Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma by Munusamy, Shankar

“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro by Allouch, Soumaya

“…Similarly, the phosphorylation of AKT and P70S6K (a downstream target of mTOR) was increased by more than 1.5-fold in cells subjected to albumin treatment. …”
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Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications by Souayeh, Basma

“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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Overconfident results with the bivariate random effects model for meta-analysis of diagnostic accuracy studies by Furuya-Kanamori, Luis

“…Techniques specifically developed to combine independent studies of diagnostic accuracy and provide pooled estimates for sensitivity (Se), specificity (Sp), positive (pLR) and negative (nLR) likelihood ratios are relatively new. In 2001, Rutter and Gatsonis proposed the hierarchical summary receiver operating characteristic (HSROC) model,1 and in 2004 Macaskill described an empirical Bayes approach.2 Soon after, in 2005, Reitsma et al. proposed the bivariate random effects model,3 which has been widely adopted and is the most commonly used method for diagnostic meta-analysis.4 However, as pointed out by Diaz,5 the statistical performance of the bivariate model has not been scrutinized. …”
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Effect of hyperglycemia on EPCs function and regenerative ability by Hendawi, Hadeel Khalil

“…For that, we studied BOECs viability, response to shear stress, angiogenesis ability, and barrier function under normoglycemic (5.5mM) and hyperglycemic (25mM) conditions. The results have shown significant effects of chronic hyperglycemic conditions on cell proliferation (n=3, p<0.05), and migration (n=3, p<0.05) which were decreased when compared to control. …”
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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. by Marei, Hany E

“…The differentiation medium, containing cAMP, PDGFA, T3, and all-trans-retinoic acid (ATRA), promotes OBNSCs to generate mostly oligodendrocytes (OLs) displaying morphological changes, and appearance of long cytoplasmic processes. OBNSCs showed, after 5 days in OLs differentiation medium, a considerable decrease in the number of nestin positive cells, which was associated with a concomitant increase of NG2 immunoreactive cells and few O4(+)-OPCs. …”
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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy by Abdelaziz, Iman Ahmed

“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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Impact of combined oil-in-water emulsions and particulate suspensions on ceramic membrane fouling and permeability recovery by Abdalla M.

“…The addition of 1500 mg·L−1 of bentonite to a 10 vol.% emulsion resulted in a permeability decrease of 3.5–5 times over that recorded for the emulsion, and 8–36 times lower than that of the bentonite suspension. …”
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Prevalence of vincristine induced-peripheral neuropathy among Sudanese cancer patients by Imam, Ethar Abdelmageed

“…Twenty six (33.3%) of the patients took analgesic and 15.3% (n=12) experienced hypertension. …”
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Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan by Shahid, M. Z.

“…ir pollution during winters over north-eastern (NE) Pakistan (71–74.5 E, 28–34 N) is a major challenge that affects human health, climate and daily life. …”
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Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse by Ahmedna, Mohamed

“…Results show that cell viability decreased to 93 ± 3%, 83 ± 6%, 65 ± 4% and 39 ± 3% at 10, 25, 50 and 100 mM of glucose on day 1 with further drastic decrease in cell viability to 73 ± 5%, 61 ± 3%, 35 ± 2%, and 11 ± 6%, respectively, on day 4 compared to the untreated cell. …”
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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2. by Thirumal Kumar, D

“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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ASSOCIATION BETWEEN INSULIN RESISTANCE AND NITRIC OXIDE IN HUMAN RETINAL MICROVASCULAR ENDOTHELIAL CELLS IN VITRO by Bushra, Sumbul

“…This may suggest that insulin could counteract the hyperglycemic effect on AKT/PI3 kinase which mediates NO production and VEGF-A, with decreased adhesion molecules such as p-selectin that is involved in barrier disorder of retinal endothelial cells. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …”
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Acute and chronic toxicity assessments of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) on the calanoid copepod Acartia clausi: Effects on survival, development, sex-ratio and... by Emna, Djebbi

“…Lethal effects of estrogens on A. clausi life-stages (Embryos, one day old nauplii: N1, three day old nauplii: N3, copepodites: C1-C3 and adults: C6) were investigated using 48 h acute tests. …”
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Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Xue, Mingzhan

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Studies on growth and chemical composition of tobacco varieties. IV - comparative effects of various combinations of fertilizers on economic potentialities of tobacco plants by Younis, M. E. [محمود الباز يونس]

“…In two experiments, tobacco plants were treated with various combinations of ammonium nitrate (23% N) and compound C (3.5% N, 23% P and 16% K). At all levels used in experiment I, stem length and number of leaves were increased above the control values. …”
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Investigation of optimal charging locations for electric vehicles in Istanbul by Atilgan, B.

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Heat stress impairs proprioception but not running mechanics by Mtibaa K.

“…Step frequency decreased (−2.5 ± 3.6%) and step length increased (+2.6 ± 3.8%) over time (p < 0.05), independently of condition. …”
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