular ejection fraction (decreased or increased) in patients with sepsis in the intensive care unit by Dong Geum Shin (6019568)

“…Patients were classified into three categories according to LV EF (group 1 –[EF<50%, n = 36], group 2 –[50≤EF<70%, n = 252], and group 3 –[EF≥70%, n = 78]). …”

ku0063794 but not rapamycin decreased the TRPC6 mRNA levels in podocytes. by Fangrui Ding (659863)

“…(C) The TRPC6 mRNA levels were decreased in a concentration-dependent manner following treatment with 2, 3 or 4 µmol/l ku0063794. …”

Phosphorylation as an Effective Tool to Improve Stability and Reduce Toxicity of Antimicrobial Peptides by Zufang Ba (11036420)

“…The results showed that all phosphorylated peptides displayed reduced toxicity and enhanced stability compared to their unphosphorylated counterparts. Among them, W₃BipY₈-P stood out as the most promising peptide, exhibiting similar antibacterial activity as its unphosphorylated analog W₃BipY₈ but with significantly reduced hemolytic activity (19-fold decrease), cytotoxicity (3.3-fold decrease), and an extended serum half-life 6.3 times longer than W₃BipY₈. …”

NS affects the PI3K/AKT/mTOR pathway in RAW264.7 cells. by Yihua Wang (491766)

JNK inhibitor AS601245 significantly rescued the decrease in p-FOXO3a and attenuated FOXO3a translocation into nucleus after HI with no influence on p-Akt. by Deyuan Li (769599)

Decreased Risk of Ventilator-Associated Pneumonia in Sepsis Due to Intra-Abdominal Infection by François Philippart (319324)

“…The IAI group had fewer patients with VAP (56 [19.3%] <i>vs</i>. 806 [34.5%], <i>P</i><0.01) and longer time to VAP (5.0 <i>vs</i>.10.5 days; <i>P</i><0.01). …”

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by Sneha P. (3926957)

Subjects:

Nucleotide sequence changes in E6, L1 (MY), and LCR regions from A1/2, D2 and D3 HPV16 variants. by Ana Alfaro (280118)

The distributions of the end-simulation adolescence-limited proportion when (a) <i>k</i> is increased or decreased by 50%, (b) <i>c</i> is increased or decreased by 50%, (c) <i>γ</... by Jia Ning Leaw (752775)

Pharmacological inhibition of EGFR decreases reduces a subset of the inflammatory response at day 2 post-infection. by Marc Swidergall (185453)

Hcy decreased the level of H3K9me2 on the <i>COL1A1</i> promoter. by Wenjing Lei (772749)

Decreased survival of HL60 cells after fractionated irradiation. by Annette Geltmeier (779536)

Proliferative tissue degeneration is accompanied by a sustained decrease in proliferation, acute apoptotic responses, and progressive accumulation of DDR foci. by Catarina M. Henriques (102294)

“…<p>Representative immunofluorescence images of tissue sections in F1 <i>tert^−/−</i> and <i>tert^+/+</i> zebrafish show levels of proliferation (PCNA), apoptosis (TUNEL), DNA damage (53BP1) and senescence-associated β–galactosidase at the ages of 3 to c.12 months. Proliferative tissues such as A) testes, B) head kidney and C) gut sections show sustained significant decrease in proliferation in <i>tert^−/−</i> as compared to <i>tert^+/+</i> siblings (panels b, d and e) (p<0.001) and an acute apoptotic response at 3 months of age (p<0.001), which clears by c. 12 months (panels g, i and j). …”

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. by Daisuke Sugahara (2047696)