DmGluRA activity inhibits neuronal excitability via activation of the PI3K pathway. by Eric Howlett (268817)

“…A) Representative traces showing the decreased rate of onset of long-term facilitation (LTF) (I) and decreased excitatory junction potential (ejp) amplitude (II) in larvae overexpressing <i>PI3K-CAAX</i> in motor neurons compared to wildtype at the indicated [Ca²⁺], and the increased rate of onset of LTF and ejp amplitude in larvae overexpressing <i>PTEN</i>. …”

Characterization of hibiscus sabdariffa fiber as potential reinforcement for denture acrylic resins by Kenneth Nkemdilim Okeke (6071561)

“…The flexural strength was measured in line with ASTM D 790 using LloydTM three point bending machine. In line with ASTM D 256, the impact strength was measured using HounsfieldTM charpy tester. …”

Enrichment of Treg cells at the disease site of visceral leishmaniasis (VL) patients: by Ambak K. Rai (185132)

“…<p><b>A</b>) <b>Enumeration of FoxP3⁺ Treg cells:</b> On gated lymphocytes, expression of CD4 and CD25 was defined and subsequently expression of FoxP3 was observed among gated CD4⁺CD25⁺ cells. …”

DataSheet_1_Application of Diffusion Kurtosis Imaging in Evaluating Acute Xerostomia in Nasopharyngeal Carcinoma Treated With Induction Chemotherapy Plus Concurrent Chemoradiothera... by Da-Wei Zhao (1753762)

“…</p>Results<p>At each time point, sSFR was significantly higher than uSFR (p < 0.05 for all). …”

Arg36Ala mutation and protease inhibitors increase the cell surface expression of PAR2-GFP without a signal peptide. by Belinda Liu (8474187)

“…The experiments have been performed 3 times and very similar results have been observed. …”

DataSheet1_Pioglitazone treatment mitigates cardiovascular bioprosthetic degeneration in a chronic kidney disease model.PDF by Shintaro Katahira (19350541)

“…Animals were distributed into three groups for each time point: 1) control group receiving standard chow, 2) CKD group receiving 0.25% adenine and 3) CKD + pioglitazone group (300 mg per kg of 0.25% adenine chow). …”

Data_Sheet_1_Association between hemoglobin-to-red blood cell distribution width ratio and hospital mortality in patients with non-traumatic subarachnoid hemorrhage.PDF by Jiuling Liu (16327938)

“…The threshold inflection point value of 9.50 was calculated using RCS analysis. …”

Sensitivity analysis to determine the effect of varying inhibitor adhesion kinetics upon treatment efficacy. by Paul A. Roberts (5171447)

“…Treatment efficacy improves with increasing <i>α</i>_<i>A</i> and decreasing <i>β</i>_<i>A</i>. On average, treatment with a single inhibitor dose with continuous debridement is the most effective treatment, followed by regular inhibitor doses with regular debridement; a single inhibitor dose with regular debridement being the least effective of the three. …”

miR-204 suppressed HNSCC cell migration, adhesion and invasion <i>in vitro</i> and lung colonization <i>in vivo</i>. by Younghee Lee (6057)

“…Triplicate repeats were conducted at experimental point for <b>A</b> (Methods). For <b>B</b> and <b>C</b>, cells migrated to the basal side of the porous membrane was visualized with a Zeiss Axiovert microscope at ×20 magnification. 10 random fields from three replicate wells were counted and the number of cells that had migrated or invaded was presented as number of cells counted per field of the porous membrane (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000730#s4" target="_blank">Materials and Methods</a>). …”

Bifurcation Structure of Atypical and Conventional Models. by Christopher J. Knowlton (11450436)

“…Dynamics progress from a stable fixed point to a saddle node on an invariant limit cycle (SNIC) at -8 pA producing type 1 excitability. …”

Genetic Pathway in Acquisition and Loss of Vancomycin Resistance in a Methicillin Resistant <em>Staphylococcus aureus</em> (MRSA) Strain of Clonal Type USA300 by Susana Gardete (185488)

“…The availability of these 3 isogenic strains allowed us to explore genetic correlates of antibiotic resistance as it emerged <em>in vivo</em>. …”

Osteopontin Deletion Prevents the Development of Obesity and Hepatic Steatosis via Impaired Adipose Tissue Matrix Remodeling and Reduced Inflammation and Fibrosis in Adipose Tissue... by Andoni Lancha (335824)

“…Gene expression of collagens <i>Col1a1</i>, <i>Col6a1</i> and <i>Col6a3</i> in EWAT and liver, as well as the profibrotic cytokine <i>Tgfb1</i> in EWAT were increased with HFD, while OPN-deficiency prevented this increase. …”

Tradeoffs in network learning and memory. by Ann M. Hermundstad (215324)

“…<p>Best, worst, and average network performance is measured with respect to solutions and produced by the five networks shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002063#pcbi-1002063-g001" target="_blank">Figure 1(a)</a>. …”

Results from stepwise regression to establish the SAM² predictors that explained variance in the valence × neuroticism interaction in Studies 1-all, 2, and 3 (Fig 8). by Léo Dutriaux (3153684)

“…In the original analyses (left column), behavior regularity was regressed onto only valence and neuroticism in Model 2 from the analysis pipeline to test the valence × neuroticism interaction maximally. The five primary SAM² predictors (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0286954#pone.0286954.g001" target="_blank">Fig 1</a>) were then added one at a time into the original regression to assess how much each alone decreased the coefficient for the valence × neuroticism interaction (est_V×N). …”

Results from stepwise regression to establish the SAM² predictors that explained variance in the valence × self-control interaction in Studies 1-all, 2, and 3 (Fig 7). by Léo Dutriaux (3153684)

“…In the original analyses (left column), behavior regularity was regressed onto only valence and self-control in Model 2 from the analysis pipeline to test the valence × self-control interaction maximally. The five primary SAM² predictors (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0286954#pone.0286954.g001" target="_blank">Fig 1</a>) were then added one at a time into the original regression to assess how much each alone decreased the coefficient for the valence × self-control interaction (est_V×S). …”

Evolution of basal membrane properties over time in iPSC-derived neurons plated on POL. by Deborah Prè (5659969)

“…<p>A) The average resting membrane potential (RMP in mV) decreased over time. …”

Modulation of the persistent histamine responses by [Ca]_i and PKA. by Iustin V. Tabarean (302441)

“…Extracellular incubation with BAPTA-AM (1 mM) gradually decreases a persistent current activated by histamine (50 µM). …”

Mathematical model of hiPSC-CM APs. by Michael Xavier Doss (30403)

“…<b>D:</b> A larger block of I_Kr to 40% of the normal value elicits progressively decreasing oscillations of membrane potential leading eventually to the permanent depolarization at −12.8 mV.…”

Impact of the estimated glomerular filtration rate on long-term mortality in patients with hypertensive crisis visiting the emergency department by Jeong-Hun Shin (12207485)

Comparison of the effects of vaccination between stochastic and deterministic models for various values of <i>r</i>₀ and <i>I</i>₀. by Edwin C. Yuan (692914)

“…While the average epidemic size decreases monotonically with <i>V</i> (Figures A–C), the standard deviation of the large-scale epidemic size initially increases with increasing <i>V</i> (decreasing <i>r</i>_eff), reflecting greater variability as <i>r</i>_eff is reduced, similar to the increase in the width of the large-scale epidemic peak with decreasing <i>r</i>₀ in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0115826#pone.0115826.g001" target="_blank">Fig. 1A</a>. …”